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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1590</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1590</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРЮШНАЯ ПОЛОСТЬ И ЗАБРЮШИННОЕ ПРОСТРАНСТВО</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMEN AND RETROPERITONEAL</subject></subj-group></article-categories><title-group><article-title>Диагностические возможности магнитно-резонансной томографии в дифференциальной диагностике феохромоцитомы надпочечников</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostic capabilities of magnetic resonance imaging in the differential diagnosis of adrenal pheochromocytoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6758-5918</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайриева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khairieva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хайриева Ангелина Владимировна – врач-рентгенолог ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России ФГБУ “НМИЦ эндокринологии им. академика И.И. Дедова ” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0000-0002-6758-5918" ext-link-type="uri">https://orcid.org/0000-0002-6758-5918</ext-link>E-mail: komarito@mail.ru</p></bio><bio xml:lang="en"><p>Angelina V. Khairieva – Radiologist, National Medical Research Center of Endocrinology, Moscow<ext-link xlink:href="https://orcid.org/0000-0002-6758-5918" ext-link-type="uri">https://orcid.org/0000-0002-6758-5918</ext-link>E-mail: komarito@mail.ru</p></bio><email xlink:type="simple">komarito@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7965-9454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарбаева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarbaeva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарбаева Наталья Викторовна – канд. мед. наук, руководитель референс-центра лучевых методов диагностики, заведующая отделением компьютерной и магнитно-резонансной томографии ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России ФГБУ “НМИЦ эндокринологии им. академика И.И. Дедова ” Минздрава России, Москваhttps://orcid.org/ 0000-0001-7965-9454E-mail: ntarbaeva@inbox.ru </p></bio><bio xml:lang="en"><p>Natalia V. Tarbaevа – Cand. of Sci. (Med.), Head of the Reference-center of Radiation Diagnostic Methods, Head of the Department of Computer and Magnetic Resonance Imaging, National Medical Research Center of Endocrinology, Moscowhttps://orcid.org/ 0000-0001-7965-9454E-mail: ntarbaeva@inbox.ru</p></bio><email xlink:type="simple">ntarbaeva@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-8035-676X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манаев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Manaev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Манаев Алмаз Вадимович – медицинский физик ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России ФГБУ “НМИЦ эндокринологии им. академика И.И. Дедова ” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0009-0003-8035-676X" ext-link-type="uri">https://orcid.org/0009-0003-8035-676X</ext-link>E-mail: a.manaew2016@yandex.ru </p></bio><bio xml:lang="en"><p>Almaz V. Manaev – Medical physicist, National Medical Research Center of Endocrinology, Moscow<ext-link xlink:href="https://orcid.org/0009-0003-8035-676X" ext-link-type="uri">https://orcid.org/0009-0003-8035-676X</ext-link>E-mail: a.manaew2016@yandex.ru</p></bio><email xlink:type="simple">a.manaew2016@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трошина Екатерина Анатольевна – член-корр. РАН, доктор мед. наук, профессор, заместитель директора Центра, директор Института клинической эндокринологии ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России ФГБУ “НМИЦ эндокринологии им. академика И.И. Дедова ” Минздрава России, Москваhttps://orcid.org/<ext-link xlink:href="https://orcid.org/0000-0002-8520-8702;" ext-link-type="uri">0000-0002-8520-8702</ext-link>E-mail: troshina@inbox.ru </p></bio><bio xml:lang="en"><p>Ekaterina A. Troshina – Corresponding Member of the Russian Academy of Sciences, Doct. of Sci. (Med.), Professor, Deputy Director, Director of the Сlinical endocrinology institute, National Medical Research Center of Endocrinology, Moscowhttps://orcid.org/<ext-link xlink:href="https://orcid.org/0000-0002-8520-8702;" ext-link-type="uri">0000-0002-8520-8702</ext-link>E-mail: troshina@inbox.ru</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5634-7877</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельниченко</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnichenko</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мельниченко Галина Афанасьевна – академик РАН, доктор мед. наук, профессор, заместитель директора Центра по научной работе ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России ФГБУ “НМИЦ эндокринологии им. академика И.И. Дедова ” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0000-0002-5634-7877" ext-link-type="uri">https://orcid.org/0000-0002-5634-7877</ext-link>e-mail: teofrast2000@mail.ru</p></bio><bio xml:lang="en"><p>Galina A. Melnichenko – Full Member of the Russian Academy of Sciences, Doct. of Sci. (Med.), Professor, Deputy director for Research, National Medical Research Center of Endocrinology, Moscow<ext-link xlink:href="https://orcid.org/0000-0002-5634-7877" ext-link-type="uri">https://orcid.org/0000-0002-5634-7877</ext-link>e-mail: teofrast2000@mail.ru</p></bio><email xlink:type="simple">teofrast2000@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9717-9742</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мокрышева</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Mokrysheva</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мокрышева Наталья Георгиевна – академик РАН, доктор мед. наук, профессор, директор Центра, заведующая кафедрой персонализированной и трансляционной медицины, научный руководитель отделения патологии околощитовидных желез и нарушений минерального обмена ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России ФГБУ “НМИЦ эндокринологии им. академика И.