medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.10.24835/1607-0763-2017-2-53-59medvis-392Research ArticleБРЮШНАЯ ПОЛОСТЬ И ЗАБРЮШИННОЕ ПРОСТРАНСТВОABDOMEN AND RETROPERITONEALЭластометрия печени с применением форсированного импульса акустической радиации (ARFI-эластометрия) у здоровых лиц в покое, после физической и пищевой нагрузокAcoustic Radiation Force Impulse Elastometry (ARFI Elastometry) of the Liver in Normal Subjects, after Food Intake and Physical EffortМегроянА. А.MegroyanA. A.

Мегроян Алина Алексановна – врач ультразвуковой диагностики лаборатории ультразвуковой диагностики 

Для корреспонденции: 119991 Москва, Абрикосовский пер., д. 2.

Alina A. Megroyan – doctor of ultrasound diagnostics 

Contact: 119991 Moscow, Abrikosovskii per., 2.

alinamegroyan@gmail.comКамаловЮ. Р.KamalovJu. R.

Камалов Юлий Рафаэльевич – доктор медицинских наук, заведующий лабораторией ультразвуковой диагностики

Москва

Julius R. Kamalov – doct.. of med. sci., head of ultrasound diagnostics

Moscow

КрыжановскаяЕ. Ю.KrizhanovskayaE. Ju.

Крыжановская Евгения Юрьевна – кандидат медицинских наук, старший научный сотрудник лаборатории ультразвуковой диагностики

Москва

Evgeniya U. Krizhanovskaya – cand. of med. sci., senior research assistant of ultrasound diagnostics

Moscow

ФилинА. В.FilinA. V.

Филин Андрей Валерьевич – доктор медицинских наук, заведующий отделением пересадки печени

Москва

Andrei V. Filin – doct. of med. sci., head of department of liver transplantation

Moscow

ФГБНУ “Российский научный центр хирургии им. акад. Б.В. Петровского”РоссияB.V. Petrovsky National Research Centre of SurgeryRussian Federation201728042017025359Copyright © Мегроян А.А., Камалов Ю.Р., Крыжановская Е.Ю., Филин А.В., 20172017Мегроян А.А., Камалов Ю.Р., Крыжановская Е.Ю., Филин А.В.Megroyan A.A., Kamalov J.R., Krizhanovskaya E.J., Filin A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.rdsmedia.ru/jour/article/view/392

Цель исследования: определить показатели эластометрии с применением форсированного импульса акустической радиации (ARFI-эластометрия) в норме, после пищевой и физической нагрузок.Материал и методы. ARFI-эластометрия печени была выполнена у 32 здоровых пациентов (20 (62,5%) добровольцев и 12 (37,5%) потенциальных доноров фрагмента печени). Средний возраст пациентов составил 26,9 ± 5,3 года. Исследование выполняли строго натощак по межреберьям справа при задержке дыхания на фоне неглубокого вдоха в положении лежа на спине с отведенной правой рукой за голову. Эластометрию паренхимы печени 20 добровольцам также выполняли через 30 мин после пищевой нагрузки (калорийность которой составила 350 ккал) и на следующий день непосредственно после физической нагрузки (20 приседаний). Использовали диагностическую систему Siemens Acuson S2000 и широкополостный (1–6 МГц) конвексный датчик 6C1.Результаты. Значение жесткости паренхимы правой доли печени в норме у 32 пациентов составило 1,16 ± 0,12 м/с (95% ДИ 0,92 ± 1,38). У 20 пациентов значение жесткости печени натощак – 1,21 ± 0,09 м/с (95% ДИ 1,06 ± 1,38), через 30 мин после пищевой нагрузки – 1,22 ± 0,12 м/с (95% ДИ 1,01 ± 1,43) (р > 0,05). Физическая нагрузка не оказала достоверного влияния на жесткость печени (1,16 ± 0,12 м/с против 1,20 ± ± 0,07 м/с, р > 0,05).Выводы. Жесткость правой доли печени в норме – 1,16 ± 0,12 м/с (95% ДИ 0,92 ± 1,38). Пищевая и физическая нагрузки не оказывают достоверного влияния на показатели жесткости печени.

Purpose: the aim of this study was to assess the values of ARFI elastometry in normal subjects and effects of food intake and physical effort.Material and methods. ARFI elastometry measurements were done in 32 patients (20 (62.5%) volunteers and 12 (37.5%) potential liver fragment donors). Mean age of patients was 26.9 ± 5.3 years. The study was performed in fasting condition in right intercostals approach, while the patients were asked to stop normal breathing for a moment lying in supine position with the right hand placed above the head. For 20 volunteers ARFI elastometry was performed at 30 minutes after food intake (about 350 kcal) and at next day immediately after physical effort (20 squats). The study was performed using Siemens Acuson S2000 ultrasound system with a 6C1 transducer.Results. The stiffness of the right liver lobe in 32 healthy subjects was 1.16 ± 0.12 m/s (95% CI 0.92 ± 1.38), the mean liver stiffness values of 20 volunteers in fasting condition were 1,21±0,09 m/s (95% CI 1.06 ± 1.38), 30 minutes after the meal – 1.22 ± 0.12 m/s (95% CI 1.01 ± 1.43) (р > 0.05). Physical effort didn’t make significant influence on the liver stiffness measurements (1.16 ± 0.12 m/s vs 1.20 ± 0.07 m/s, р > 0.05).Conclusion. Liver stiffness value in healthy subjects was 1.16 ± 0.12 m/s (95% CI 0.92 ± 1.38). There was no significant influence of food intake and physical effort on the liver stiffness measurements.

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The authors declare that there are no conflicts of interest present.