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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1547</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1547</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕХНОЛОГИИ ЛУЧЕВОЙ ДИАГНОСТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RADIOLOGICAL TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>Применение радиомики в диагностике рака шейки матки: систематический обзор</article-title><trans-title-group xml:lang="en"><trans-title>Application of radiomics in the diagnosis of cervical cancer: systematic review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1641-6452</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солодкий</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Solodky</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Солодкий Владимир Алексеевич – академик РАН, доктор мед. наук, профессор, директор ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0000-0002-1641-6452" ext-link-type="uri">https://orcid.org/0000-0002-1641-6452</ext-link></p></bio><bio xml:lang="en"><p>Vladimir A. Solodkiy – Academician of the Russian Academy of Sciences, Doct. of Sci. (Med.), Professor, Director of the Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation, Moscow<ext-link xlink:href="https://orcid.org/0000-0002-1641-6452" ext-link-type="uri">https://orcid.org/0000-0002-1641-6452</ext-link></p></bio><email xlink:type="simple">mailbox@rncrr.rssi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5994-0468</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нуднов</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nudnov</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нуднов Николай Васильевич – доктор мед. наук, профессор, заместитель директора по научной работе, заведующий научно-исследовательским отделом комплексной диагностики заболеваний и радиотерапии ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России; профессор кафедры рентгенологии и радиологии ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России;</p><p>заместитель директора по научной работе, профессор кафедры онкологии и рентгенорадиологии ФГАОУ ВО “Российский университет дружбы народов имени Патриса Лумумбы” Минобрнауки России, Москва<ext-link xlink:href="https://orcid.org/0000-0001-5994-0468" ext-link-type="uri">https://orcid.org/0000-0001-5994-0468</ext-link>E-mail: mailbox@rncrr.rssi.ru</p></bio><bio xml:lang="en"><p>Nikolay V. Nudnov – Doct. of Sci. (Med.), Professor, Deputy Director for Scientific Work, Head of the Research Department for Complex Diagnostics of Diseases and Radiotherapy, Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation;</p><p>Professor, Department of Roentgenoradiology and Radiology, Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation;</p><p>Professor, Department of Oncology and Radiology, Peoples' Friendship University of Russia named after Patrice Lumumba of the Ministry of Science and Higher Education of the Russian Federation, Moscow<ext-link xlink:href="https://orcid.org/0000-0001-5994-0468" ext-link-type="uri">https://orcid.org/0000-0001-5994-0468</ext-link>E-mail: mailbox@rncrr.rssi.ru</p></bio><email xlink:type="simple">mailbox@rncrr.rssi.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-3006-8210</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Султанова</surname><given-names>П. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sultanova</surname><given-names>P. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Султанова Пери Назимовна – клинический ординатор по специальности “рентгенология” ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России”, Москва<ext-link xlink:href="https://orcid.org/0009-0009-3006-8210" ext-link-type="uri">https://orcid.org/0009-0009-3006-8210</ext-link>E-mail: sulperi14@mail.ru</p></bio><bio xml:lang="en"><p>Peri N. Sultanova – clinical resident in the specialty “Radiology” of the Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation, Moscow<ext-link xlink:href="https://orcid.org/0009-0009-3006-8210" ext-link-type="uri">https://orcid.org/0009-0009-3006-8210</ext-link>E-mail: sulperi14@mail.ru</p><p> </p></bio><email xlink:type="simple">sulperi14@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2552-5754</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксенова</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Aksenova</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аксенова Светлана Павловна – канд. мед. наук, научный сотрудник лаборатории рентгенорадиологии научно-исследовательского отдела комплексной диагностики заболеваний и радиотерапии ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0000-0003-2552-5754" ext-link-type="uri">https://orcid.org/0000-0003-2552-5754</ext-link>E-mail: fabella@mail.ru</p></bio><bio xml:lang="en"><p>Svetlana P. Aksenova – Cand. of Sci. (Med.), research fellow, Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation; Assistant Professor, Department of Oncology and Roentgenology named after