И. Дедова ” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0000-0002-9717-9742" ext-link-type="uri">https://orcid.org/0000-0002-9717-9742</ext-link>E-mail: mokrisheva.natalia@endocrincentr.ru </p></bio><bio xml:lang="en"><p>Natalia G. Mokrysheva – Full Member of the Russian Academy of Sciences, Doct of Sci. (Med.), Professor; Director of the Center, Head of the Department of Personalized and Translational Medicine, Scientific Director of the Department of Pathology of the Parathyroid Glands and Disorders of Mineral Metabolism, National Medical Research Center of Endocrinology, Moscow<ext-link xlink:href="https://orcid.org/0000-0002-9717-9742" ext-link-type="uri">https://orcid.org/0000-0002-9717-9742</ext-link>E-mail: mokrisheva.natalia@endocrincentr.ru</p></bio><email xlink:type="simple">mokrisheva.natalia@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГНЦ РФ  ФГБУ “Национальный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова ” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Endocrinology of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2026</year></pub-date><volume>30</volume><issue>1</issue><fpage>41</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хайриева А.В., Тарбаева Н.В., Манаев А.В., Трошина Е.А., Мельниченко Г.А., Мокрышева Н.Г., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Хайриева А.В., Тарбаева Н.В., Манаев А.В., Трошина Е.А., Мельниченко Г.А., Мокрышева Н.Г.</copyright-holder><copyright-holder xml:lang="en">Khairieva A.V., Tarbaeva N.V., Manaev A.V., Troshina E.A., Melnichenko G.A., Mokrysheva N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1590">https://medvis.rdsmedia.ru/jour/article/view/1590</self-uri><abstract><sec><title>Введение</title><p>Введение. Дифференциальная диагностика феохромоцитомы и аденомы надпочечника крайне важна для определения тактики ведения пациента и планирования оперативного вмешательства. Лабораторных показателей и данных компьютерной томографии в ряде случаев недостаточно для постановки точного диагноза. В нашем исследовании мы стремились оценить возможности магнитно-резонансной томографии в диагностике феохромоцитомы надпочечников.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: оценка возможностей использования мультипараметрической магнитно-резонансной томографии в дифференциальной диагностике феохромоцитомы надпочечников.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 69 пациентов с образованиями надпочечников, которым впоследствии выполнялось хирургическое вмешательство по поводу клинически злокачественного потенциала опухоли или ее гормональной активности. Всем пациентам проводилась мультипараметрическая магнитно-резонансная томография. В рамках постобработки оценивалась интенсивность сигнала образований надпочечников на различных сериях, проводился расчет индексов интенсивности сигнала от образований, в том числе в сравнении с селезенкой и мышцами, для оценки различий этих показателей у феохромоцитом и других образований надпочечников.</p></sec><sec><title>Результаты</title><p>Результаты. Для феохромоцитом характерны следующие пороговые значения: индекс интенсивности сигнала от образования на Т2-ВИ по сравнению с мышцами (T2 index) &gt; 2,630, индекс интенсивности сигнала от образования в режиме двойного эхо (SI index) &lt; 16,600, индекс химического сдвига по сравнению с селезенкой (ASR) &gt; 0,840.</p></sec><sec><title>Заключение</title><p>Заключение. Каждый из исследованных параметров имел ряд исключений и ограничений, поэтому результаты данного исследования и предложенные пороговые значения необходимы для подтверждения в будущих многоцентровых исследованиях, которые могли бы обеспечить более точную дифференциальную диагностику образований надпочечников в клинической практике.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Differential diagnosis of pheochromocytoma from adrenal adenoma is extremely important at the stage of planning surgical intervention. In some cases, laboratory data and computed tomography (CT) are insufficient for making an accurate diagnosis. In our study, we aimed to evaluate the possibilities of magnetic resonance imaging in the diagnosis of adrenal pheochromocytoma.</p></sec><sec><title>Aim</title><p>Aim. Evaluation of the possibilities of using multiparametric magnetic resonance imaging in the differential diagnostic of adrenal pheochromocytoma.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. The study included 69 patients with adrenal gland tumors who underwent surgery due to the clinically malignant potential of the tumor or its hormonal activity. All patients underwent multiparametric magnetic resonance imaging. During the postprocessing, the signal intensity of the adrenal gland tumors, signal intensity indices (including in comparison with the spleen and muscles) were evaluated in various series in order to assess the differences between these indicators in pheochromocytomas and other adrenal gland tumors.</p></sec><sec><title>Results</title><p>Results. Pheochromocytomas are characterized by the following thresholds: signal intensity index on T2-weighted lesion compared to the muscles (T2 index) &gt; 2.630: signal intensity index on dual-echo series (SI index) &lt; 16.600, chemical shift index compared to the spleen (ASR) &gt; 0.840.</p></sec><sec><title>Conclusions</title><p>Conclusions. Each of the studied parameters had a number of exceptions and limitations, therefore, the results of this study and the proposed thresholds are necessary for confirmation in future multicenter studies that could provide a more accurate differential diagnosis of adrenal gland tumors in clinical practice.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>мультипараметрическая магнитно-резонансная томография надпочечников</kwd><kwd>индекс интенсивности сигнала</kwd><kwd>феохромоцитома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>multiparametric magnetic resonance imaging of the adrenal glands</kwd><kwd>signal intensity index</kwd><kwd>pheochromocytoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Glazer D.I., Mayo-Smith W.W. Management of incidental adrenal masses: an update. 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