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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-2020-1-119-132</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-895</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВЫЕ ТЕХНОЛОГИИ ЛУЧЕВЫХ ИССЛЕДОВАНИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEW TECHNOLOGIES IN RADIOLOGY</subject></subj-group></article-categories><title-group><article-title>Биохимические основы визуализации при позитронной эмиссионной томографии в онкологии. Часть 2</article-title><trans-title-group xml:lang="en"><trans-title>Biochemical basics of imaging in positron emission tomography in oncology. Part 2</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6345-9500</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леонтьев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leontyev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, заведующий отделением радионуклидной диагностики 125284 Москва, 2 -й Боткинский пр., д. 3, Российская Федерация</p><p>Тел.: +7 (495) 9458718</p></bio><bio xml:lang="en"><p>Phone: +7 (495) 945-87-18 </p><p> </p><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">aleksleont@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8378-4338</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рубцова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rubtsova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">rna17@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8905-4202</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халимон</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khalimon</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">markyhaws@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4864-0643</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамадеева</surname><given-names>Г. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamadeeva</surname><given-names>G. F.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">g.hamadeeva@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3508-1782</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулиев</surname><given-names>М. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuliev</surname><given-names>M. T.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Resident of Oncology, Radiotherapy and Plastic Surgery Department of Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) based at the Nuclear Medicine Department </p><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">kul502@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1280-620X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пылова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pylova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">irinapylova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7835-4939</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазутина</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazutina</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">t.n.lazutina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0792-6012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Doct. of Sci. (Med.), Professor, First Deputy of General director of “National Medical Research Center of Radiology” of the Ministry of Healthcare of Russia, Head of Urological, oncological and radiological department of Faculty of advanced training of medical workers of medical institute of The Peoples' Friendship University of Russia</p><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">andocrey@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8784-8415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Full Member of the Russian Academy of Sciences, Corresponding member of Russian Academy of Education, Doct. of Sci. (Med.), Professor, Honored Doctor of the Russian Federation, Chief urologist of the Russian Academy of Sciences, General Director of “National Medical Radiological Research Center” of the Ministry of Healthcare of Russia, Head of Department of urology and surgical  nephrology with a course of oncourology at the medical faculty of medical institute of The Peoples' Friendship University of Russia</p><p>3, 2nd Botkinsky pr., Moscow 125284, Russian Federation</p></bio><email xlink:type="simple">kaprin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МНИОИ имени П.А. Герцена – филиал ФГБУ “Национальный медицинский исследовательский центр радиологии” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>P.A. Herzen Moscow Research Oncology Institute – branch of “National Medical Research Center of Radiology” of the Ministry of Healthcare of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>02</day><month>05</month><year>2020</year></pub-date><volume>24</volume><issue>1</issue><issue-title>Медицинская визуализация 2020№1</issue-title><fpage>119</fpage><lpage>132</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Леонтьев А.В., Рубцова Н.А., Халимон А.И., Хамадеева Г.Ф., Кулиев М.Т., Пылова И.В., Лазутина Т.Н., Костин А.А., Каприн А.Д., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Леонтьев А.В., Рубцова Н.А., Халимон А.И., Хамадеева Г.Ф., Кулиев М.Т., Пылова И.В., Лазутина Т.Н., Костин А.А., Каприн А.Д.</copyright-holder><copyright-holder xml:lang="en">Leontyev A.V., Rubtsova N.A., Khalimon A.I., Khamadeeva G.F., Kuliev M.T., Pylova I.V., Lazutina T.N., Kostin A.A., Kaprin A.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/895">https://medvis.rdsmedia.ru/jour/article/view/895</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>ПЭТ/КТ</kwd><kwd>радиофармпрепараты</kwd><kwd>РФП</kwd><kwd>рецепторная визуализация</kwd><kwd>лиганды к рецепторам</kwd><kwd>RGD-пептиды</kwd><kwd>нейроэндокринные опухоли</kwd><kwd>DOTA-пептиды</kwd><kwd>DOTATATE</kwd><kwd>DOTATOC</kwd><kwd>DOTANOC</kwd><kwd>лиганды к ПСМА</kwd><kwd>лиганды к эстрогеновым рецепторам</kwd><kwd>ФЭС</kwd><kwd>лиганды к рецепторам половых гормонов</kwd><kwd>EGFR</kwd></kwd-group><kwd-group xml:lang="en"><kwd>PET/CT</kwd><kwd>radiopharmaceuticals</kwd><kwd>receptor imaging</kwd><kwd>receptor ligands</kwd><kwd>RGD-peptides</kwd><kwd>NET</kwd><kwd>DOTA-conjugated&#13;
peptides</kwd><kwd>DOTATATE</kwd><kwd>DOTATOC</kwd><kwd>DOTANOC</kwd><kwd>PSMA ligands</kwd><kwd>estrogen receptors imaging</kwd><kwd>FES</kwd><kwd>sex hormone imaging</kwd><kwd>EGFR</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Brooks P.C., Strömblad S., Sanders L.C., von Schalscha T.L., Aimes R.T., Stetler-Stevenson W.G., Quigley J.P., Cheresh D.A. Localization of matrix metalloproteinase</mixed-citation><mixed-citation xml:lang="en">Brooks P.C., Strömblad S., Sanders L.C., von Schalscha T.L., Aimes R.T., Stetler-Stevenson W.G., Quigley J.P., Cheresh D.A. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. 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