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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-990</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-990</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Опыт применения фокусированного ультразвукового исследования сердца у пациентов с COVID-19 в Prone-позиции</article-title><trans-title-group xml:lang="en"><trans-title>The application experience of focused ultrasound heart examination in patients with COVID-19 in Prone-position</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2953-5570</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белавина</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Belavina</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белавина Наталья Ивановна – канд. мед. наук, врач отделения ультразвуковой и функциональной диагностики, сотрудник кардионефрологической лаборатории. SPIN-код 1712-7956</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Natalya I. Belavina – Cand. of Sci. (Med.), doctor of the Department of Ultrasound and Functional Diagnostics, staff-member of Laboratory of Cardionephrology. SPIN-код 1712-7956</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">natbelavina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2850-4465</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исхаков</surname><given-names>Р. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Iskhakov</surname><given-names>R. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исхаков Рустам Тимурович – заведующий отделением реанимации и интенсивной терапии больных нефрологического профиля</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Rustam T. Iskhakov – Head of the Resuscitation and Intensive Care Unit for Renal Patients</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">stamius@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0834-8426</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баркова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Barkova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баркова Юлия Владимировна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Iuliia V. Barkova – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">yulia.v.barkova@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6407-2095</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilina</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильина Елена Сергеевна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Elena S. Ilina – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">elena.ilina84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2877-9592</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кесарева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kesareva</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кесарева Юлия Александровна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Iuliia A. Kesareva – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">romakes@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0196-3744</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леоненко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leonenko</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Леоненко Наталья Владимировна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Natalya V. Leonenko – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">naleo69@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5477-5635</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Татьяна Андреевна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Tatyana A. Nikitina – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">dr.NikitinaTatyana@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7046-0318</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пирожкова</surname><given-names>Я. