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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvis-213</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРЮШНАЯ ПОЛОСТЬ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMEN</subject></subj-group></article-categories><title-group><article-title>Гибридные технологии в определении функционирующего объема печени перед обширными резекциями</article-title><trans-title-group xml:lang="en"><trans-title>Hybrid Technology in Determining of Functioning Volume Liver Before Major Resection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабунин</surname><given-names>Алексей Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Shabunin</surname><given-names>Alexei Vasilevich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каралкин</surname><given-names>Анатолий Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Karalkin</surname><given-names>Anatoly Vasilievich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Греков</surname><given-names>Дмитрий Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Grekov</surname><given-names>Dmitry Nikolaevich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дроздов</surname><given-names>Павел Алексеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Drozdov</surname><given-names>Pavel Alexeevich</given-names></name></name-alternatives><email xlink:type="simple">dc.drozdov@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ДПО “Российская медицинская академия постдипломного образования” Минздрава России; ГБУЗ “Городская клиническая больница им. С.П. Боткина”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Russian Academia for Post-Graduate Education; S.P. Botkin City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ “Городская клиническая больница №1 им. Н.И. Пирогова”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.I. Pirogov City Clinical Hospital №1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ “Городская клиническая больница им. С.П. Боткина”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.P. Botkin City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2015</year></pub-date><volume>0</volume><issue>4</issue><fpage>39</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шабунин А.В., Каралкин А.В., Греков Д.Н., Дроздов П.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Шабунин А.В., Каралкин А.В., Греков Д.Н., Дроздов П.А.</copyright-holder><copyright-holder xml:lang="en">Shabunin A.V., Karalkin A.V., Grekov D.N., Drozdov P.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/213">https://medvis.rdsmedia.ru/jour/article/view/213</self-uri><abstract><p>Цель исследования: уменьшить процент острой пострезекционной печеночной недостаточности после обширных резекций. Материал и методы. С января 2013 г. больным, которым планировали удаление более 3 сегментов печени, кроме используемой компьютерной волюметрии печени, применяли ОФЭКТ/КТ печени с определением объема и преимущественного расположения функционирующей паренхимы печени по долям. В исследование вошло 24 больных. Выделили 2 группы больных. В первую группу вошли больные (n = 15; 62,5%), которых лечили до января 2013 г (ОФЭКТ/КТ печени не применяли), всем больным на первом этапе была выполнена предварительная химиоэмболизация правой ветви воротной вены. Во вторую группу вошли больные (n = 9; 37,5%), у которых в зависимости от данных КТ-волюметрии и наличия отягчающих факторов применяли дифференцированное лечение после интерпретации данных ОФЭКТ/КТ. Результаты. В первой группе радикально оперировано 9 больных. Острая послеоперационная печеночная недостаточность развилась у 1 больного, которую купировали на фоне проведения консервативной терапии (класс А). Во второй группе у больных FLR по результатам предоперационной волюметрии составил от 25 до 35%. У 5 больных объем функционирующей паренхимы печени в FLR был 30% и более, им выполнены резекции печени в следующем объеме: правосторонняя гемигепатэктомия расширенная (ПГГЭ) - 2, расширенная ПГГЭ - 2. У 4 больных объем функционирующей паренхимы в остающейся части был менее 30%, у этих больных был применен двухэтапный метод лечения. Радикально оперировано 3 больных: ПГГЭ - 2, расширенная ПГГЭ - 1. Признаков острой пострезекционной печеночной недостаточности в этой группе больных не было. Заключение. У больных с пограничной FLR применение ОФЭКТ/КТ печени позволяет дифференцированно выбрать тактику лечения и тем самым снизить вероятность развития пострезекционной острой печеночной недостаточности, снизить послеоперационную летальность и улучшить результаты лечения данной группы пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Aim: reduce the percentage of acute post-resection liver failure after major resection. Material and methods. From January 2013 patients who planned removal of more than 3 segments of the liver, in addition use computer liver volumetry used SPECT / CT of the liver with the definition of the scope and location of the pre-emptive functioning liver parenchyma on lobes. Identified two groups of patients. The first group included patients (n = 15) who were treated with up to January 2013 (SPECT/CT of the liver was not used), all patients in the first phase was completed preliminary portal vein embolisation (PVE). The second group included patients (n = 9), which, depending on the data of CT volumetry and the presence of precipitating factors to apply differential treatment when interpreting the data SPECT / CT. Results. In the first group of radical surgery in 9 patients. Acute postoperative hepatic failure occurred in one patient, who was stopped on a background of conservative therapy (Class A). In the second group of patients based on the results of pre FLR volumetry ranged from 25 to 35%. In 5 patients, the amount of functioning liver parenchyma in the FLR was 30% or more, they performed a liver resection: RHHE - 2 ERHHE - 2. In 4 patients the amount of functioning parenchyma in the remaining part was less than 30% of these patients has been applied a two-step method of treatment. Radical surgery in 3 patients: RHHE - 2 ERHHE - 1. Signs of acute post-resection liver failure in this group of patients was not. Conclusion. Patients with borderline FLR application of SPECT/CT allows differentiated liver choose the tactics of treatment and thereby reduce the likelihood of developing post-resection of acute liver failure, reduce postoperative mortality and improve treatment outcomes in this group of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метастатическое поражение печени</kwd><kwd>ОФЭКТ/КТ печени</kwd><kwd>резекция печени</kwd><kwd>liver metastases</kwd><kwd>SPECT/CT</kwd><kwd>hepatic resection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Manfredi S., Lepage C., Hatern C. et al. Epidemiology and management of liver metastases from colorectal cancer. Ann. Surg. 2006; 244 (2): 254-259.</mixed-citation><mixed-citation xml:lang="en">Manfredi S., Lepage C., Hatern C. et al. Epidemiology and management of liver metastases from colorectal cancer. Ann. 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