medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.10.24835/1607-0763-2018-5-21-30medvis-651Research ArticleМОЛОЧНАЯ ЖЕЛЕЗАBREASTРоль и возможности автоматизированного ультразвукового сканирования в скрининге рака молочной железы у женщин с высокой плотностью тканей молочных железThe role and possibilities of automated breast ultrasound in breast cancer screening in women with high density breast tissueСолодкийВ. А.SolodkyV. A.

академик РАН, доктор мед. наук, профессор, директор

academician of the Russian Academy of Sciences, doct. of med. sci., Professor, Director

МескихЕ. В.MeskichE. V.

доктор мед. наук, профессор, заведующая лабораторией рентгенорадиологических, ультразвуковых и рентгенохирургических технологий в маммологии (Федеральный маммологический центр) научно-исследовательского отдела раннего канцерогенеза, профилактики, диагностики и комплексного лечения онкологических заболеваний женских репродуктивных органов

doct. of med. sci., Professor, head laboratory of x-ray radiological, ultrasonic and x-ray surgical technologies in mammology (Federal mammological center) of the research Department of early  carcinogenesis, prevention, diagnosis and complex treatment of cancer of female reproductive organs

ЭрштейнМ. А.ErsteinM. A.

младший научный сотрудник лаборатории рентгенорадиологических, ультразвуковых и рентгенохирургических технологий в маммологии (Федеральный маммологический центр) научно-исследовательского отдела раннего канцерогенеза, профилактики, диагностики и комплексного лечения онкологических заболеваний  женских репродуктивных органов

117997 Москва, ул. Профсоюзная, д. 86

Junior researcher of the laboratory of radiological, ultrasound and x-ray surgical technologies in mammology (Federal mammological center) of the research Department of early carcinogenesis, prevention, diagnosis and treatment of cancer of female reproductive organs

117997 Moscow, Russia, Profsojuznaja str., 86

margarita.ershtein@gmail.comКолесникА. Ю.KolesnikA. Yu.

канд. мед. наук, научный сотрудник лаборатории рентгенорадиологических, ультразвуковых и рентгенохирургических технологий в маммологии (Федеральный маммологический центр) научно-исследовательского отдела раннего канцерогенеза, профилактики, диагностики и комплексного лечения онкологических заболеваний женских репродуктивных органов

cand. of med. sci., researcher at the laboratory of radiological, ultrasound and x-ray surgical technologies in mammology (Federal mammological center) of the research Department of early carcinogenesis, prevention, diagnosis and treatment of cancer of female reproductive organs

ОксанчукЕ. А.OksanchukE. A.

канд. мед. наук, научный сотрудник лаборатории рентгенорадиологических, ультразвуковых и рентгенохирургических технологий в маммологии (Федеральный маммологический центр) научно-исследовательского отдела раннего канцерогенеза, профилактики, диагностики и комплексного лечения онкологических заболеваний женских репродуктивных органов

cand. of med. sci., researcher of the laboratory of radiology and nuclear medicine, ultrasound and x-ray technologies 3 mammalogy (Federal breast center) research Department of early carcinogenesis, prevention, diagnosis and complex treatment of oncological diseases of female reproductive organs

НудновН. В.NudnovN. V.

доктор мед. наук, профессор, заместитель директора по научной работе

doct. of med. sci., professor

ФГБУ “Российский научный центр рентгенорадиологии”Россия“Russian scientific center of radiology”Russian Federation201828102018052130Copyright © Солодкий В.А., Меских Е.В., Эрштейн М.А., Колесник А.Ю., Оксанчук Е.А., Нуднов Н.В., 20182018Солодкий В.А., Меских Е.В., Эрштейн М.А., Колесник А.Ю., Оксанчук Е.А., Нуднов Н.В.Solodky V.A., Meskich E.V., Erstein M.A., Kolesnik A.Y., Oksanchuk E.A., Nudnov N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.rdsmedia.ru/jour/article/view/651

Целью исследования стало повышение эффективности диагностики образований молочных желез на плотном фоне. В исследовании участвовало 399 женщин с плотным рентгенологическим фоном (ACRC, DBIRADS 2015) в возрасте от 20 до 83 лет (средний возраст 43,65 года). Женщинам были проведены стандартная цифровая рентгеновская маммография (МГ) в двух проекциях, ручное ультразвуковое исследование (УЗИ) и автоматизированное ультразвуковое сканирование (АУС) молочных желез в трех проекциях. Оценка производилась в группах МГ, МГ+АУС, МГ+УЗИ. Установлено, что добавление АУС к МГ в базовом алгоритме исследования повышает эффективность диагностики узловых образований: повышение чувствительности на 22,9% (МГ – 75,9%, МГ+АУС – 98,8%), снижение специфичности на 6,95% (МГ – 86,7%, МГ+АУС – 79,75%), добавленная ценность составляет 10,6%. Добавленная ценность АУС и УЗИ равны, однако АУС позволяет стандартизировать, хранить и передавать полученные данные с возможностью второго чтения, а также позволяет сократить время интерпретации исследования в 2 раза по сравнению с УЗИ. Таким образом, АУС молочных желез может быть использовано в качестве дополнительного метода скрининга для женщин с плотным рентгенологическим фоном или как основной метод массового обследования для женщин молодого возраста.

The aim of our study was to improve the diagnosis of breast nodules on a high dense breast tissue. The study involved 280 women with high dense breast tissue (ACR C,D BI-RADS 2015) aged 26 to 83 years (mean age 47.5 years), all women underwent standard digital mammography in two projections and automated breast ultrasound scanning in three projections. The addition of ABUS to mammography in the basic algorithm of the study increases the effectiveness of the diagnosis of nodules: increased sensitivity by 22.9% (MG – 75.9%, MG+ABUS – 98.8%), reduced specificity by 6.95% (MG – 86.7%, MG+ABUS – 79.75%), the added value is 11.25%. The added value of ABUS and HHUS are equal, but the ABUS allows to standardize, store and transmit the data with the possibility of a second reading, as well as to reduce the time of interpretation of the study twice in comparison with HHUS. Thus, ABUS can be used as an additional screening method for women with high dense breast or as the main method of mass examination for young women.

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The authors declare that there are no conflicts of interest present.