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pirozhkova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пирожкова Яна Владимировна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Iana V. Pirozhkova – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">pasha-pirzhkv@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4156-2299</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соколова Наталья Валерьевна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Natalia V. Sokolova – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">nataliesok@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9239-1982</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таймасханова</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Taymaskhanova</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таймасханова Патимат Алиасхабовна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Patimat A. Taymaskhanova – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">TAYMASKHANOVA.PATI@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1059-4941</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шищенко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishchenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шищенко Екатерина Алексеевна – врач отделения ультразвуковой и функциональной диагностики</p><p>123182 Москва, ул. Пехотная, д.3</p></bio><bio xml:lang="en"><p>Ekaterina A. Shishchenko – doctor of the Department of Ultrasound and Functional Diagnostics</p><p>3, Pekhotnaya str., Moscow 123182</p></bio><email xlink:type="simple">penelopaket@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0190-1620</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зелтынь-Абрамов</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zeltyn-Abramov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зелтынь-Абрамов Евгений Мартынович – доктор мед. наук, профессор, руководитель кардионефрологической лаборатории ГБУЗ ГКБ № 52; профессор кафедры терапии ФДПО ФГАОУ ВО РНИМУ имени Н.И. Пирогова</p><p>123182 Москва, ул. Пехотная, д.3117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Eugene M. Zeltyn-Abramov – Doct. of Sci. (Med.), Professor, Chief of Laboratory of Cardionephrology Moscow City Clinical Hospital No 52; Professor at the Department of Internal Medicine of the Faculty of Additional Professional Education</p><p>3, Pekhotnaya str., Moscow 123182house 1, Ostrivityanova str., Moscow 117997</p></bio><email xlink:type="simple">ezeltyn@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ города Москвы “Городская клиническая больница № 52 ДЗ города Москвы”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No52 of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ города Москвы “Городская клиническая больница № 52 ДЗ города Москвы”; ФГАОУ ВО “Российский национальный исследовательский медицинский университет имени Н.И. Пирогова” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No52 of Moscow Healthcare Department; Pirogov Russian National Research Medical University of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>13</day><month>09</month><year>2021</year></pub-date><volume>25</volume><issue>3</issue><fpage>13</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белавина Н.И., Исхаков Р.Т., Баркова Ю.В., Ильина Е.С., Кесарева Ю.А., Леоненко Н.В., Никитина Т.А., Пирожкова Я.В., Соколова Н.В., Таймасханова П.А., Шищенко Е.А., Зелтынь-Абрамов Е.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Белавина Н.И., Исхаков Р.Т., Баркова Ю.В., Ильина Е.С., Кесарева Ю.А., Леоненко Н.В., Никитина Т.А., Пирожкова Я.В., Соколова Н.В., Таймасханова П.А., Шищенко Е.А., Зелтынь-Абрамов Е.М.