V.P. Kharchenko, Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), Moscow<ext-link xlink:href="https://orcid.org/0000-0003-2552-5754" ext-link-type="uri">https://orcid.org/0000-0003-2552-5754</ext-link>E-mail: fabella@mail.ru</p></bio><email xlink:type="simple">fabella@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4036-5883</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борисов Александр Александрович –  аналитик ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0000-0003-4036-5883" ext-link-type="uri">https://orcid.org/0000-0003-4036-5883</ext-link></p></bio><bio xml:lang="en"><p>Aleksandr A. Borisov – analyst, Pirogov Russian National Research Medical University, Moscow<ext-link xlink:href="https://orcid.org/0000-0003-4036-5883" ext-link-type="uri">https://orcid.org/0000-0003-4036-5883</ext-link></p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-7535-8523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шахвалиева</surname><given-names>Э. С.-А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shakhvalieva</surname><given-names>E. S.-A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шахвалиева Элина Саид-Аминовна – врач-рентгенолог ГБУЗ города Москвы “Детская городская клиническая больница № 9 им. Г.Н. Сперанского ДЗ города Москвы”, Москва<ext-link xlink:href="https://orcid.org/0009-0000-7535-8523" ext-link-type="uri">https://orcid.org/0009-0000-7535-8523</ext-link></p></bio><bio xml:lang="en"><p>Elina S.-A. Shakhvalieva – radiologist at the G.N. Speransky Children's City Clinical Hospital No. 9 of Moscow Healthcare Department, Moscow<ext-link xlink:href="https://orcid.org/0009-0000-7535-8523" ext-link-type="uri">https://orcid.org/0009-0000-7535-8523</ext-link></p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0375-1291</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карелидзе</surname><given-names>Д. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Karelidze</surname><given-names>D. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карелидзе Давид Георгиевич – клинический ординатор по специальности “рентгенология” ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0009-0002-0375-1291" ext-link-type="uri">https://orcid.org/0009-0002-0375-1291</ext-link></p></bio><bio xml:lang="en"><p>David G. Karelidze – clinical resident in the specialty “Radiology” of the Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation, Moscow<ext-link xlink:href="https://orcid.org/0009-0002-0375-1291" ext-link-type="uri">https://orcid.org/0009-0002-0375-1291</ext-link></p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-0407-0953</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванников</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivannikov</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванников Михаил Евгеньевич – врач-рентгенолог ГБУЗ города Москвы “Городская клиническая больница имени А.К. Ерамишанцева ДЗ города Москвы”, Москваhttps://orcid.org/0009-0007-0407-0953</p></bio><bio xml:lang="en"><p>Mikhail E. Ivannikov – radiologist at the A.K. Yeramishantsev City Clinical Hospital of Moscow Healthcare Department, Moscow<ext-link xlink:href="https://orcid.org/0009-0007-0407-0953" ext-link-type="uri">https://orcid.org/0009-0007-0407-0953</ext-link></p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маковецкая</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Makovetskaya</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маковецкая Алена Игоревна – клинический ординатор по специальности “рентгенология” ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0009-0007-3964-7708" ext-link-type="uri">https://orcid.org/0009-0007-3964-7708</ext-link></p></bio><bio xml:lang="en"><p>Alena I. Makoveckaya – clinical resident in the specialty “Radiology” of the Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation, Moscow<ext-link xlink:href="https://orcid.org/0009-0007-3964-7708" ext-link-type="uri">https://orcid.org/0009-0007-3964-7708</ext-link></p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8927-2242</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>С. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>S. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенова Софья Романовна – студентка ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Москва<ext-link xlink:href="https://orcid.org/0009-0001-8927-2242" ext-link-type="uri">https://orcid.org/0009-0001-8927-2242</ext-link></p></bio><bio xml:lang="en"><p>Sofya R. Semenova – student, Pirogov Russian National Research Medical University, Moscow<ext-link xlink:href="https://orcid.org/0009-0001-8927-2242" ext-link-type="uri">https://orcid.org/0009-0001-8927-2242</ext-link></p></bio><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России; ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России; ФГАОУ ВО “Российский университет дружбы народов имени Патриса Лумумбы” Минобрнауки России</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation; Peoples' Friendship University of Russia named after Patrice Lumumba</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ “Российский научный центр рентгенорадиологии” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation; Peoples' Friendship University of Russia named after Patrice Lumumba</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ города Москвы “Детская городская клиническая больница № 9 им. Г.