medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.medvis-164Research ArticleБРЮШНАЯ ПОЛОСТЬABDOMENДиагностика билиарных структур с помощью магнитно-резонансной холангиографии у пациентов после трансплантации печениUse of Magnetic Resonance Cholangiography in Biliary Strictures Detection in Patients after Liver TransplantationАхметовЕрмек АбибуллаевичAkhmetovYermek Abibullaevichnoemail@neicon.ruСахишевЕржан МухадиновичSakhishevYerzhan Mukhadinovichnoemail@neicon.ruНациональный научный центр онкологии и трансплантологииРоссияNational Scientific Center of Oncology and TransplantologyRussian Federation201528122015066165Copyright © Ахметов Е.А., Сахишев Е.М., 20152015Ахметов Е.А., Сахишев Е.М.Akhmetov Y.A., Sakhishev Y.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.rdsmedia.ru/jour/article/view/164

Послеоперационные билиарные осложнения, частота которых варьирует в пределах 15-20%, являются одной из важных проблем после проведения трансплантации печени. Настоящий краткий обзор является попыткой суммировать данные литературы касательно основных видов билиарных стриктур, причин их возникновения, а также своевременного выявления таких осложнений с помощью магнитно-резонансной томографии. Приведены ключевые моменты применения магнитно-резонансной холангиографии у пациентов, перенесших трансплантацию печени. Отмечены показания к использованию метода и диагностическая ценность методики у пациентов данной группы.

Postoperative biliary complications with the rate of 15-20% of cases remain the important problem in patients after liver transplantation. The presented brief review is an attempt to summarize the data of literature regarding to the main types of strictures, their causes, and their adequate detection by magnetic resonance imaging. The key moments of the use of magnetic resonance cholangiography in patients after liver transplantationare described. Detailed attention have been done to the indications and diagnostic value of the method in this group of patients.

трансплантация печенибилиарные стриктурымагнитно-резонансная холангиопанкреатографияliver transplantationbiliary stricturesmagnetic resonance cholangiopancreatographyReferencesFulcher A., Turner M. Orthotopic liver transplantation: evaluation with MR cholangiography. Radiology. 1999; 211: 715-722.Fulcher A., Turner M. Orthotopic liver transplantation: evaluation with MR cholangiography. Radiology. 1999; 211: 715-722.Verdonk R., Buis C., Porte R. et al. Biliary complications after liver transplantation: a review. Scand. J. Gastroenterol. 2006; Suppl. 1: 89-101.Verdonk R., Buis C., Porte R. et al. Biliary complications after liver transplantation: a review. Scand. J. Gastroenterol. 2006; Suppl. 1: 89-101.Fulcher A., Turner M., Capps G. MR cholangiography: technical advances and clinical applications. Radiographics.1999; 19: 25-41.Fulcher A., Turner M., Capps G. MR cholangiography: technical advances and clinical applications. Radiographics.1999; 19: 25-41.Gopal D.V., Pfau P.R., Lucey M.R. Endoscopic management of biliary complications after orthotopic liver transplantation. Curr. Treat. Options Gastroenterol. 2003; 6: 509-515.Gopal D.V., Pfau P.R., Lucey M.R. Endoscopic management of biliary complications after orthotopic liver transplantation. Curr. Treat. Options Gastroenterol. 2003; 6: 509-515.Zhu Z., Rao W., Sun J. et al. Liver retransplantation for ischemic-type biliary lesions after orthotopic liver transplantation: a clinical report of 66 cases. Hepatobiliary Pancreat. Dis. Int. 2008; 7: 471-475.Zhu Z., Rao W., Sun J. et al. Liver retransplantation for ischemic-type biliary lesions after orthotopic liver transplantation: a clinical report of 66 cases. Hepatobiliary Pancreat. Dis. Int. 2008; 7: 471-475.Iwamoto H., Hama K., Nakamura Y. et al. Biliary complications after 52 adult living donor liver transplantations: a single-center experience. Transplant. Proc. 2008; 40: 2539-2541.Iwamoto H., Hama K., Nakamura Y. et al. Biliary complications after 52 adult living donor liver transplantations: a single-center experience. Transplant. Proc. 2008; 40: 2539-2541.Imanieh M., Erjaee A., Dehghani S. et al. Early postoperative complications of pediatric liver transplantation. Indian Pediatr. 2009; 46: 1088-1090.Imanieh M., Erjaee A., Dehghani S. et al. Early postoperative complications of pediatric liver transplantation. Indian Pediatr. 