medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.10.24835/1607-0763-2019-4-76-85medvis-840Research ArticleЖИВОТABDOMENМалигнизация гепатоцеллюлярной аденомыMalignant transformation of a hepatocellular adenomahttps://orcid.org/0000-0003-1779-003XМедведеваБ. М.MedvedevaB. M.

доктор мед. наук, ведущий научный сотрудник рентгенодиагностического отделения НИИ клинической и экспериментальной радиологии

Dr. of Sci. (Med.), lead researcher, Diagnostic Radiology department of the Research Institute of Clinical and Experimental radiology

ХайцманД. М.KhaitsmanD. M.

ординатор лаборатории интервенционной радиологии НИИ клинической и экспериментальной радиологии

115478, Москва, Каширское шоссе, д. 23

Тел.: +7-916-251-55-52

resident of the interventional radiology laboratory of the Research Institute of Clinical and Experimental radiology

115478, Moscow, Kashirskoe shosse, 24

Phone: +7-916-251-55-52

d.khaitsman@gmail.comhttps://orcid.org/0000-0002-7021-6419ЛукьянченкоА. Б.LukianchenkoA. B.

доктор мед. наук, профессор, ведущий научный сотрудник рентгенодиагностического отделения НИИ клинической и экспериментальной радиологии

Dr. of Sci. (Med.), Professor, lead researcher, Diagnostic Radiology department of the Research Institute of Clinical and Experimental radiology

https://orcid.org/0000-0003-3565-4058МорозЕ. А.MorozE. A.

канд. мед. наук, старший научный сотрудник патологоанатомического отделения отдела морфологической и молекулярно-генетической диагностики опухолей НИИ клинической онкологии имени Н.Н. Трапезникова

Cand. of Sci. (Med.), senior researcher, Pathology department of N.N.Trapeznikov Research Institute of Clinical oncology

ФГБУ “ Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина” Минздрава РоссииРоссияN.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of RussiaRussian Federation201925122019047685Copyright © Медведева Б.М., Хайцман Д.М., Лукьянченко А.Б., Мороз Е.А., 20192019Медведева Б.М., Хайцман Д.М., Лукьянченко А.Б., Мороз Е.А.Medvedeva B.M., Khaitsman D.M., Lukianchenko A.B., Moroz E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.rdsmedia.ru/jour/article/view/840

Гепатоцеллюлярная аденома (ГЦА) – редкая доброкачественная опухоль печени, связанная с моноклональной пролиферацией зрелых гепатоцитов. ГЦА обладают большим спектром генетических и молекулярных характеристик, которые обусловливают их биологическое поведение (в частности, потенциал озлокачествления), однако особенности МР картины выделены только для двух подтипов (H-HCA и I-ICA). В данной статье представлено клиническое наблюдение малигнизации ГЦА на фоне динамического наблюдения аденоматоза у женщины 58 лет с гепатитом С.

Hepatocellular adenoma (HCA) is the uncommon benign liver tumor, which is characterized by monoclonal proliferation of mature hepatocytes. HCAs have many genetic and molecular features that determine their natural behavior (such as malignant transformation), but MRI features are studied just for two subtypes (H-HCA и I-ICA). This article presents clinical case of 58 y.o. woman with hepatitis C, hepatic adenomatosis and malignant transformation of one of multiple HCAs.

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The authors declare that there are no conflicts of interest present.