Н. Сперанского ДЗ города Москвы”</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>G.N. Speransky Children's City Clinical Hospital No. 9 of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ГБУЗ города Москвы “Городская клиническая больница имени А.К. Ерамишанцева ДЗ города Москвы”</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>A.K. Yeramishantsev City Clinical Hospital of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-7"><institution>ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>09</month><year>2025</year></pub-date><volume>29</volume><issue>3</issue><fpage>91</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Солодкий В.А., Нуднов Н.В., Султанова П.Н., Аксенова С.П., Борисов А.А., Шахвалиева Э.С., Карелидзе Д.Г., Иванников М.Е., Маковецкая А.И., Семенова С.Р., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Солодкий В.А., Нуднов Н.В., Султанова П.Н., Аксенова С.П., Борисов А.А., Шахвалиева Э.С., Карелидзе Д.Г., Иванников М.Е., Маковецкая А.И., Семенова С.Р.</copyright-holder><copyright-holder xml:lang="en">Solodky V.A., Nudnov N.V., Sultanova P.N., Aksenova S.P., Borisov A.A., Shakhvalieva E.S., Karelidze D.G., Ivannikov M.E., Makovetskaya A.I., Semenova S.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1547">https://medvis.rdsmedia.ru/jour/article/view/1547</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: проанализировать результаты изучения эффективности применения радиомического анализа при интерпретации лучевых изображений в уточнении диагностики рака шейки матки.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведен систематический поиск медицинских статей в базах данных PubМed/MEDLINE, eLibrary, Scopus, в ресурсах NCCN, ESUR, ACR.</p></sec><sec><title>Результаты</title><p>Результаты. При подборе медицинских статьей было выявлено в общей сложности 289 уникальных публикации, 218 из которых соответствовали критериям исключения. В итоговый обзор вошла 71 статья. Оценка средних точностных характеристик моделей производилась по значению площади под ROC-кривой (AUC), в том числе точность, чувствительность, специфичность и C-индекс.</p></sec><sec><title>Заключение</title><p>Заключение. Рассмотрены основные ключевые аспекты и достоинства применения радиомики и текстурного анализа изображений при диагностике рака шейки матки. Внедрение радиомического анализа привело к обновленному восприятию анализа медицинских изображений. Результаты ряда исследований демонстрируют, что данные, извлекаемые с помощью радиомического анализа, обладают значительной диагностической и прогностической ценностью, позволяя объективно оценивать характеристики опухоли, ее стадию и распространенность, проводить дифференциальную диагностику новообразований.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: To analyze the results of a study on the effectiveness of radiomic analysis in the interpretation of radiation images in clarifying the diagnosis of cervical cancer.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. A systematic literature search was conducted in the PubMed/MEDLINE, eLibrary, and Scopus databases, as well as in NCCN, ESUR, and ACR resources.</p></sec><sec><title>Results</title><p>Results. When selecting medical articles, a total of 289 unique publications were identified, 218 of which met the exclusion criteria. The final review included 71 articles. The average accuracy characteristics of the models were estimated based on the area under the ROC curve (AUC), including accuracy, sensitivity, specificity, and C-index.</p></sec><sec><title>Conclusion</title><p>Conclusion. The main key aspects and advantages of the use of radiomics and textural image analysis in the diagnosis of cervical cancer are considered. The introduction of radiomic analysis has led to a renewed perception of medical image analysis. The results of a number of studies demonstrate that the data extracted using radiomic analysis have significant diagnostic and prognostic value, allowing an objective assessment of tumor characteristics, its stage and prevalence, and differential diagnosis of neoplasms.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>текстурный анализ</kwd><kwd>рак шейки матки</kwd><kwd>радиомика</kwd><kwd>онкогинекология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>texture analysis</kwd><kwd>cervical cancer</kwd><kwd>radiomics</kwd><kwd>oncogynecology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Всемирная организация здравоохранения, 2023,17 ноября. Рак шейки матки. https://www.who.int/ru/news-room/fact-sheets/detail/cervical-cancer?utm_source=chatgpt.com</mixed-citation><mixed-citation xml:lang="en">World Health Organization, 2023, november 17. Cervical cancer. 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