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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1520</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1520</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДЕТСКАЯ РЕНТГЕНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PEDIATRIC RADIOLOGY</subject></subj-group></article-categories><title-group><article-title>Перфузия и внутриневральное давление седалищного нерва при сахарном диабете 1 типа в молодом возрасте: мультимодальная оценка (УЗИ, МРТ)</article-title><trans-title-group xml:lang="en"><trans-title>Perfusion and intraneural pressure of the sciatic nerve in type 1 diabetes mellitus at a young age: multimodal assessment (ultrasound, MRI)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7517-3393</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фомина Светлана Викторовна – канд. мед. наук, доцент, заведующая отделением, врач ультразвуковой диагностики ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск.</p><p>https://orcid.org/0000-0001-7517-3393</p><p>E-mail: statfom@mail.ru</p></bio><bio xml:lang="en"><p>Svetlana V. Fomina – Cand. of Sci. (Med.), Associate Professor of the Department of Radiation Diagnostics and Radiation Therapy, Head of the Department – Doctor of Ultrasound Diagnostics, Siberian State Medical University, Tomsk.</p><p> https://orcid.org/0000-0001-7517-3393</p><p>E-mail: statfom@mail.ru</p></bio><email xlink:type="simple">statfom@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2667-4842</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самойлова</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Samoilova</surname><given-names>Iu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самойлова Юлия Геннадьевна – доктор мед. наук, профессор, заведующая кафедрой педиатрии с курсом эндокринологии  ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск.</p><p>https://orcid.org/0000-0002-2667-4842</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=samoilova_y@inbox.ru" ext-link-type="uri">samoilova_y@inbox.ru</ext-link></p></bio><bio xml:lang="en"><p>Iuliia G. Samoilova – Doct. of Sci. (Med.), Professor, Head Department of Pediatrics with a course of endocrinology, Siberian State Medical University, Tomsk.</p><p>https://orcid.org/0000-0002-2667-4842</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=samoilova_y@inbox.ru" ext-link-type="uri">samoilova_y@inbox.ru</ext-link></p></bio><email xlink:type="simple">samoilova_y@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0589-0260</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тонких</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tonkikh</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тонких Ольга Сергеевна – канд. мед. наук, заведующая отделением томографических методов ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск.</p><p>https://orcid.org/0000-0003-0589-0260</p><p>E-mail: ostonkih@mail.ru</p></bio><bio xml:lang="en"><p>Olga S. Tonkikh – Cand. of Sci. (Med.),  Chair of the Department of Tomographic Methods, Siberian State Medical University, Tomskhttps://orcid.org/0000-0003-0589-0260</p><p>E-mail: ostonkih@mail.ru</p></bio><email xlink:type="simple">ostonkih@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8142-1226</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кошмелева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Koshmeleva</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кошмелева Марина Владиславовна – канд. мед. наук, доцент, доцент кафедры педиатрии с курсом эндокринологии ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск.</p><p>https://orcid.org/0000-0001-8142-1226</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=mvbulavko@mail.ru" ext-link-type="uri">mvbulavko@mail.ru</ext-link></p></bio><bio xml:lang="en"><p>Marina V. Koshmeleva – Cand. of Sci. (Med.), Associate Professor of the Department of Pediatrics with a Course of Endocrinology, Siberian State Medical University, Tomsk</p><p>https://orcid.org/0000-0001-8142-1226</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=mvbulavko@mail.ru" ext-link-type="uri">mvbulavko@mail.ru</ext-link></p></bio><email xlink:type="simple">mvbulavko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6519-8906</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Качанов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kachanov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Качанов Дмитрий Андреевич – лаборант-исследователь кафедры педиатрии с курсом эндокринологии ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск.</p><p>https://orcid.org/0000-0002-6519-8906</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=doctorssmupf@gmail.com" ext-link-type="uri">doctorssmupf@gmail.com</ext-link></p></bio><bio xml:lang="en"><p>Dmitriy A. Kachanov – Laboratory researcher at the Department of Pediatrics with a course of endocrinology, Siberian State Medical University, Tomsk.</p><p>https://orcid.org/0000-0002-6519-8906</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=doctorssmupf@gmail.com" ext-link-type="uri">doctorssmupf@gmail.com</ext-link></p></bio><email xlink:type="simple">doctorssmupf@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2825-5035</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трифонова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Trifonova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трифонова Екатерина Ивановна – ассистент кафедры педиатрии с курсом эндокринологии ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск.