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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1496</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1496</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГРУДНАЯ КЛЕТКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THORAX</subject></subj-group></article-categories><title-group><article-title>Полисерозит как негативный прогностический фактор COVID-19. Наблюдения ГКБ №52 в начале и в конце пандемии</article-title><trans-title-group xml:lang="en"><trans-title>Patients monitoring in the City Clinical Hospital No. 52 at the beginning and end of the pandemic</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7858-7820</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сукмарова</surname><given-names>З. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukmarova</surname><given-names>Z. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сукмарова Зульфия Наилевна – канд. мед. наук, научный сотрудник ФГБНУ “НИИ ревматологии им. В.А. Насоновой”, Москваhttps://orcid.org/0000-0002-7858-7820</p></bio><bio xml:lang="en"><p>Zulfiya N. Sukmarova – Cand. of Sci. (Med.), research fellow, V.A. Nasonova Research Institute of Rheumatology, Moscowhttps://orcid.org/0000-0002-7858-7820</p></bio><email xlink:type="simple">Suzulfia@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3783-3412</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паршин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishimorov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Паршин Василий Владимирович – доктор мед. наук, заведующий рентгеновским отделением ГБУЗ города Москвы “Городская клиническая больница № 52 ДЗ города Москвы”, Москваhttps://orcid.org/0000-0003-3783-3412</p></bio><bio xml:lang="en"><p>Alexey A. Shishimorov – Radiologist of radiology department, City Clinical Hospital No52 of Moscow Healthcare Department, Moscowhttps://orcid.org/0009-0004-5466-6948</p></bio><email xlink:type="simple">vasilii_parshin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-5466-6948</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишиморов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Parshin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шишиморов Алексей Андреевич – врач рентгенолог ГБУЗ города Москвы “Городская клиническая больница № 52 ДЗ города Москвы”, Москваhttps://orcid.org/0009-0004-5466-6948</p></bio><bio xml:lang="en"><p>Vasily V. Parshin – Radiologist, Head of radiology department, City Clinical Hospital No52 of Moscow Healthcare Department, Moscowhttps://orcid.org/0000-0003-3783-3412</p></bio><email xlink:type="simple">dr.shishimorov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9014-9022</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Громов Александр Игоревич – доктор мед. наук, профессор кафедры лучевой диагностики ФГБОУ ВО “Российский университет медицины” Минздрава России, Москваhttps://orcid.org/0000-0002-9014-9022</p></bio><bio xml:lang="en"><p>Alexander I. Gromov – Doct. of Sci. (Med.), Professor of the Department of Radiation Diagnostics, Russian University of Medicine of the Ministry of Healthcare of the Russian Federation, Moscowhttps://orcid.org/0000-0002-9014-9022</p></bio><email xlink:type="simple">gai8@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ “НИИ ревматологии им. В.А. Насоновой”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ города Москвы “Городская клиническая больница № 52 ДЗ города Москвы”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No52 of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО “Российский университет медицины” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Medicine of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>04</month><year>2025</year></pub-date><volume>29</volume><issue>2</issue><fpage>20</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сукмарова З.