2009; 46: 1088-1090.Wojcicki M., Milkiewicz P., Silva M. Biliary tract complications after liver transplantation: a review. Dig. Surg. 2008; 25: 245-257.Wojcicki M., Milkiewicz P., Silva M. Biliary tract complications after liver transplantation: a review. Dig. Surg. 2008; 25: 245-257.Pascher A., Neuhaus P. Bile duct complications after liver transplantation. Transplant. Int. 2005; 18: 627-642.Pascher A., Neuhaus P. Bile duct complications after liver transplantation. Transplant. Int. 2005; 18: 627-642.Kaltenthaler E., Walters S., Chilcott J. MRCP compared to diagnostic ERCP for diagnosis when biliary obstruction is suspected: a systematic review. BMC Med. Imaging. 2006; 6: 9-24.Kaltenthaler E., Walters S., Chilcott J. MRCP compared to diagnostic ERCP for diagnosis when biliary obstruction is suspected: a systematic review. BMC Med. Imaging. 2006; 6: 9-24.Lomas D., Bearcroft P., Gimson A. MR cholangiopancreatography: prospective comparison of a breathhold 2D projection technique with diagnostic ERCP. Eur. Radiol. 1999; 9: 1411-1417.Lomas D., Bearcroft P., Gimson A. MR cholangiopancreatography: prospective comparison of a breathhold 2D projection technique with diagnostic ERCP. Eur. Radiol. 1999; 9: 1411-1417.Moser M., Wall W. Management of biliary problems after liver transplantation. Liver Transplant. 2001; Suppl.1: 46-52.Moser M., Wall W. Management of biliary problems after liver transplantation. Liver Transplant. 2001; Suppl.1: 46-52.Taylor A., Little A., Hennessy O. et al. Prospective assessment of magnetic resonance cholangio pancreatography for noninvasive imaging of the biliary tree. Gastrointest. Endosc. 2002; 55: 17-22.Taylor A., Little A., Hennessy O. et al. Prospective assessment of magnetic resonance cholangio pancreatography for noninvasive imaging of the biliary tree. Gastrointest. Endosc. 2002; 55: 17-22.Park D., Kim M., Lee S.S. et al. Accuracy of magnetic resonance holangiopancreatography for locating hepatolithiasis and detecting accompanying biliary strictures. Endoscopy. 2004; 36: 987-992.Park D., Kim M., Lee S.S. et al. Accuracy of magnetic resonance holangiopancreatography for locating hepatolithiasis and detecting accompanying biliary strictures. Endoscopy. 2004; 36: 987-992.Franco J. Biliary complications in liver transplant recipients. Curr. Gastroenterol. Rep. 2005; 7: 160-164.Franco J. Biliary complications in liver transplant recipients. Curr. Gastroenterol. Rep. 2005; 7: 160-164.Kim J., Lee J., Han J. et al. Contrast-enhanced MRI combined with MR cholangiopancreatography for the evaluation of patients with biliary strictures: differentiation of malignant from benign bile duct strictures. J. Magn. Reson. Imaging. 2007; 26: 304-312.Kim J., Lee J., Han J. et al. Contrast-enhanced MRI combined with MR cholangiopancreatography for the evaluation of patients with biliary strictures: differentiation of malignant from benign bile duct strictures. J. Magn. Reson. Imaging. 2007; 26: 304-312.Nandalur K., Hussain H., Weadock W. et al. Possible biliary disease: diagnostic performance of high-spatialresolution isotropic 3D T2-weighted MRCP. Radiology. 2008; 249: 883-890.Nandalur K., Hussain H., Weadock W. et al. Possible biliary disease: diagnostic performance of high-spatialresolution isotropic 3D T2-weighted MRCP. Radiology. 2008; 249: 883-890.Hekimoglu K., Ustundag Y., Dusak A. et al. MRCP vs. ERCP in the evaluation of biliary pathologies: review of current literature. J. Dig. Dis. 2008; 9: 162-169.Hekimoglu K., Ustundag Y., Dusak A. et al. MRCP vs. ERCP in the evaluation of biliary pathologies: review of current literature. J. Dig. Dis. 2008; 9: 162-169.McMahon C. The relative roles of magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound in diagnosis of common bile duct calculi: a critically appraised topic. Abdom. Imaging. 2008; 33: 6-9.McMahon C. The relative roles of magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound in diagnosis of common bile duct calculi: a critically appraised topic. Abdom. Imaging. 2008; 33: 6-9.Gor N., Levy R., Ahn J. Biliary cast syndrome following liver transplantation: Predictive factors and clinical outcomes. Liver Transplant. 2008; 14: 1466-1472.Gor N., Levy R., Ahn J. Biliary cast syndrome following liver transplantation: Predictive factors and clinical outcomes. Liver Transplant. 2008; 14: 1466-1472.Kinner S., Dechêne A., Susanne C. et al. Comparison of different MRCP techniques for the depiction of biliary complications after liver transplantation. Eur. Radiol. 