</p><p>https://orcid.org/0000-0002-2825-5035</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=trifonowa.18@yandex.ru" ext-link-type="uri">trifonowa.18@yandex.ru</ext-link></p></bio><bio xml:lang="en"><p>Ekaterina I. Trifonova – Assistant of the department of pediatrics with a course of endocrinology, Siberian State Medical University, Tomsk</p><p>https://orcid.org/0000-0002-2825-5035</p><p>E-mail: <ext-link xlink:href="https://e.mail.ru/compose?To=trifonowa.18@yandex.ru" ext-link-type="uri">trifonowa.18@yandex.ru</ext-link></p></bio><email xlink:type="simple">trifonowa.18@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0025-2147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зоркальцев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zorkaltsev</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зоркальцев Максим Александрович – доктор мед. наук, доцент кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России, Томск<ext-link xlink:href="https://orcid.org/0000-0003-0025-2147" ext-link-type="uri">https://orcid.org/0000-0003-0025-2147</ext-link>E-mail: Zorkaltsev@mail.ru</p></bio><bio xml:lang="en"><p>Maxim A. Zorkaltsev – MD, Doct. of Sci. (Med.), Associate Professor of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk<ext-link xlink:href="https://orcid.org/0000-0003-0025-2147" ext-link-type="uri">https://orcid.org/0000-0003-0025-2147</ext-link>E-mail: Zorkaltsev@mail.ru</p></bio><email xlink:type="simple">zorkaltsev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>04</month><year>2025</year></pub-date><volume>29</volume><issue>2</issue><fpage>98</fpage><lpage>107</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фомина С.В., Самойлова Ю.Г., Тонких О.С., Кошмелева М.В., Качанов Д.А., Трифонова Е.И., Зоркальцев М.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Фомина С.В., Самойлова Ю.Г., Тонких О.С., Кошмелева М.В., Качанов Д.А., Трифонова Е.И., Зоркальцев М.А.</copyright-holder><copyright-holder xml:lang="en">Fomina S.V., Samoilova I.G., Tonkikh O.S., Koshmeleva M.V., Kachanov D.A., Trifonova E.I., Zorkaltsev M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1520">https://medvis.rdsmedia.ru/jour/article/view/1520</self-uri><abstract><p>Диабетическая полинейропатия относится к часто встречаемым осложнениям сахарного диабета. Характеризуется поражением периферических нервов с изменениями перфузии и внутриневрального давления. Поиск новых диагностических инструментов является актуальной задачей.</p><sec><title>Цель исследования</title><p>Цель исследования: оценка перфузии и внутриневрального давления седалищных нервов у подростков с сахарным диабетом 1 типа с использованием мультимодального подхода (УЗИ, МРТ).</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Пациенты с сахарным диабетом 1 типа в возрасте 13–17 лет (n = 50). Всем пациентам дважды в динамике было выполнено ультразвуковое исследование периферических нервов нижних конечностей с использованием серошкального режима, допплерографии, эластографии сдвиговой волной. МРТ седалищного нерва проведено пациентам (n = 20) с использованием методов диффузионно-тензорной трактографии и перфузионного метода один раз.</p></sec><sec><title>Выводы</title><p>Выводы. Мультимодальный подход (УЗИ, МРТ) позволяет охарактеризовать перфузию и внутриневральное давление седалищных нервов у подростков с сахарным диабетом 1 типа. Усиление МР-перфузии седалищных нервов сопровождается повышением ультразвуковой жесткости, коэффициента ультразвуковой оценки периферических нервов у подростков с сахарным диабетом 1 типа.</p></sec></abstract><trans-abstract xml:lang="en"><p>Diabetic polyneuropathy (DPN) is a common complication of diabetes mellitus. It is characterized by damage to peripheral nerves with changes in perfusion and intraneural pressure. The search for new diagnostic tools is an urgent task.</p><p>The aim of the study is to assess perfusion and intraneural pressure of the sciatic nerves in adolescents with type 1 diabetes mellitus using a multimodal approach (ultrasound, MRI).</p><sec><title>Materials and methods</title><p>Materials and methods. Patients with type 1 diabetes mellitus aged 13–17 years (n = 50). All patients underwent ultrasound examination of the peripheral nerves of the lower extremities twice dynamically, using a greyscale mode, Dopplerography, and shear wave elastography. MRI of the sciatic nerve was performed in patients (n = 20) using diffusion tensor tractography and perfusion methods once.</p></sec><sec><title>Conclusions</title><p>Conclusions. A multimodal approach (ultrasound, MRI) allows us to characterize sciatic nerve perfusion and intraneural pressure in adolescents with type 1 diabetes mellitus. Increased MR perfusion of the sciatic nerves is accompanied by an increase in ultrasonic stiffness and the coefficient of ultrasound assessment of peripheral nerves in adolescents with type 1 diabetes mellitus.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>диабетическая полинейропатия</kwd><kwd>ультразвуковые исследование нервов</kwd><kwd>площадь поперечного сечения</kwd><kwd>эластография</kwd><kwd>магнитно-резонансная томография</kwd><kwd>перфузия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetic polyneuropathy</kwd><kwd>ultrasound examination of nerves</kwd><kwd>cross-sectional area</kwd><kwd>elastography</kwd><kwd>magnetic resonance imaging</kwd><kwd>perfusion</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы заявляют об отсутствии финансирования</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kallinikou D., Soldatou A., Tsentidis C. et al. 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