</copyright-holder><copyright-holder xml:lang="en">Belavina N.I., Iskhakov R.T., Barkova I.V., Ilina E.S., Kesareva I.A., Leonenko N.V., Nikitina T.A., Pirozhkova I.V., Sokolova N.V., Taymaskhanova P.A., Shishchenko E.A., Zeltyn-Abramov E.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/990">https://medvis.rdsmedia.ru/jour/article/view/990</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: изучение опыта применения фокусированного трансторакального эхокардиографического исследования в Prone-позиции (фЭхоPr) в отделениях реанимации и интенсивной терапии (ОРИТ) у пациентов с COVID-19.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В ретроспективное наблюдательное исследование включено 53 пациента (период 15.04–31.12.20). Критерии включения: подтвержденный диагноз COVID-19, наличие данных фЭхоPr, определенность исхода (выписка/смерть). Анализировались электронные истории болезни. фЭхоPr выполнялось в положении пациента на животе с валиком под левой частью грудной клетки и поднятой левой рукой (“поза пловца”). Проводилась оценка систолической функции правого желудочка (ПЖ) (измерение экскурсии фиброзного кольца трикуспидального клапана (TAPSE)), размера ПЖ, систолической функции левого желудочка (ЛЖ) (измерение интеграла линейной скорости кровотока в выходном тракте ЛЖ (VTIвтлж)), параметра ПЖ/ЛЖ, легочной гипертензии (ЛГ) (измерение пикового градиента трикуспидальной регургитации (PGTR)). В зависимости от результатов пациенты были разделены на 2 группы: информативные (+фЭхоPr) и неинформативные (−фЭхоPr) исследования.</p></sec><sec><title>Результаты</title><p>Результаты. Не выявлено статистически значимой разницы в группах (+фЭхоPr n = 35 vs -фЭхоPr n = 18) по возрасту (65,6 ± 15,3 года vs 60,2 ± 15,8 года, р &gt; 0,05), полу (муж.: 23 (65,7%) vs 14 (77,8%), р &gt; 0,05), индексу массы тела (31,3 ± 5,3 кг/м 2 vs 29,5 ± 5,4 кг/м2 , р &gt; 0,05), нахождению на искусственной вентиляции легких (ИВЛ) (24 (68,6%) vs 17 (94,4%), р = 0,074), показателям шкалы NEWS (6,9 ± 3,7 vs 8,5 ± 3,5 балла), летальности (82,8% vs 94,4%, р &gt; 0,05). Корреляционный анализ выявил умеренную обратную связь между нахождением на ИВЛ и информативностью исследования (r-Спирмена = −0,30 при р = 0,033). В группе +фЭхоPr корректное измерение TAPSE и ПЖ/ЛЖ проведено в 100%: снижение систолической функции ПЖ зафиксировано у 5 (14%), расширение ПЖ у 13 (37%) пациентов. Признаки ЛГ выявлены у 11 (31%), измерить PGTR не удалось у 10 (28%) человек. Систолическая дисфункция ЛЖ выявлена у 7 (20%). Не было выявлено патологии у 16 (46%) пациентов. У одного пациента диагностирован инфекционный эндокардит нативного митрального клапана, подтвердившийся при проведении аутопсии.</p></sec><sec><title>Заключение</title><p>Заключение. В 66% случаев проведение фЭхоPr было информативным, особенно в части оценки состояния правых отделов сердца. фЭхоPr – доступный, валидный и воспроизводимый метод оценки и мониторинга состояния сердца у пациентов в ОРИТ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim of the study</title><p>Aim of the study. To study the experience of using focused transthoracic echocardiography in patients with COVID-19 in prone position (fEchoPr) in intensive care units (ICU).</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The retrospective observational study included 53 patients (period from 15 April to 31 December 2020). Inclusion criteria: confirmed diagnosis of COVID-19, availability of fEchoPr data, outcome certainty (discharge/death). We analyzed electronic medical records. The fEchoPr was performed in patients in the prone position with a bolster under the left side of the chest and left arm raised (‘swimmer’s position’). We assessed the systolic function of the right ventricle (RV) (tricuspid annular plane systolic excursion (TAPSE)), RV size, RV/LV ratio, systolic function of the left ventricle (LV) (left ventricular outflow tract velocity time integral. (LVOT VTI)), and pulmonary hypertension (PH) (tricuspid regurgitation peak gradient (PGTR). Depending on the results, the patients were divided into 2 groups: informative (+fEchoPr) and non-informative (–fEchoPr) examinations.