2010; 20: 1749-1756.Kinner S., Dechêne A., Susanne C. et al. Comparison of different MRCP techniques for the depiction of biliary complications after liver transplantation. Eur. Radiol. 2010; 20: 1749-1756.Irie H., Honda H., Kuroiwa T. et al. Pitfalls in MR cholangiopancreatographic interpretation. Radiographics. 2001; 21: 23-37.Irie H., Honda H., Kuroiwa T. et al. Pitfalls in MR cholangiopancreatographic interpretation. Radiographics. 2001; 21: 23-37.Jagannath S., Kalloo A. Biliary complications after liver transplantation. Gastroenterology. 2002; 5: 101-102.Jagannath S., Kalloo A. Biliary complications after liver transplantation. Gastroenterology. 2002; 5: 101-102.Kamel I., Erbay N., Warmbrand G. et al. Liver regeneration after living adult right lobe transplantation. Abdom. Imaging. 2003; 28: 53-57.Kamel I., Erbay N., Warmbrand G. et al. Liver regeneration after living adult right lobe transplantation. Abdom. Imaging. 2003; 28: 53-57.Federle M., Kapoor V. Complications of liver transplantation: imaging and intervention. Radiol. Clin. N. Am. 2003; 41: 1289-1305.Federle M., Kapoor V. Complications of liver transplantation: imaging and intervention. Radiol. Clin. N. Am. 2003; 41: 1289-1305.Giacomoni A., Lauterio A., Slim A. et al. Biliary complications after living donor adult liver transplantation. Transplant. Int. 2006; 19 (6): 466-73.Giacomoni A., Lauterio A., Slim A. et al. Biliary complications after living donor adult liver transplantation. Transplant. Int. 2006; 19 (6): 466-73.Yersiz H., Cameron A., Carmody I. et al. Split liver transplantation. Transplant. Proc. 2006; 38: 602-603.Yersiz H., Cameron A., Carmody I. et al. Split liver transplantation. Transplant. Proc. 2006; 38: 602-603.Gemmete J., Mueller G., Carlos R. Liver transplantation in adults: postoperative imaging evaluation and interventional management of complications. Semin. Roentgenol. 2006; 41: 36-44.Gemmete J., Mueller G., Carlos R. Liver transplantation in adults: postoperative imaging evaluation and interventional management of complications. Semin. Roentgenol. 2006; 41: 36-44.Thuluvath P., Atassi T. Lee J. An endoscopic approach to biliary complications following orthotopic liver transplantation. Liver Int. 2003; 23:156-162.Thuluvath P., Atassi T. Lee J. An endoscopic approach to biliary complications following orthotopic liver transplantation. Liver Int. 2003; 23:156-162.Uzochukwu L., Bluth E., Smetherman D. et al. Early postoperative hepatic sonography as a predictor of vascular and biliary complications in adult orthotopic liver transplant patients. Am. J. Roentgenol. 2005; 185: 1558-1570.Uzochukwu L., Bluth E., Smetherman D. et al. Early postoperative hepatic sonography as a predictor of vascular and biliary complications in adult orthotopic liver transplant patients. Am. J. Roentgenol. 2005; 185: 1558-1570.Kawachi S., Shimazu M., Wakabayashi G. et al. Biliary complications in adult living donor liver transplantation with ductto-duct hepaticocholedochostomy or Roux-en-Y hepaticojejunostomy biliary reconstruction. Surgery. 2002; 132: 48-56.Kawachi S., Shimazu M., Wakabayashi G. et al. Biliary complications in adult living donor liver transplantation with ductto-duct hepaticocholedochostomy or Roux-en-Y hepaticojejunostomy biliary reconstruction. Surgery. 2002; 132: 48-56.Qian Y., Liu C., Lo C. et al. Risk factors for biliary complications after liver transplantation. Arch. Surg. 2004; 139:1101-1105.Qian Y., Liu C., Lo C. et al. Risk factors for biliary complications after liver transplantation. Arch. Surg. 2004; 139:1101-1105.Girometti R., Cereser L., Como G. et al. Biliary complications after orthotopic liver transplantation: MRCP findings. Abdom. Imaging. 2008; 33: 542-554.Girometti R., Cereser L., Como G. et al. Biliary complications after orthotopic liver transplantation: MRCP findings. Abdom. Imaging. 2008; 33: 542-554.Zamboni G., Pedrosa I., Kruskal J., Raptopoulos V. Multimodality postoperative imaging of liver transplantation. Eur. Radiol. 2008; 18: 882-891.Zamboni G., Pedrosa I., Kruskal J., Raptopoulos V. Multimodality postoperative imaging of liver transplantation. Eur. Radiol. 2008; 18: 882-891.Seehofer D., Eurich D., Veltzke-Schlieker W., Neuhaus P. Biliary Complications After Liver Transplantation: Old Problems and New Challenges. Am. J. Transplant. 2013; 13: 253-265.Seehofer D., Eurich D., Veltzke-Schlieker W., Neuhaus P. Biliary Complications After Liver Transplantation: Old Problems and New Challenges. Am. J. Transplant. 2013; 13: 253-265.

The authors declare that there are no conflicts of interest present.