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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-2017-6-130-139</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-497</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВЫЕ ТЕХНОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEW TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>Динамический фантом для моделирования потоков при МР-ангиографии</article-title><trans-title-group xml:lang="en"><trans-title>Dynamic Phantom for Flow Model in Magnetic Resonance Angiography</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петряйкин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petraikin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петряйкин Алексей Владимирович –  кандидат медицинских наук, доцент, врач-рентгенолог.</p><p>109029 Москва, ул. Средняя Калитниковская, д. 28, стр. 1, тел.: +7-916-156-46-22</p></bio><bio xml:lang="en"><p>Alexey V. Petraikin – cand. of med. sci, associate professor, senior researcher of Research and Practical Center of Medical Radiology of Department of Health Care of Moscow</p><p>28-1, Srednjaja Kalitnikovskaja str., 109029, Moscow, Phone: +7-916-156-4622</p></bio><email xlink:type="simple">alexeypetraikin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергунова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergunova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергунова Кристина Анатольевна – руководитель отдела разработки средств контроля и технического мониторинга.</p></bio><bio xml:lang="en"><p>Kristina A. Sergunova – head of Technical Monitoring &amp; QA Development Department.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenov</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенов Дмитрий Сергеевич – научный сотрудник отдела разработки средств контроля и технического мониторинга.</p></bio><bio xml:lang="en"><p>Dmitry S. Semenov – scientist researcher of Technical Monitoring &amp; QA Development Department.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахмад</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmad</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ахмад Екатерина Сергеевна – научный сотрудник отдела разработки средств контроля и технического мониторинга.</p></bio><bio xml:lang="en"><p>Ekaterina S. Ahmad – scientist researcher of Technical Monitoring &amp; QA Development.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ким</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kim</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ким Станислав Юрьевич –  кандидат медицинских наук, заместитель директора по науке.</p></bio><bio xml:lang="en"><p>Stanislav Yu. Kim – cand. of med. sci., deputy director for science.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Громов Александр Игоревич – доктор медицинских наук, профессор, главный научный сотрудник экспертного отдела.</p></bio><bio xml:lang="en"><p>Alexander I. Gromov – doct. of med. sci., Professor, senior researcher.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Сергей Павлович – доктор медицинских наук, профессор, директор.</p></bio><bio xml:lang="en"><p>Sergey P. Morozov – doct. of med. sci., Professor, director.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ “Научно-практический центр медицинской радиологии” Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Practical Center of Medical Radiology, Department of Health Care of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2017</year></pub-date><volume>0</volume><issue>6</issue><fpage>130</fpage><lpage>139</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петряйкин А.В., Сергунова К.А., Семенов Д.С., Ахмад Е.С., Ким С.Ю., Громов А.И., Морозов С.П., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Петряйкин А.В., Сергунова К.А., Семенов Д.С., Ахмад Е.С., Ким С.Ю., Громов А.И., Морозов С.П.</copyright-holder><copyright-holder xml:lang="en">Petraikin A.V., Sergunova K.A., Semenov D.S., Akhmad E.S., Kim S.Y., Gromov A.I., Morozov S.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/497">https://medvis.rdsmedia.ru/jour/article/view/497</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: разработать фантом для моделирования потоков при проведении магнитно-резонансной ангиографии (МРА) и оценки относительного контраста, погрешности определения линейной и объемной скорости потока. С использованием данного фантома сравнить томографы нескольких производителей в отношении эффективности проведения МРА-исследований.