</p></sec><sec><title>Results</title><p>Results. There was no statistically significant difference in the groups (+fEcho n = 35 vs –fEcho n = 18) by age (65.6 ± 15.3 vs 60.2 ± 15.8, p &gt; 0.05), by gender (male: 23 (65.7%) vs 14 (77.8%), p &gt; 0.05), by body mass index (31.3 ± 5.3 kg/m 2 vs 29.5 ± 5.4 kg/m2 , p &gt; 0.05), by mechanical ventilation support (24 (68.6%) vs 17 (94.4%), p = 0.074), by NEWS scale indicators (6.9 ± 3.7 vs 8.5 ± 3.5 points), by mortality (82.8% vs 94.4%, p &gt; 0.05). Correlation analysis revealed a moderate inverse relationship between being on mechanical ventilation and the informative value of the study (Spearman's r = −0.30 at p = 0.033). In the +fEchoPr group, the correct measurement of TAPSE and RV/LV was carried out in 100%: a decrease in RV systolic function was recorded in 5 patients (14%), expansion of the RV in 13 patients (37%). Signs of PH were detected in 11 patients (31%), PGTR could not be measured in 10 patients (28%). LV systolic dysfunction was detected in 7 patients (20%). No pathology was detected in 16 patients (46%). One patient was diagnosed with infective endocarditis of native mitral valve, which was later confirmed by autopsy.</p></sec><sec><title>Conclusion</title><p>Conclusion. In 66% of cases, fEchoPr examinations were informative, especially in terms of assessing the state of the right heart. fEchoPr examination is an affordable, valid and reproducible method to assess and monitor the state of the heart in ICU patients.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>фокусированное эхокардиографическое исследование</kwd><kwd>Prone-позиция</kwd><kwd>искусственная вентиляция легких</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>focused echocardiographic examination</kwd><kwd>prone position</kwd><kwd>mechanical ventilation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Johns Hopkins University in medicine coronavirus resource Center. Available at: https://coronavirus.jhu.edu. Accessed on 03 February 2021.</mixed-citation><mixed-citation xml:lang="en">Johns Hopkins University in medicine coronavirus resource Center. Available at: https://coronavirus.jhu.edu. Accessed on 03 February 2021.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hussain A., Via G., Melniker L., Goffi A., Tavazzi G., Neri L., Villen T., Hoppmann R., Mojoli F., Noble V., Zieleskiewicz L., Blanco P., Ma I.W.Y., Wahab M.A., Alsaawi A., Al Salamah M., Balik M., Barca D., Bendjelid K, Bouhemad B., Bravo-Figueroa P., Breitkreutz R., Calderon J., Connolly J., Copetti R., Corradi F., Dean A.J., Denault A., Govil D., Graci C., Ha Y.R., Hurtado L., Kameda T., Lanspa M., Laursen C.B., Lee F., Liu R., Meineri M., Montorfano M., Nazerian P., Nelson B.P., Neskovic A.N., Nogue R., Osman A., Pazeli J., PereiraJunior E., Petrovic T., Pivetta E., Poelaert J., Price S., Prosen G., Rodriguez S., Rola P., Royse C., Chen Y.T., Wells M., Wong A., Xiaoting W., Zhen W., Arabi Y. Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus. Crit. Care. 2020; 24 (1): 702. https://doi.org/10.1186/s13054-020-03369-5</mixed-citation><mixed-citation xml:lang="en">Hussain A., Via G., Melniker L., Goffi A., Tavazzi G., Neri L., Villen T., Hoppmann R., Mojoli F., Noble V., Zieleskiewicz L., Blanco P., Ma I.W.Y., Wahab M.A., Alsaawi A., Al Salamah M., Balik M., Barca D., Bendjelid K, Bouhemad B., Bravo-Figueroa P., Breitkreutz R., Calderon J., Connolly J., Copetti R., Corradi F., Dean A.J., Denault A., Govil D., Graci C., Ha Y.R., Hurtado L., Kameda T., Lanspa M., Laursen C.B., Lee F., Liu R., Meineri M., Montorfano M., Nazerian P., Nelson B.P., Neskovic A.N., Nogue R., Osman A., Pazeli J., PereiraJunior E., Petrovic T., Pivetta E., Poelaert J., Price S., Prosen G., Rodriguez S., Rola P., Royse C., Chen Y.T., Wells M., Wong A., Xiaoting W., Zhen W., Arabi Y. Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus. Crit. Care. 2020; 24 (1): 702. https://doi.org/10.1186/s13054-020-03369-5</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Spencer K.T., Kimura B.J., Korcarz C.E., Pellikka P.A., Rahko P.S., Siegel R.J. Focused cardiac ultrasound: recommendations from the American Society of Echocardiography. J. Am. Soc. Echocardiogr. 2013; 26 (6): 567–581. http://doi.org/10.1016/j.echo.2013.04.001</mixed-citation><mixed-citation xml:lang="en">Spencer K.T., Kimura B.J., Korcarz C.E., Pellikka P.A., Rahko P.S., Siegel R.J. Focused cardiac ultrasound: recommendations from the American Society of Echocardiography. J. Am. Soc. Echocardiogr. 2013; 26 (6): 567–581. http://doi.org/10.1016/j.echo.2013.04.001</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kochi A.N., Tagliari A.P., Forleo G.B., Fassini G.M., Tondo C. Cardiac and arrhythmic complications in patients with COVID-19. J. Cardiovasc. Electrophysiol. 2020; 31 (5): 1003–1008. http://doi.org/10.1111/jce.14479</mixed-citation><mixed-citation xml:lang="en">Kochi A.N., Tagliari A.P., Forleo G.B., Fassini G.M., Tondo C. Cardiac and arrhythmic complications in patients with COVID-19. J. Cardiovasc. Electrophysiol. 2020; 31 (5): 1003–1008. http://doi.org/10.1111/jce.14479</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Venus K., Munshi L., Fralick M. Prone positioning for patients with hypoxic respiratory failure related to COVID-19. CMAJ. 2020; 192 (47): E1532–E1537. https://doi.org/10.1503/cmaj.201201</mixed-citation><mixed-citation xml:lang="en">Venus K., Munshi L., Fralick M. Prone positioning for patients with hypoxic respiratory failure related to COVID-19. CMAJ. 2020; 192 (47): E1532–E1537. https://doi.org/10.1503/cmaj.201201</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Navas-Blanco J.R., Dudaryk R. Management of Respiratory Distress Syndrome due to COVID-19 infection. BMC Anesthesiol. 2020; 20 (1): 177. http://doi.org/10.1186/s12871-020-01095-7</mixed-citation><mixed-citation xml:lang="en">Navas-Blanco J.R., Dudaryk R. Management of Respiratory Distress Syndrome due to COVID-19 infection. BMC Anesthesiol. 2020; 20 (1): 177. http://doi.org/10.1186/s12871-020-01095-7</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Royal College of Physicians. National Early Warning Score (NEWS): Standardising the assessment of acute illness severity in the NHS. Report of a working party. London: RCP, 2012. 47 p.</mixed-citation><mixed-citation xml:lang="en">Royal College of Physicians. National Early Warning Score (NEWS): Standardising the assessment of acute illness severity in the NHS. Report of a working party. London: RCP, 2012. 47 p.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of, Cardiovascular Imaging. Eur. Heart J. Cardiovasc. Imaging. 2016; 17 (4): 412. http://doi.org/10.1093/ehjci/jew041</mixed-citation><mixed-citation xml:lang="en">Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of, Cardiovascular Imaging. Eur. Heart J. Cardiovasc. Imaging. 