Н., Паршин В.В., Шишиморов А.А., Громов А.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сукмарова З.Н., Паршин В.В., Шишиморов А.А., Громов А.И.</copyright-holder><copyright-holder xml:lang="en">Sukmarova Z.N., Shishimorov A.A., Parshin V.V., Gromov A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1496">https://medvis.rdsmedia.ru/jour/article/view/1496</self-uri><abstract><p>Инфекция SARS-CoV-2 продолжает циркулировать среди населения и играть роль иммунологического триггера. Полисерозит, описанный как маркер иммуновоспалительных заболеваний, сегодня привлекает внимание у пациентов, перенесших COVID-19, даже вне контекста респираторной инфекции.</p><sec><title>Цель исслдования</title><p>Цель исслдования: изучение встречаемости выпота в полость перикарда и плевры по данным КТ легких у пациентов с острой пневмонией COVID-19 умеренной и тяжелой степени и сопоставление находок с показателями смертности.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Ретроспективно проанализирована встречаемость экссудации &gt;5 мм по данным КТ грудной клетки, выполненной при поступлении в ковидный стационар, пациентов c острой пневмонией из базы данных периода с 01.02–30.04.2020 и 2022 гг. Критерии невключения: наличие предшествовавшего перикардита или плеврита, гидроперикарда, гидроторакса, ХСН с ФК по NYHA ≥ III, иммуновоспалительного заболевания.</p></sec><sec><title>Результаты</title><p>Результаты. За 3 изучаемых месяца 2020 и 2022 гг. было включено 390 случаев, из которых 58 закончились летальным исходом. Видимый при КТ легких выпот в полость плевры в группе выживших регистрировался у 15%, в группе умерших – у 50% пациентов (OR 3,9; 95%CI 2,5–6,2), выпот в перикардиальную полость – 12 и 57% соответственно (OR 5,6; 95%CI 3,6–8,9). Максимальная толщина выпота также была вдвое больше во второй группе: 13 vs 29 мм в полости плевры, 6 vs 11 мм в полости перикарда. При сравнении частоты встречаемости вовлечения серозных оболочек по годам в 2020 г. выпот в плевральную полость регистрировался у 16%, в 2022 г. –у 22%, в перикардиальную полость в 2020 г. – у 14%, в 2022 г. – у 20% соответственно. При этом группы оказались сопоставимы по возрасту: Ме 59 [95%CI: 49 до 86] лет в 2020 г. и 60 [95%CI: 49 до 87] лет в 2022 г. (р = 0,6), а также по тяжести пневмонии по КТ: 1,65 ± 0,2 vs 1,55 ± 0,2 (р = 0,2) соответственно.</p></sec><sec><title>Заключение</title><p>Заключение. 1/5 стационарных пациентов с COVID-19- пневмонией имеют небольшой выпот в серозные полости грудной клетки. Наличие экссудации в плевральную или перикардиальную полость ассоциируется с 4- и 6-кратным увеличением риска смерти таких пациентов. Встречаемость выпота в серозные полости &gt; 5 мм увеличилась в 1,5 раза за 3 года, что может свидетельствовать о сенсибилизации населения.</p></sec></abstract><trans-abstract xml:lang="en"><p>SARS-CoV-2 infection continues to circulate in the population and to play a role of immunological trigger. Polyserositis, described as a marker of immunoinflammatory diseases, today can often be found in patients who have had COVID-19, even irrespective of respiratory infection.</p><sec><title>Objective</title><p>Objective: to study the incidence of pericardial and pleural effusion based on lung CT scans in patients with moderate to severe acute COVID-19 pneumonia and to compare findings with mortality rates.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The incidence of exudation &gt;5 mm according to data from a chest CT scan performed upon admission to a Covid hospital in patients with acute pneumonia from the database for the period from February 1 to April 30, 2020 and 2022. Criteria non-inclusion: presence of previous pericarditis or pleurisy, hydropericardium, hydrothorax, CHF with NYHA class ≥3, immunoinflammatory disease.