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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvis-57</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МАЛЫЙ ТАЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SMALL PELVIS</subject></subj-group></article-categories><title-group><article-title>МРТ-стадирование рака тела матки: проблема дифференциации яичниковых образований</article-title><trans-title-group xml:lang="en"><trans-title>MR-Staging of Cancer of the Corpus Uteri: Problem of Ovarian Lesions Differentiation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прошина</surname><given-names>Юлия Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Proshina</surname><given-names>Yuliya Viktorovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прошин</surname><given-names>Алексей Анатольевич</given-names></name><name name-style="western" xml:lang="en"><surname>Proshin</surname><given-names>Aleksei Anatolevich</given-names></name></name-alternatives><email xlink:type="simple">Al.Proshin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Березовская</surname><given-names>Татьяна Павловна</given-names></name><name name-style="western" xml:lang="en"><surname>Berezovskaya</surname><given-names>Tatyana Pavlovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сыченкова</surname><given-names>Наталия Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Sychenkova</surname><given-names>Nataliya Ivanovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Медицинский радиологический научный центр” Министерства здравоохранения России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Radiological Research Centre of the Russian Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2014</year></pub-date><volume>0</volume><issue>3</issue><fpage>124</fpage><lpage>134</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прошина Ю.В., Прошин А.А., Березовская Т.П., Сыченкова Н.И., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Прошина Ю.В., Прошин А.А., Березовская Т.П., Сыченкова Н.И.</copyright-holder><copyright-holder xml:lang="en">Proshina Y.V., Proshin A.A., Berezovskaya T.P., Sychenkova N.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/57">https://medvis.rdsmedia.ru/jour/article/view/57</self-uri><abstract><p>Цель исследования: определить возможности дифференциальной диагностики опухолей яичников, выявленных при МРТ-стадировании рака тела матки (РТМ). Материал и методы. МРТ-стадирование на 1,5 Тл МР-томографе выполнено 131 больной РТМ, 15 из которых с выявленными опухолями яичников включены в дальнейшее сравнительное исследование клиниколабораторных и МРТ-характеристик. По данным гистологического исследования метастатическое поражение яичников (стадия IIIA FIGO) установлено у 7 (5,3%), синхронный рак яичников (РЯ) - у 6 (4,6%), синхронные стромальные опухоли яичников - у 2 (1,5%) больных (в том числе фибросаркома). Результаты. Синхронный и метастатический РЯ преимущественно характеризовался кистозно-солидной структурой в отличие от солидного строения стромальных опухолей яичников. Выявлены тенденции к более раннему проявлению заболевания, большим размерам опухолей яичников и их двустороннему поражению по данным МРТ при синхронном РТМ и РЯ. При метастатическом поражении яичников чаще определяли МР-признаки глубокой инвазии миометрия. Установлены статистически значимо более высокие уровни Са125 при метастатическом поражении яичников. Выводы. Несмотря на существующие различия в клинико-лабораторных и МР-характеристиках метастазов РТМ в яичники и синхронных опухолей яичников, для окончательного диагноза в большинстве случаев требуется гистологическая верификация.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To determine the possibilities of differential diagnostics of ovarian tumors revealed at MRI staging of cancer of the corpus uteri. Materials and methods. MRI staging using 1.5 T unit was performed in 131 patients with endometrial cancer 15 patients of this cohort had ovarian lesions and were included in further study with clinical, laboratory and MRI data analysis. Among them, metastatic ovarian lesions (FIGO stage IIIA) were histologically proved in 7 (5.3%) cases, synchronous ovarian carcinoma in 6 (4.6%) cases, synchronous stromal ovarian tumors in 2 (1.5%) patients (including one case of fibrosarcoma). Results. Synchronous and metastatic ovarian cancer showed predominantly cystic-and-solid structure, in contradistinction to solid stromal tumors. In cases of synchronous endometrial and ovarian cancer trends for early manifestation of the disease, larger ovarian lesions size and bilateral involvement were identified. Deep myometrial invasion of endometrial cancer was more specific for cases of metastatic lesions. Ca125 showed statistically significant higher values in cases of metastatic process. Conclusion. Despite of differences in clinical and MRI features of synchronous and metastatic ovarian tumors, histological verification is needed in most of cases for diagnosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>МРТ</kwd><kwd>рак тела матки</kwd><kwd>синхронные опухоли тела матки и яичников</kwd><kwd>фибросаркома яичника</kwd><kwd>MRI</kwd><kwd>cancer of the corpus uteri</kwd><kwd>synchronous tumors of corpus uteri and ovaries</kwd><kwd>ovarian fibrosarcoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2012 году (заболеваемость и смертность); Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: ФГБУ МНИОИ им. П.