2016; 17 (4): 412. http://doi.org/10.1093/ehjci/jew041</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hatle L., Angelsen B.A., Tromsdal A. Non-invasive estimation of pulmonary artery systolic pressure with Doppler ultrasound. Br. Heart J. 1981; 45(2): 157–165. http://doi.org/10.1136/hrt.45.2.157</mixed-citation><mixed-citation xml:lang="en">Hatle L., Angelsen B.A., Tromsdal A. Non-invasive estimation of pulmonary artery systolic pressure with Doppler ultrasound. Br. Heart J. 1981; 45(2): 157–165. http://doi.org/10.1136/hrt.45.2.157</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Skulstad H., Cosyns B., Popescu B.A. et al. COVID-19 pandemic and cardiac imaging: EACVI recommendations on precautions, indications, prioritization, and protection for patients and healthcare personnel. Eur. Heart J. Cardiovasc. Imaging. 2020; 21(6): 592–598. http://doi.org/10.1093/ehjci/jeaa072</mixed-citation><mixed-citation xml:lang="en">Skulstad H., Cosyns B., Popescu B.A. et al. COVID-19 pandemic and cardiac imaging: EACVI recommendations on precautions, indications, prioritization, and protection for patients and healthcare personnel. Eur. Heart J. Cardiovasc. Imaging. 2020; 21(6): 592–598. http://doi.org/10.1093/ehjci/jeaa072</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Шляхто Е.В., Конради А.О., Арутюнов Г.П., Арутюнов А.Г., Баутин А.Е., Бойцов С.А., Виллевальде С.В., Григорьева Н.Ю., Дупляков Д.В., Звартау Н.Э., Козиолова Н.А., Лебедев Д.С., Мальчикова С.В., Медведева Е.А., Михайлов Е.Н., Моисеева О.М., Орлова Я.А., Павлова Т.В., Певзнер Д.В., Петрова М.М., Ребров А.П., Ситникова М.Ю., Соловьева А.Е., Тарловская Е.И., Трукшина М.А., Федотов П.А., Фомин И.В., Хрипун А.В., Чесникова А.И., Шапошник И.И., Явелов И.С., Яковлев А.Н. Руководство по диагностике и лечению болезней системы кровообращения в контексте пандемии COVID-19. Российский кардиологический журнал. 2020; 25 (3): 3801. https://doi.org/10.15829/1560-4071-2020-3-3801</mixed-citation><mixed-citation xml:lang="en">Shlyakho E.V., Konradi A.O., Arutyunov G.P., Arutyunov A.G., Bautin A.E., Boytsov S.A., Villevalde S.V., Grigoryeva N.Yu., Duplyakov D.V., Zvartau N.E., Koziolova N.A., Lebedev D.S., Malchikova S.V., Medvedeva E.A., Mikhailov E.N., Moiseeva O.M., Orlova Y.A., Pavlova T.V., Pevsner D.V., Petrova M.M., Rebrov A.P., Sitnikova M.Yu., Solovyova A.E., Tarlovskaya E.I., Trukshina M.A., Fedotov P.A., Fomin I.V., Khripun A.V., Chesnikova A.I., Shaposhnik I.I., Yavelov I.S., Yakovlev A.N. Guidelines for the diagnosis and treatment of circulatory diseases in the context of the COVID-19 pandemic. Russian Journal of Cardiology. 2020; 25 (3): 3801. https://doi.org/10.15829/1560-4071-2020-3-3801 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Dweck M.R., Bularga A., Hahn R.T., Bing R., Lee K.K., Chapman A.R., White A., Salvo G.D., Sade L.E., Pearce K., Newby D.E., Popescu B.A., Donal E., Cosyns B., Edvardsen T., Mills N.L., Haugaa K. Global evaluation of echocardiography in patients with COVID-19. Eur. Heart. J. Cardiovasc. Imaging. 2020; 21 (9): 949–958. http://doi.org/10.1093/ehjci/jeaa178</mixed-citation><mixed-citation xml:lang="en">Dweck M.R., Bularga A., Hahn R.T., Bing R., Lee K.K., Chapman A.R., White A., Salvo G.D., Sade L.E., Pearce K., Newby D.E., Popescu B.A., Donal E., Cosyns B., Edvardsen T., Mills N.L., Haugaa K. Global evaluation of echocardiography in patients with COVID-19. Eur. Heart. J. Cardiovasc. Imaging. 2020; 21 (9): 949–958. http://doi.org/10.1093/ehjci/jeaa178</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Giustino G., Croft L.B., Stefanini G.G., Bragato R., Silbiger J.J., Vicenzi M., Danilov T., Kukar N., Shaban N., Kini A., Camaj A., Bienstock S.W., Rashed E.R., Rahman K., Oates C.P., Buckley S., Elbaum L.S., Arkonac D., Fiter R., Singh R., Li E., Razuk V., Robinson S.E., Miller M., Bier B., Donghi V., Pisaniello M., Mantovani R., Pinto G., Rota I., Baggio S., Chiarito M., Fazzari F., Cusmano I., Curzi M., Ro R., Malick W., Kamran M., Kohli-Seth R., Bassily-Marcus A.M., Neibart E., Serrao G., Perk G., Mancini D., Reddy V.Y., Pinney S.P., Dangas G., Blasi F., Sharma S.K., Mehran R., Condorelli G., Stone G.W., Fuster V., Lerakis S., Goldman M.E. Characterization of Myocardial Injury in Patients With COVID-19. J. Am. Coll. Cardiol. 