</p></sec><sec><title>Results</title><p>Results. Over the 3 months studied in 2020 and 2022, 390 cases were included, of which 58 ended in death. Pleural effusion visible on CT of the lungs in the group of survivors were recorded in 15%, in the group of deceased – in 50% of patients (OR 3.9; 95%CI 2.5–6.2), pericardial effusion – 12 and 57%, respectively (OR 5.6; 95%CI 3.6–8.9). The maximum thickness of the effusion was also twice as large in the second group: 13 vs 29 mm in the cavity pleura, 6 vs 11 mm in the pericardial cavity. When comparing the frequency of serous membranes involvement by year, in 2020 effusion into the pleural cavity was recorded in 16%, in 2022 – in 22%, in the pericardial cavity in 2020 – in 14%, in 2022 – in 20% respectively. At the same time the groups were comparable in age Me 59 [95%CI: 49 to 86] years in 2020 and 60 [95%CI: 49 to 87] years in 2022 (p = 0.6), as well as by the severity of pneumonia according to CT 1.65 ± 0.2 vs 1.55 ± 0.2 (p = 0.2) respectively.</p></sec><sec><title>Conclusions</title><p>Conclusions. 1/5 of inpatients with COVID-19 pneumonia have a small effusion in the serous cavities of the chest. The exudation into the pleural or pericardial cavities are associated with a 4- and 6-fold increased risk of death in these patients. The incidence of serous effusion &gt;5 mm increased 1.5 times over 3 years, which may indicate patient sensitization.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>полисерозит как прогностический фактор исхода COVID-19</kwd><kwd>плевральный выпот</kwd><kwd>перикардиальный выпот</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>polyserositis as a prognostic factor for COVID-19 outcome</kwd><kwd>pleural effusion</kwd><kwd>pericardial effusion</kwd><kwd>computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Babar M., Jamil H., Mehta N. et al. Short- and Long-Term Chest-CT Findings after Recovery from COVID-19: A Systematic Review and Meta-Analysis. Diagnostics. 2024; 14 (6): 621. http://doi.org/10.3390/diagnostics14060621</mixed-citation><mixed-citation xml:lang="en">Babar M., Jamil H., Mehta N. et al. Short- and Long-Term Chest-CT Findings after Recovery from COVID-19: A Systematic Review and Meta-Analysis. Diagnostics. 2024; 14 (6): 621. http://doi.org/10.3390/diagnostics14060621</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Stoian M., Procopiescu B., Şeitan S., Scarlat G. Post-COVID-19 syndrome: Insights into a novel post-infectious systemic disorder. J. Med. Life. 2023; 16 (2): 195–202. http://doi.org/10.25122/jml-2022-0329</mixed-citation><mixed-citation xml:lang="en">Stoian M., Procopiescu B., Şeitan S., Scarlat G. Post-COVID-19 syndrome: Insights into a novel post-infectious systemic disorder. J. Med. Life. 2023; 16 (2): 195–202. http://doi.org/10.25122/jml-2022-0329</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Сукмарова З.Н., Ибрагимова Ф.М., Баев А.А., Осипова Н.Ю., Громов А.И. Выпот в полость плевры и перикарда, случайно выявленный при магнитно-резонансной томографии молочных желез у пациенток, перенесших COVID-19: ретроспективное исследование случай-контроль. Лучевая диагностика и терапия. 2022; 14 (1): 54–65. http://doi.org/10.22328/2079-5343-2023-14-1-54-65</mixed-citation><mixed-citation xml:lang="en">Sukmarova Z.N., Ibragimova F.M., Baev A.A. et al. Pleural and pericardial effusion incidentally detected on breast magnetic resonance imaging in post-COVID-19 patients: retrospective case-control study. Diagnostic radiology and radiotherapy. 2023; 14 (1): 37–48. http://doi.org/10.22328/2079-5343-2023-14-1-54-65 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Dini F.L., Baldini U., Bytyçi I. et al. Acute pericarditis as a major clinical manifestation of long COVID-19 syndrome. Int. J. Cardiol. 