medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.10.24835/1607-0763-2020-2-119-130medvis-918Research ArticleГОЛОВАHEADОпределение эффективности использования счета в качестве фМРТ-парадигмы при исследовании функциональных связей в норме для оценки управляющих функций мозгаEvaluation of fMRI counting task efficiency for normal brain functional connectivity analisys during executive function examinationhttps://orcid.org/0000-0002-9093-344XМорозоваС. Н.MorozovaS, N.

Морозова Софья Николаевна – канд. мед. наук, научный сотрудник отделения лучевой диагностики

125367 Москва, Волоколамское шоссе, д. 80

Sofya N. Morozova – Cand. of Sci. (Med.), research fellow in radiology department

80, Volokolamskoye Shosse, 125367, Moscow

https://orcid.org/0000-0001-9396-6063КремневаЕ. И.KremnevaE. I.

Кремнева Елена Игоревна – канд. мед. наук, старший научный сотрудник отделения лучевой диагностики

125367 Москва, Волоколамское шоссе, д. 80

Elena I. Kremneva – Cand. of Sci. (Med.), major research fellow in radiology department

80, Volokolamskoye Shosse, 125367, Moscow

https://orcid.org/0000-0001-7498-4063ГаджиеваЗ. Ш.GadzhievaZ. Sh.

Гаджиева Зухра Шарапутдиновна – канд. мед. наук, врач-невролог 3-го неврологического отделения

125367 Москва, Волоколамское шоссе, д. 80

Zukhra Sh. Gadzhieva – Cand. of Sci. (Med.), neurologist of 3rd neurological department

80, Volokolamskoye Shosse, 125367, Moscow

https://orcid.org/0000-0003-4461-3338АхметзяновБ. М.AkhmetzyanovB. M.

Ахметзянов Булат Митхатович – канд. мед. наук, врач-рентгенолог, обособленное подразделение Филиал

450054 Уфа, ул. Рихарда Зорге, д. 58, стр. 2

Bulat M. Akhmetzyanov – Cand. of Sci. (Med.), radiologist

58-2, Richard Sorge str., 450054, Ufa

https://orcid.org/0000-0003-3820-4554КротенковаМ. В.KrotenkovaM. V.

Кротенкова Марина Викторовна – доктор мед. наук, заведующая отделением лучевой диагностики

125367 Москва, Волоколамское шоссе, д. 80

Marina V. Krotenkova – Doct. of Sci. (Med.), head of the radiology department

80, Volokolamskoye Shosse, 125367, Moscow

https://orcid.org/0000-0001-9929-2725ДобрынинаЛ. А.DobryninaL. A.

Добрынина Лариса Анатольевна – доктор мед. наук, заведующая 3 неврологическим отделением

125367 Москва, Волоколамское шоссе, д. 80

Larisa A. Dobrynina – Doct. of Sci. (Med.), head of the 3rd neurological department

80, Volokolamskoye Shosse, 125367, Moscow

ФГБНУ “Научный центр неврологии”РоссияFederal State Budgetary Scientific Institution “Research Center of Neurology”Russian FederationООО “ПЭТ-Технолоджи”РоссияPET-TechnologyRussian Federation202018062020242Медицинская визуализация 2020№2119130Copyright © Морозова С.Н., Кремнева Е.И., Гаджиева З.Ш., Ахметзянов Б.М., Кротенкова М.В., Добрынина Л.А., 20202020Морозова С.Н., Кремнева Е.И., Гаджиева З.Ш., Ахметзянов Б.М., Кротенкова М.В., Добрынина Л.А.Morozova S.N., Kremneva E.I., Gadzhieva Z.S., Akhmetzyanov B.M., Krotenkova M.V., Dobrynina L.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.rdsmedia.ru/jour/article/view/918Цель исследования

Цель исследования: сравнительный анализ функциональных связей коры головного мозга при выполнении модификаций теста Струпа и теста счет про себя.

Материал и методы

Материал и методы. Исследование было проведено на 18 здоровых добровольцах, которым выполнялась фМРТ на 3 Тл магнитно-резонансном томографе с использованием двух блоковых парадигм: модификаций теста Струпа и теста счет про себя.

Результаты

Результаты. Анализ функциональных связей при обработке данных фМРТ показал, что, несмотря на вовлечение сходных структур, характер распределения связей отличается: при выполнении теста Струпа межполушарные связи наблюдались между передними отделами островка, а при счете про себя – латеральной префронтальной корой с обеих сторон и нижними отделами теменных долей с обеих сторон. Различия распределения связей обусловлены, вероятно, спецификой предложенных заданий. При сравнительном анализе корреляций парадигмы значимо отличались по связям со зрительной корой, которые были больше при выполнении модификации теста Струпа.

Заключение

Заключение. Полученные данные свидетельствуют о возможности эффективного альтернативного использования модификации теста счет про себя для оценки управляющих функций мозга, а также его преимуществах при обследовании пациентов с нарушениями зрения.

Aim

Aim: to explore functional connectivity of the normal brain during Stroop test modification and new suggested counting test performance.

Materials and methods

Materials and methods. Data were acquired from 18 healthy volunteers who underwent fMRI examination on 3T scanner with Stroop test modification and new suggested counting test used as block paradigms.

Results

Results. Functional connectivity analysis showed involvement of similar regions but with different distribution of positive correlations between them: interhemispheric significant positive correlations during Stroop test modification performance were found between anterior insular cortex, interhemispheric significant positive correlations during counting test performance were found between dorsolateral prefrontal cortices bilaterally and inferior parietal cortices bilaterally. Different distribution of significant correlations could be due to specificity of tasks. Comparative analysis showed significantly higher positive correlations with occipital cortex during Stroop test performance.

Conclusions

Conclusions. Received data allow alternative use of the abovementioned paradigms for executive functions investigation, with preference for counting test paradigm in patients with vision disturbances.

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The authors declare that there are no conflicts of interest present.