medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.medvis-318Research ArticleКОНТРАСТНЫЕ СРЕДСТВАCONTRAST MEDIAКонтрастные средства для современной МСКТ: йоверсол - пути оптимизации использования и достижения максимального контрастного усиленияContrast Agents for MDCT Today: Ioversol - Ways to Optimize the Use and Maximize Contrast EnhancementКармазановскийГригорий ГригорьевичKarmazanovskyGrigory Grigorievichkarmazanovsky@ixv.ruФГБУ “Институт хирургии им. А.В. Вишневского” Министерства здравоохранения России; ГБОУ ВПО “Первый Московский государственный медицинский университет им. И.М. Сеченова” Министерства здравоохранения РоссииРоссияA.V. Vishnevsky Institute of Surgery; I.M. Sechenov First Moscow state medical universityRussian Federation20142812201406108118Copyright © Кармазановский Г.Г., 20142014Кармазановский Г.Г.Karmazanovsky G.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.rdsmedia.ru/jour/article/view/318

За последнее десятилетие в мировой периодике появились новые данные, посвященные сравнительной характеристике рентгеноконтрастных средств, широко применяемых в практической работе и научных исследованиях. Цель исследования: поскольку йоверсол по сути стал первым отечественным рентгеноконтрастным средством, представляет интерес оценить информацию о нем, имеющуюся в открытом доступе. Материал и методы. В широко известной поисковой системе PubMed по ключевым словам “ioversol” и “optiray” был проведен поиск научных публикаций с 2007 г. по настоящее время, в которых имелась обстоятельная информация об использовании этого диагностического средства при мультиспиральной томографии и ангиографии. Всего анализу подвергнуто 26 научных публикаций (как резюме статей, так и сами статьи (в доступных источниках)), в которых анализировались различные аспекты применения и характеристики йоверсола. Сведения объединены по группам. Результаты. Побочные реакции на контрастные вещества (КВ), оценка нефропатии, влияние КВ на кровь и ее элементы, сравнение различной концентрации КВ, уменьшение объема КВ при МСКТ-исследованиях, преднаполненные шприцы, инвазивные внутриартериальные вмешательства - по всем этим направлениям имеются публикации, в которых показана высокая надежность йоверсола. Выводы. Йоверсол относится к группе КВ, которые отлично зарекомендовали себя при лабораторных испытаниях и массовых клинических исследованиях. Это качественный и надежный рентгенодиагностический препарат, и он должен быть в арсенале диагностических средств отделений лучевой диагностики, кабинетов КТ.

Relevance of the topic. Over the last decade in the world, new data periodicals devoted to the comparative characteristics of widely used in practical work and scientific purposes radiopaque agents. The purpose of this work. Since loversol in essence became the first Russian radiopaque agent is of interest to evaluate the information about it available in the scientific sites. Materials and methods. In the well-known search system PubMed by keyword “ioversol” and “optiray” was searched scientific publications from 2007 to the present, in which there was extensive information about the use of this contrast media with multislice computed tomography and angiography. In this paper we analyze both abstracts and articles themselves (in the available sources). Total 26 publications that analyze different aspects of the application and features loversol was studied. Information combined in groups. The Results. Adverse events, contrast media induced nephropathy, the impact of CM on the blood and its components, the comparison of different concentrations of Cm, a decrease of volume CM for MDCT examinations, pre-filled syringes, invasive intra-arterial procedures - in all these areas there are publications which shows high reliability of Ioversol. Conclusion. Ioversol refers to a group of CM, which have perfectly profile of reliability in laboratory tests and clinical examinations. This is a high-quality and a reliable X-ray CM and it should be in the arsenal of diagnostic radiology department and CT rooms.

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The authors declare that there are no conflicts of interest present.