2023; 374: 129–134. http://doi.org/10.1016/j.ijcard.2022.12.019</mixed-citation><mixed-citation xml:lang="en">Dini F.L., Baldini U., Bytyçi I. et al. Acute pericarditis as a major clinical manifestation of long COVID-19 syndrome. Int. J. Cardiol. 2023; 374: 129–134. http://doi.org/10.1016/j.ijcard.2022.12.019</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Li P., Shi A., Lu X. et al. Incidence and impact of acute pericarditis in hospitalized COVID-19 patients. J. Am. Heart. Assoc. 2023; 12: e028970. http://doi.org/10.1161/JAHA.122.028970</mixed-citation><mixed-citation xml:lang="en">Li P., Shi A., Lu X. et al. Incidence and impact of acute pericarditis in hospitalized COVID-19 patients. J. Am. Heart. Assoc. 2023; 12: e028970. http://doi.org/10.1161/JAHA.122.028970</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Watanabe A., So M., Iwagami M. et al. One-year follow-up CT findings in COVID-19 patients: A systematic review and meta-analysis. Respirology. 2022; 27: 605–616. http://doi.org/10.1111/resp.14311</mixed-citation><mixed-citation xml:lang="en">Watanabe A., So M., Iwagami M. et al. One-year follow-up CT findings in COVID-19 patients: A systematic review and meta-analysis. Respirology. 2022; 27: 605–616. http://doi.org/10.1111/resp.14311</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Сукмарова З.Н., Ибрагимова Ф.М., Ларина О.М., Громов А.И., Насонов Е.Л. Плеврит и перикардит как причина атипичной боли в грудной клетке у пациентов в раннем периоде после COVID-19. Медицинская визуализация. 2022; 26 (4): 11–22. http://doi.org/10.24835/1607-0763-1232</mixed-citation><mixed-citation xml:lang="en">Sukmarova Z.N., Ibragimova F.M., Larina O.M. et al.Pleurisy and pericarditis as a cause of atypical chest pain in patients with in early post-COVID-19 period. Medical Visualization. 2022; 26 (4): 11–22. http://doi.org/10.24835/1607-0763-1232 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ottaviani S., Franc M., Ebstein E. et al. Lung ultrasonography in patients with COVID-19: comparison with CT. Clin. Radiol. 2020; 75: 877.e1-6. http://doi.org/10.1016/j.crad.2020.07.024</mixed-citation><mixed-citation xml:lang="en">Ottaviani S., Franc M., Ebstein E. et al. Lung ultrasonography in patients with COVID-19: comparison with CT. Clin. Radiol. 2020; 75: 877.e1-6. http://doi.org/10.1016/j.crad.2020.07.024</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Tarbsheh A.H., Leamon A., Chong W.H. et al. Pericardial effusion in COVID-19 patients. Am. J. Med. Sci. 2022; 364 (1): 129–130. http://doi.org/10.1016/j.amjms.2022.01.024</mixed-citation><mixed-citation xml:lang="en">Al-Tarbsheh A.H., Leamon A., Chong W.H. et al. Pericardial effusion in COVID-19 patients. Am. J. Med. Sci. 2022; 364 (1): 129–130. http://doi.org/10.1016/j.amjms.2022.01.024</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bucher A.M., Henzel K., Meyer H.J. et al. Pericardial Effusion Predicts Clinical Outcomes in Patients with COVID-19: A Nationwide Multicenter Study. Acad. Radiol. 2024; 31 (5): 1784–1791. http://doi.org/10.1016/j.acra.2023.12.003</mixed-citation><mixed-citation xml:lang="en">Bucher A.M., Henzel K., Meyer H.J. et al. Pericardial Effusion Predicts Clinical Outcomes in Patients with COVID-19: A Nationwide Multicenter Study. Acad. Radiol. 2024; 31 (5): 1784–1791. http://doi.org/10.1016/j.acra.2023.12.003</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Saraç İ., Aydın S.Ş., Özmen M. et al. Prevalence, Risk Factors, Prognosis, and Management of Pericardial Effusion in COVID-19. J. Cardiovasc. Dev. Dis. 2023; 10 (9): 368. http://doi.org/10.3390/jcdd10090368</mixed-citation><mixed-citation xml:lang="en">Saraç İ., Aydın S.