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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvis-187</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОНТРАСТНЫЕ СРЕДСТВА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CONTRAST MEDIA</subject></subj-group></article-categories><title-group><article-title>Применение эхоконтрастных препаратов в клинике и перспективы синхронизации УЗИ, КТ- и МРТ-изображений (собственный опыт и обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Application of Contrast Enhanced Ultrasound (Ceus) in the Clinic and Prospects of Synchronization Ultrasound, CT and MRI Images (Personal Experience and Literature Review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубарев</surname><given-names>Александр Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Zubarev</surname><given-names>Alexander Vasilievich</given-names></name></name-alternatives><email xlink:type="simple">zubarev@pmc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фёдорова</surname><given-names>Анна Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorova</surname><given-names>Anna Aleksandrovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернышев</surname><given-names>Владимир Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Chernishev</surname><given-names>Vladimir Vladimirovich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Варламов</surname><given-names>Геннадий Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Varlamov</surname><given-names>Gennadiy Vladimirovich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Нина Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>Nina Andreevna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федорова</surname><given-names>Наталья Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorova</surname><given-names>Natalya Aleksandrovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Учебно-научный медицинский центр” Управления делами Президента РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>President Educational Medical Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ “Учебно-научный медицинский центр” Управления делами Президента РФ; ЗД КДЦ “Медси”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>President Educational Medical Center; CDZ “Medsi”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2015</year></pub-date><volume>0</volume><issue>1</issue><fpage>94</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зубарев А.В., Фёдорова А.А., Чернышев В.В., Варламов Г.В., Соколова Н.А., Федорова Н.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Зубарев А.В., Фёдорова А.А., Чернышев В.В., Варламов Г.В., Соколова Н.А., Федорова Н.А.</copyright-holder><copyright-holder xml:lang="en">Zubarev A.V., Fedorova A.A., Chernishev V.V., Varlamov G.V., Sokolova N.A., Fedorova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/187">https://medvis.rdsmedia.ru/jour/article/view/187</self-uri><abstract><p>Лучевая диагностика играет важную роль в первичной диагностике различных онкологических заболеваний. Постоянное развитие и совершенствование ультразвукового метода заставляет нас уделять все больше внимания появляющимся новым технологиям, чтобы своевременно внедрять их в клиническую практику. В предлагаемой работе мы постарались осветить основные аспекты и возможности применения эхоконтрастных препаратов, а также возможность синхронизации УЗИ, КТ- и МРТ-изображений. Представлены классификация, физические принципы и основные типы эхоконтрастных препаратов, подробно описана методология выполнения УЗИ с контрастированием, приведены наиболее значимые преимущества и недостатки этой методики и собственные клинические наблюдения. Особенно перспективным представляется синхронизация КТ- и МРТ-изображений с контрастными ультразвуковыми изображениями, когда имеется возможность использовать преимущества эхоконтрастирования и избежать неблагоприятного влияния дополнительной лучевой нагрузки, введения йод- и гадолинийсодержащих препаратов. Несомненно, использование эхоконтрастирования открывает новые горизонты в ультразвуковой диагностике, позволяя повысить ее эффективность и информативность, предоставляя во многом уникальную диагностическую информацию.</p></abstract><trans-abstract xml:lang="en"><p>Radioology plays a primary role in the diagnosis of various cancer diseases. Continuous development and improvement of ultrasound method compels us pay more attention to emerging new technologies, in order to timely implement them in clinical practice. In the present article we have tried to highlight the main aspects and possible applications echo contrast agents, as well as the ability to synchronize ultrasound, CT and MRI images. In the current article are described classification, physical principles and the basic types of echo contrast agents (ECA), the methodology of performing ultrasound study with contrast agents, the most important advantages and disadvantages of this technique and our own clinical observations. Especially promising is the synchronization of CT and MRI images with contrast ultrasound images when there is an opportunity to take advantage of CEUS and avoid the adverse effects of the additional radiation exposure, and introduction of iodine and gadolinium-containing agents. Undoubtedly, the use of ehokontrastirovaniya opens new horizons in ultrasound diagnostics, allowing to increase its effectiveness and informativity, providing a largely unique diagnostic information.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эхоконтрастные препараты</kwd><kwd>ультразвуковое исследование</kwd><kwd>компьютерная и магнитнорезонансная томография</kwd><kwd>contrast enhancement</kwd><kwd>ultrasound</kwd><kwd>CT</kwd><kwd>MRI</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Фомина С.В., Завадовская В.Д., Юсубов М.С. и др. Контрастные препараты для ультразвукового исследования. 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