2020; 76(18): 2043–2055. http://doi.org/10.1016/j.jacc.2020.08.069</mixed-citation><mixed-citation xml:lang="en">Giustino G., Croft L.B., Stefanini G.G., Bragato R., Silbiger J.J., Vicenzi M., Danilov T., Kukar N., Shaban N., Kini A., Camaj A., Bienstock S.W., Rashed E.R., Rahman K., Oates C.P., Buckley S., Elbaum L.S., Arkonac D., Fiter R., Singh R., Li E., Razuk V., Robinson S.E., Miller M., Bier B., Donghi V., Pisaniello M., Mantovani R., Pinto G., Rota I., Baggio S., Chiarito M., Fazzari F., Cusmano I., Curzi M., Ro R., Malick W., Kamran M., Kohli-Seth R., Bassily-Marcus A.M., Neibart E., Serrao G., Perk G., Mancini D., Reddy V.Y., Pinney S.P., Dangas G., Blasi F., Sharma S.K., Mehran R., Condorelli G., Stone G.W., Fuster V., Lerakis S., Goldman M.E. Characterization of Myocardial Injury in Patients With COVID-19. J. Am. Coll. Cardiol. 2020; 76(18): 2043–2055. http://doi.org/10.1016/j.jacc.2020.08.069</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Piehl M.A., Brown R.S. Use of extreme position changes in acute respiratory failure. Crit. Care Med. 1976; 4 (1): 13–14. http://doi.org/10.1097/00003246-197601000-00003</mixed-citation><mixed-citation xml:lang="en">Piehl M.A., Brown R.S. Use of extreme position changes in acute respiratory failure. Crit. Care Med. 1976; 4 (1): 13–14. http://doi.org/10.1097/00003246-197601000-00003</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Bellani G., Laffey J.G., Pham T., Fan E., Brochard L., Esteban A., Gattinoni L., van Haren F., Larsson A., McAuley D.F., Ranieri M., Rubenfeld G., Thompson B.T., Wrigge H., Slutsky A.S., Pesenti A; LUNG SAFE Investigators; ESICM Trials Group. Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA. 2016; 23; 315 (8): 788–800. http://doi.org/10.1001/jama.2016.0291</mixed-citation><mixed-citation xml:lang="en">Bellani G., Laffey J.G., Pham T., Fan E., Brochard L., Esteban A., Gattinoni L., van Haren F., Larsson A., McAuley D.F., Ranieri M., Rubenfeld G., Thompson B.T., Wrigge H., Slutsky A.S., Pesenti A; LUNG SAFE Investigators; ESICM Trials Group. Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA. 2016; 23; 315 (8): 788–800. http://doi.org/10.1001/jama.2016.0291</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Munshi L., Del Sorbo L., Adhikari N.K.J., Hodgson C.L., Wunsch H., Meade M.O., Uleryk E., Mancebo J., Pesenti A., Ranieri V.M., Fan E. Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and MetaAnalysis. Ann. Am. Thorac. Soc. 2017; 14 (Suppl. 4): S280S288. http://doi.org/10.1513/AnnalsATS.201704-343OT</mixed-citation><mixed-citation xml:lang="en">Munshi L., Del Sorbo L., Adhikari N.K.J., Hodgson C.L., Wunsch H., Meade M.O., Uleryk E., Mancebo J., Pesenti A., Ranieri V.M., Fan E. Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and MetaAnalysis. Ann. Am. Thorac. Soc. 2017; 14 (Suppl. 4): S280S288. http://doi.org/10.1513/AnnalsATS.201704-343OT</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Giustiniano E., Fazzari F., Bragato R.M., Curzi M., Cecconi M. Trans-thoracic Echocardiography in Prone Positioning COVID-19 Patients: a Small Case Series. SN Compr. Clin. Med. 2020; 15: 1–6. http://doi.org/10.1007/s42399-020-00516-5</mixed-citation><mixed-citation xml:lang="en">Giustiniano E., Fazzari F., Bragato R.M., Curzi M., Cecconi M. Trans-thoracic Echocardiography in Prone Positioning COVID-19 Patients: a Small Case Series. SN Compr. Clin. Med. 2020; 15: 1–6. http://doi.org/10.1007/s42399-020-00516-5</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson L.E., Di Fenza R., Berra L., Bittner E.A., Chang M.G. Transthoracic Echocardiography in Prone Patients With Acute Respiratory Distress Syndrome: A Feasibility Study. Crit. Care. Explor. 