Ş., Özmen M. et al. Prevalence, Risk Factors, Prognosis, and Management of Pericardial Effusion in COVID-19. J. Cardiovasc. Dev. Dis. 2023; 10 (9): 368. http://doi.org/10.3390/jcdd10090368</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Chong W.H., Saha B.K., Conuel E., Chopra A. The incidence of pleural effusion in COVID-19 pneumonia: State-of-the-art review. Heart Lung. 2021; 50 (4): 481–490. http://doi.org/10.1016/j.hrtlng.2021.02.015</mixed-citation><mixed-citation xml:lang="en">Chong W.H., Saha B.K., Conuel E., Chopra A. The incidence of pleural effusion in COVID-19 pneumonia: State-of-the-art review. Heart Lung. 2021; 50 (4): 481–490. http://doi.org/10.1016/j.hrtlng.2021.02.015</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Saha B.K., Chong W.H., Austin A. et al. Pleural abnormalities in COVID-19: a narrative review. J. Thorac. Dis. 2021; 13 (7): 4484–4499. http://doi.org/10.21037/jtd-21-542</mixed-citation><mixed-citation xml:lang="en">Saha B.K., Chong W.H., Austin A. et al. Pleural abnormalities in COVID-19: a narrative review. J. Thorac. Dis. 2021; 13 (7): 4484–4499. http://doi.org/10.21037/jtd-21-542</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Паршин В.В., Бережная Э.Э., Кецкало М.В., Лежнев Д.А. Компьютерно-томографическая семиотика, объем поражения легких и морфологические сопоставления у больных пневмонией (COVID-19) тяжелой и крайне тяжелой степени. Радиология–практика. 2021; 1: 34–51.</mixed-citation><mixed-citation xml:lang="en">Parshin V.V., Berezhnaia E.E., Ketskalo M.V., Lezhnev D.A. The Computer-Tomographic Semiotics, Volume of Lung Damage and Morphological Comparisons in Patients with Severe and Extremely Severe Coronavirus Pneumonia (COVID-19). Radiology-Practice. 2021; 1: 34–51. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Blumfield E., Levin T.L., Kurian J. et al. Imaging Findings in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19). Am. J. Roentgenol. 2021; 216: 507–517. http://doi.org/10.2214/AJR.20.24032</mixed-citation><mixed-citation xml:lang="en">Blumfield E., Levin T.L., Kurian J. et al. Imaging Findings in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19). Am. J. Roentgenol. 2021; 216: 507–517. http://doi.org/10.2214/AJR.20.24032</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Ducloyer M., Gaborit B., Toquet C. et al. Complete post-mortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations. Int. J. Legal. Med. 2020; 134: 2209–2214. http://doi.org/10.1007/s00414-020-02390-1</mixed-citation><mixed-citation xml:lang="en">Ducloyer M., Gaborit B., Toquet C. et al. Complete post-mortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations. Int. J. Legal. Med. 2020; 134: 2209–2214. http://doi.org/10.1007/s00414-020-02390-1</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Zhu Z., Lian X., Su X. et al. From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses. Respir. Res. 2020; 21 (1): 224. http://doi.org/10.1186/s12931-020-01479-w</mixed-citation><mixed-citation xml:lang="en">Zhu Z., Lian X., Su X. et al. From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses. Respir. Res. 2020; 21 (1): 224. http://doi.org/10.1186/s12931-020-01479-w</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Das K.M., Lee E.Y., Enani M.A. et al. CT correlation with outcomes in 15 patients with acute Middle East respiratory syndrome coronavirus. Am. J. Roentgenol. 2015; 204 (4): 736–742. http://doi.org/10.2214/AJR.14.13671</mixed-citation><mixed-citation xml:lang="en">Das K.M., Lee E.Y., Enani M.A. et al. CT correlation with outcomes in 15 patients with acute Middle East respiratory syndrome coronavirus. Am. J. Roentgenol. 2015; 204 (4): 736–742. http://doi.org/10.2214/AJR.14.13671</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