А. Герцена Минздрава России, 2014. 250 с.</mixed-citation><mixed-citation xml:lang="en">Злокачественные новообразования в России в 2012 году (заболеваемость и смертность); Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: ФГБУ МНИОИ им. П.А. Герцена Минздрава России, 2014. 250 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Паяниди Ю.Г., Сельчук В.Ю., Асанов А.Ю. и др. Роль молекулярно-генетических маркеров в дифференциальной диагностике синхронного эндометриоидного рака яичников и тела матки. Рос. биотер. журн. 2006; 1 (5): 71-74.</mixed-citation><mixed-citation xml:lang="en">Паяниди Ю.Г., Сельчук В.Ю., Асанов А.Ю. и др. Роль молекулярно-генетических маркеров в дифференциальной диагностике синхронного эндометриоидного рака яичников и тела матки. Рос. биотер. журн. 2006; 1 (5): 71-74.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Takeshima N., Hirai Y., Yang K. et al. Ovarian metastasis in endometrial carcinoma. Gynecol. Oncol. 1998; 70 (2): 183-187.</mixed-citation><mixed-citation xml:lang="en">Takeshima N., Hirai Y., Yang K. et al. Ovarian metastasis in endometrial carcinoma. Gynecol. Oncol. 1998; 70 (2): 183-187.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Soliman P.T., Slomovitz B.M., Broaddus R.R. et al. Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases. Gynecol. Oncol. 2004; 94: 456-462.</mixed-citation><mixed-citation xml:lang="en">Soliman P.T., Slomovitz B.M., Broaddus R.R. et al. Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases. Gynecol. Oncol. 2004; 94: 456-462.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ramus S.J., Elmasry K., Luo Z. et al. Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer. Clin. Cancer Res. 2008; 14: 5840-5548.</mixed-citation><mixed-citation xml:lang="en">Ramus S.J., Elmasry K., Luo Z. et al. Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer. Clin. Cancer Res. 2008; 14: 5840-5548.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Zaino R., Whitney C., Brady M.F. et al. Simultaneously detected endometrial and ovarian carcinoma - a prospective clinicopathologic study of 74 cases: a Gynecologic Oncology Group study. Gynecol. Oncol. 2001; 83: 355-362.</mixed-citation><mixed-citation xml:lang="en">Zaino R., Whitney C., Brady M.F. et al. Simultaneously detected endometrial and ovarian carcinoma - a prospective clinicopathologic study of 74 cases: a Gynecologic Oncology Group study. Gynecol. Oncol. 2001; 83: 355-362.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ulbright T.M., Roth L.M. Metastatc and independent cancers of the endometrium and ovary: a clinicopathologic study of 34 cases. Hum. Pathol. 1985; 16 (1): 28-34.</mixed-citation><mixed-citation xml:lang="en">Ulbright T.M., Roth L.M. Metastatc and independent cancers of the endometrium and ovary: a clinicopathologic study of 34 cases. Hum. Pathol. 1985; 16 (1): 28-34.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Walsh C., Holschneider C., Hoang Y. et al. Coexisting ovarian malignancy in young women with endometrial cancer. Obstet. Gynecol. 2005; 106: 693-699.</mixed-citation><mixed-citation xml:lang="en">Walsh C., Holschneider C., Hoang Y. et al. Coexisting ovarian malignancy in young women with endometrial cancer. Obstet. Gynecol. 2005; 106: 693-699.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Broeders F.M., van der Wurf A.A., Pijnenborg J.M., Vos M.C. Preoperative identification of synchronous ovarian and endometrial cancer: importance of appropriate workup. Int. J. Gynecol. Cancer. 2012; 22 (8): 1325-1331.</mixed-citation><mixed-citation xml:lang="en">Broeders F.M., van der Wurf A.A., Pijnenborg J.M., Vos M.C. Preoperative identification of synchronous ovarian and endometrial cancer: importance of appropriate workup. Int. J. Gynecol. Cancer. 2012; 22 (8): 1325-1331.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Willmott F., Allouni K.A., Rockall A. Radiological manifestations of metastasis to the ovary. J. Clin. Pathol. 2012; 65: 585-590.</mixed-citation><mixed-citation xml:lang="en">Willmott F., Allouni K.A., Rockall A. Radiological manifestations of metastasis to the ovary. J. Clin. Pathol. 2012; 65: 585-590.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Troiano R.N., Lazzarini K.M., Skoutt L.M. Fibroma and fibrothecoma of the ovary: MR imaging findings. Radiology. 1997; 204: 795-798.</mixed-citation><mixed-citation xml:lang="en">Troiano R.N., Lazzarini K.M., Skoutt L.M. Fibroma and fibrothecoma of the ovary: MR imaging findings. Radiology. 1997; 204: 795-798.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ray S., Biswas B.K., Mukhopadhyay S. Giant primary ovarian fibrosarcoma: Case report and review of pitfalls. J. Cytol. 2012; 29 (4): 255-257.</mixed-citation><mixed-citation xml:lang="en">Ray S., Biswas B.K., Mukhopadhyay S. Giant primary ovarian fibrosarcoma: Case report and review of pitfalls. J. Cytol. 2012; 29 (4): 255-257.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Швачко С.А., Грицай А.Н., Лазарева Н.И. и др. Саркомы яичников: обзор литературы. Опухоли женской репродуктивной системы. 2010; 3: 88-94.</mixed-citation><mixed-citation xml:lang="en">Швачко С.А., Грицай А.Н., Лазарева Н.И. и др. Саркомы яичников: обзор литературы. Опухоли женской репродуктивной системы. 2010; 3: 88-94.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