2020; 2(8): e0179. http://doi.org/10.1097/CCE.0000000000000179</mixed-citation><mixed-citation xml:lang="en">Gibson L.E., Di Fenza R., Berra L., Bittner E.A., Chang M.G. Transthoracic Echocardiography in Prone Patients With Acute Respiratory Distress Syndrome: A Feasibility Study. Crit. Care. Explor. 2020; 2(8): e0179. http://doi.org/10.1097/CCE.0000000000000179</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Grasselli G., Zangrillo A., Zanella A., et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020; 323 (16): 1574–1581. http://doi.org/10.1001/jama.2020.5394</mixed-citation><mixed-citation xml:lang="en">Grasselli G., Zangrillo A., Zanella A., et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020; 323 (16): 1574–1581. http://doi.org/10.1001/jama.2020.5394</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Jaglan A., Kaminski A., Payne A., Salinas P.D., Khandheria B.K. Focus, not point-of-care, echocardiography in prone position: It can be done in COVID-19 patients. CASE (Phila). 2020; 26. http://doi.org/10.1016/j.case.2020.10.007</mixed-citation><mixed-citation xml:lang="en">Jaglan A., Kaminski A., Payne A., Salinas P.D., Khandheria B.K. Focus, not point-of-care, echocardiography in prone position: It can be done in COVID-19 patients. CASE (Phila). 2020; 26. http://doi.org/10.1016/j.case.2020.10.007</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">García-Cruz E., Manzur-Sandoval D., Gopar-Nieto R., Murillo-Ochoa A.L., Bejarano-Alva G., Rojas-Velasco G., Álvarez-Álvarez R.J., Baranda-Tovar F. Transthoracic echocardiography during prone position ventilation: Lessons from the COVID-19 pandemic. J. Am. Coll. Emerg. Physicians. Open. 2020; 2 (5): 730–736. http:// doi.org/10.1002/emp2.12239</mixed-citation><mixed-citation xml:lang="en">García-Cruz E., Manzur-Sandoval D., Gopar-Nieto R., Murillo-Ochoa A.L., Bejarano-Alva G., Rojas-Velasco G., Álvarez-Álvarez R.J., Baranda-Tovar F. Transthoracic echocardiography during prone position ventilation: Lessons from the COVID-19 pandemic. J. Am. Coll. Emerg. Physicians. Open. 2020; 2 (5): 730–736. http:// doi.org/10.1002/emp2.12239</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Santos-Martínez L.E., Mendoza-Copa G., García-Cruz E., Álvarez-Álvarez R.J,. Bucio-Reta R.E., González-Ruiz F.J., Ramos-Enríquez Á., Hernández-Márquez M.Á., BarandaTovar F.M. Feasibility in the echocardiographic estimation of parameters of the right ventricle in prone position. Arch. Cardiol. Mex. 2020; 90 (2): 130–137. English. http://doi.org/10.24875/ACM.19000195</mixed-citation><mixed-citation xml:lang="en">Santos-Martínez L.E., Mendoza-Copa G., García-Cruz E., Álvarez-Álvarez R.J,. Bucio-Reta R.E., González-Ruiz F.J., Ramos-Enríquez Á., Hernández-Márquez M.Á., BarandaTovar F.M. Feasibility in the echocardiographic estimation of parameters of the right ventricle in prone position. Arch. Cardiol. Mex. 2020; 90 (2): 130–137. English. http://doi.org/10.24875/ACM.19000195</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Szekely Y., Lichter Y., Taieb P., Banai A., Hochstadt A., Merdler I., Gal Oz A., Rothschild E., Baruch G., Peri Y., Arbel Y., Topilsky Y. Spectrum of Cardiac Manifestations in COVID-19: A Systematic Echocardiographic Study. Circulation. 2020; 142 (4): 342–353. http://doi.org/10.1161/CIRCULATIONAHA.120.047971</mixed-citation><mixed-citation xml:lang="en">Szekely Y., Lichter Y., Taieb P., Banai A., Hochstadt A., Merdler I., Gal Oz A., Rothschild E., Baruch G., Peri Y., Arbel Y., Topilsky Y. Spectrum of Cardiac Manifestations in COVID-19: A Systematic Echocardiographic Study. Circulation. 2020; 142 (4): 342–353. http://doi.org/10.1161/CIRCULATIONAHA.120.047971</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