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Основная часть динамического фантома состоит из заполненного гелем диска и трех трубочек для моделирования потока жидкости. С использованием разработанного фантома были проведены эксперименты на МР-томографах двух фирм-производителей для сравнения количественных оценок (относительный контраст) МРА-последовательностей: 2DTOF, 3DTOF и на трех МР-томографах одной фирмы для оценки точности построения калибровочной кривой, определения линейной и объемной скорости по изображениям 2DPC.</p></sec><sec><title>Результаты</title><p>Результаты. Полученные результаты сканирования фантома в режимах 2Dи 3DTOF позволили сравнить результаты применения МРА-режимов для МР-томографов двух производителей. Для режима 2DTOF показано более эффективное усиление сигнала вследствие TOF-эффекта для томографа производителя 2 в сравнении с производителем 1 : 8,86 ± 0,88 и 6,07 ± 0,03 отн. ед. соответственно. Для режима 3DTOF значительно больший относительный контраст втекающей жидкости вследствие TOF-эффекта наблюдается у производителя 1 : 6,06 ± 0,47 и 3,17 ± 0,83 отн. ед. соответственно. Исследования на фантоме согласуются с результатами аналогичных измерений для пациентов. Максимальная относительная погрешность измерения линейной скорости движения жидкости в режиме 2DPC для трех томографов одного производителя составила 4%. Относительная погрешность измерения объемной скорости (потока) для сосудов диаметром 3 мм составила 0,9–1,8%. С помощью разработанного динамического фантома качественно были промоделированы эффекты МРА, связанные с усилением сигнала от “текущей” жидкости для режимов 3DPC и Time-SLIP.</p></sec><sec><title>Заключение</title><p>Заключение. Разработан динамический фантом для моделирования потока при МРА. Задаваемый ток жидкости с линейным профилем скоростей позволяет определить точность измерения линейной и объемной скорости потока в клинических условия, оценить необходимость их коррекции относительно неподвижных тканей при использовании последовательности 2DPC, оценить эффективность визуализации сосудистого русла.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose. To develop phantom for flow modeling in magnetic resonance angiography (MRA): relative contrast assessment, accuracy of the linear velocity and volumetric flow, what improve accuracy of diagnostic in cardiac and neurosurgical clinics (quality assessment of blood and cerebrospinal fluid motion). To compare scanners of different manufactures in points of the MRA efficiency using the developed phantom.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The main part of dynamic phantom consists of a disc filled with agarose gel (for linear and volumetric velocity control) and silicone tubes for fluid flow modelling. MR study was performed at MRI units of two manufactures for comparing quantitative assessments of MRA sequences: 2DTOF, 3DTOF, and at three MRI units of one firm for estimated accuracy calibration curve calculating and linear velocity and volumetric flow determination for PC MRA. Phantom study well correlate with clinical MRA results.</p></sec><sec><title>Results</title><p>Results. Obtained phantom scanning results in 2DTOF, 3DTOF sequences allow for objective comparing two MRI units of different manufactures. For 2DTOF mode was showed more effective signal enhancement affected by TOF effect for scanner of manufacture 2, then manufacture 1: 8.86 ± 0.88 и 6.07 ± 0.03 corresponding. For 3DTOF was observed rather more inflow relative contrast affected by TOF effect for scanner of manufacture 1: 6.06 ± 0.47 and 3.17 ± 0.83 corresponding. However, for manufacture 1 was showed more significant signal suppression for fat tissue, which improve vasculature visualization. Accuracy linear velocity fluid flow measurement in 2DPC is equal to ±2σ = ±0,4 by five pixels for three scanners of one manufacture. Using developed phantom was modelled MRA effects in 3DPC and Time-SLIP modes.</p></sec><sec><title>Conclusions</title><p>Conclusions. The developed dynamic phantom can be used for calibration tests in MRA. The case of MRI units of two manufactures were compared quantitative assessments of MRA sequences and analyzed methods of enhancement fluid flow signal.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография</kwd><kwd>МРТ</kwd><kwd>магнитно-резонансная ангиография</kwd><kwd>МРА</kwd><kwd>фантомы для контроля изображений</kwd><kwd>вращающийся дисковый фантом</kwd><kwd>контроль качества</kwd><kwd>тестовые испытания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>magnetic resonance imaging</kwd><kwd>MRI</kwd><kwd>magnetic resonance angiography</kwd><kwd>MRA</kwd><kwd>angiography MRI</kwd><kwd>imaging phantom</kwd><kwd>rotating disc phantom</kwd><kwd>quality control</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Koktzoglou I., Giri S., Piccini D., Grodzki D.M., Flanagan O., Murphy I.G, Gupta N., Collins J.D., Edelman R.R. 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