<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1452</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1452</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕХНОЛОГИИ ЛУЧЕВОЙ ДИАГНОСТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RADIOLOGICAL TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>Влияние современных технологий компьютерной и магнитно-резонансной томографии на дооперационное стадирование рака поджелудочной железы</article-title><trans-title-group xml:lang="en"><trans-title>The influence of modern computer and magnetic resonance imaging technologies on the preoperative staging of pancreatic cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8117-6670</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жарикова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zharikova</surname><given-names>Alexandra V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жарикова Александра Витальевна – врач-ординатор отдела лучевых методов диагностики и лечения ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России, Москва. </p></bio><bio xml:lang="en"><p>Alexandra V. Zharikova – Resident Physician of radiology department, A.V. Vishnevsky National Medical Research Centre of Surgery, Moscow</p></bio><email xlink:type="simple">zha-vit@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7070-3391</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кондратьев</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kondratyev</surname><given-names>Evgeny V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кондратьев Евгений Валерьевич – канд. мед. наук, старший научный сотрудник отдела лучевых методов диагностики и лечения ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России, Москва</p></bio><bio xml:lang="en"><p>Evgeny V. Kondratyev – Cand. of Sсi. (Med.), senior researcher of radiology department, A.V. Vishnevsky National Medical Research Centre of Surgery, Moscow</p></bio><email xlink:type="simple">evgenykondratiev@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9782-7335</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихонова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikhonova</surname><given-names>Valeriya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тихонова Валерия Сергеевна – канд. мед. наук, врач-рентгенолог ФГАУ ВО Первый МГМУ имени И.М. Сеченова Минздрава России (Сеченовский Университет), Москва</p></bio><bio xml:lang="en"><p>Valeriya S. Tikhonova – Cand. of Sсi. (Med.), radiologist of the First Moscow State Medical University named after I.M. Sechenov, Moscow</p></bio><email xlink:type="simple">vdovenkobc28@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0781-9898</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Груздев</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Gruzdev</surname><given-names>Ivan S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Груздев Иван Сергеевич – канд. мед. наук, научный сотрудник отдела лучевых методов диагностики и лечения  ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России, Москва</p></bio><bio xml:lang="en"><p>Ivan S. Gruzdev – Cand. of Sсi. (Med.), researcher of radiology department, A.V. Vishnevsky National Medical Research Centre of Surgery, Moscow</p></bio><email xlink:type="simple">gruzdev_van@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5032-4164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ростовцев</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rostovtsev</surname><given-names>Mikhail V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ростовцев Михаил Владиславович – доктор мед. наук, старший научный сотрудник отделения лучевых методов диагностики ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России; профессор кафедры рентгенологии и радиологии ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России; заведующий рентгенологическим отделением ГБУЗ “Городская клиническая больница имени М.Е. Жадкевича ДЗ города Москвы” Москва</p></bio><bio xml:lang="en"><p>Mikhail V. Rostovtsev – Doct. of Sci. (Med.), Senior Researcher, Department of Radiation Diagnostic Methods, A.V. Vishnevsky National Medical Research Center of Surgery; Professor of the Department of Radiology and Roentgenology, Russian Medical Academy of Continuing Professional Education; Head of the Radiology Department, M.E. Zhadkevich City Clinical hospital, Moscow</p></bio><email xlink:type="simple">rostovtsevmv@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9074-5676</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марков</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Markov</surname><given-names>Pavel V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марков Павел Викторович – доктор мед. наук, заведующий отделением абдоминальной хирургии ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России, Москва</p></bio><bio xml:lang="en"><p>Pavel V. Markov – Doct. of Sci. (Med.), Head of the Abdominal Surgery Department, A.V. Vishnevsky National Medical Research Center of Surgery, Moscow</p></bio><email xlink:type="simple">pvmarkov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1555-1596</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стручков</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Struchkov</surname><given-names>Vladimir Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Стручков Владимир Юрьевич – канд. мед. наук, младший научный сотрудник отделения абдоминальной хирургии ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России, Москва</p></bio><bio xml:lang="en"><p>Vladimir Yu. Struchkov – PhD, junior researcher, Abdominal Surgery Department, A.V. Vishnevsky National Medical Research Center of Surgery, Moscow</p></bio><email xlink:type="simple">doc.struchkov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9357-0998</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кармазановский</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Karmazanovsky</surname><given-names>Grigory G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кармазановский Григорий Григорьевич – академик РАН, доктор мед. наук, профессор, заведующий отделом лучевых методов диагностики и лечения ФГБУ “НМИЦ хирургии им. А.В. Вишневского” Минздрава России;профессор кафедры лучевой диагностики и терапии медико-­биологического факультета ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Москва. </p></bio><bio xml:lang="en"><p>Grigory G. Karmazanovsky – Russian Academy of Sciences (RAS) Full Member, Doct. of Sci. (Med.), Professor, Heаd of the Diagnostic Rаdiology Depаrtment at the А.V. Vishnevsky Nаtionаl Mediсаl Reseаrсh Сenter of Surgery; Professor of radiology department, Pirogov Russian national research medical university, Moscow</p></bio><email xlink:type="simple">karmazanovsky@ixv.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ “Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАУ ВО Первый МГМУ имени И.М. Сеченова Минздрава России (Сеченовский Университет), Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ “Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского” Минздрава России&#13;
ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России;&#13;
ГБУЗ города Москвы “Городская клиническая больница имени М.Е. Жадкевича (ГКБ № 71) ДЗ города Москвы”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Healthcare of the Russian Federation;&#13;
M.E. Zhadkevich City Clinical Hospital (City Hospital No71);&#13;
Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБУ “Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского” Минздрава России;&#13;
&#13;
ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Москва.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.V. Vishnevsky National Medical Research Center of Surgery of the Ministry of Healthcare of the Russian Federation;&#13;
Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2024</year></pub-date><volume>28</volume><issue>2</issue><fpage>118</fpage><lpage>133</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жарикова А.В., Кондратьев Е.В., Тихонова В.С., Груздев И.С., Ростовцев М.В., Марков П.В., Стручков В.Ю., Кармазановский Г.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Жарикова А.В., Кондратьев Е.В., Тихонова В.С., Груздев И.С., Ростовцев М.В., Марков П.В., Стручков В.Ю., Кармазановский Г.Г.</copyright-holder><copyright-holder xml:lang="en">Zharikova A.V., Kondratyev E.V., Tikhonova V.S., Gruzdev I.S., Rostovtsev M.V., Markov P.V., Struchkov V.Y., Karmazanovsky G.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1452">https://medvis.rdsmedia.ru/jour/article/view/1452</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: обзор и анализ зарубежной и отечественной литературы, клинических рекомендаций, посвященных оценке распространенности опухоли протоковой аденокарциномы поджелудочной железы и тактике лечения пациентов с выявленным новообразованием поджелудочной железы.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведен анализ отечественных и зарубежных источников литературы по базам PubMed с использованием ключевых слов “pancreatic cancer”, “vascular invasion”, “locally advanced cancer”, “cancer statistics”, “CT”, “MRI”, “neoadjuvant therapy” за последние 5–10 лет.</p><p>В данном обзоре рассмотрены основные методы визуализации, используемые для определения взаимоотношения опухоли с прилежащими магистральными сосудами и оценки резектабельности рака поджелудочной железы.</p></sec><sec><title>Заключение</title><p>Заключение. Компьютерная томография и магнитно-резонансная томография с контрастным усилением – первоочередные методы диагностики протоковой аденокарциномы поджелудочной железы. Они высокоинформативны для оценки контакта/вовлечения сосудистых структур, распространенности опухолевого процесса, однако стандартные критерии неинформативны для оценки ответа на химиотерапевтическое лечение, поэтому требуется внедрение альтернативных способов его оценки, одним из которых является радиомика, лежащая в основе работы искусственного интеллекта и программ глубокого машинного обучения.</p></sec></abstract><kwd-group xml:lang="ru"><kwd>протоковая аденокарцинома поджелудочной железы</kwd><kwd>вовлечение сосудов</kwd><kwd>местнораспространенная опухоль</kwd><kwd>неоадъювантная химиотерапия</kwd><kwd>КТ</kwd><kwd>МРТ</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ACS Journals, Cancer statistics 2020, http://doi.org/10.3322/caac.21590</mixed-citation><mixed-citation xml:lang="en">ACS Journals, Cancer statistics 2020, http://doi.org/10.3322/caac.21590</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2020 году (заболеваемость и смертность) / Под ред. А.Д. Каприна, В.В. Старинского, А.О. Шахзадовой. 2021.</mixed-citation><mixed-citation xml:lang="en">Malignant neoplasms in Russia in 2020 (morbidity and mortality) / Eds A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova. 2021. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Park W., Chawla A., O’Reilly E.M. Pancreatic Cancer: A Review. JAMA. 2021; 326 (9): 851–862. https://doi.org/10.1001/jama.2021.13027</mixed-citation><mixed-citation xml:lang="en">Park W., Chawla A., O’Reilly E.M. Pancreatic Cancer: A Review. JAMA. 2021; 326 (9): 851–862. https://doi.org/10.1001/jama.2021.13027</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Buchs N.C., Chilcott M., Poletti P.-A. et al. Vascular invasion in pancreatic cancer: Imaging modalities, preoperative diagnosis and surgical management. Wld J. Gastroenterol. 2010; 16 (7): 818–831. https://doi.org/10.3748/wjg.v16.i7.818</mixed-citation><mixed-citation xml:lang="en">Buchs N.C., Chilcott M., Poletti P.-A. et al. Vascular invasion in pancreatic cancer: Imaging modalities, preoperative diagnosis and surgical management. Wld J. Gastroenterol. 2010; 16 (7): 818–831. https://doi.org/10.3748/wjg.v16.i7.818</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Hawary M.M., Francis I.R., Chari S.T. et al. Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the Society of Abdominal Radiology and the American Pancreatic Association. Radiology. 2014; 270 (1): 248–260. https://doi.org/10.1148/radiol.13131184</mixed-citation><mixed-citation xml:lang="en">Al-Hawary M.M., Francis I.R., Chari S.T. et al. Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the Society of Abdominal Radiology and the American Pancreatic Association. Radiology. 2014; 270 (1): 248–260. https://doi.org/10.1148/radiol.13131184</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации Министерства здравоохранения РФ “Рак поджелудочной железы, 2021 год” https://cr.minzdrav.gov.ru/schema/355_4</mixed-citation><mixed-citation xml:lang="en">Clinical recommendations of the Ministry of Health of the Russian Federation, pancreatic cancer, 2021” https://cr.minzdrav.gov.ru/schema/355_4 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gugenheim J., Crovetto A., Petrucciani N. Neoadjuvant therapy for pancreatic cancer. Updates Surg. 2022; 74 (1): 35–42. https://doi.org/10.1007/s13304-021-01186-1</mixed-citation><mixed-citation xml:lang="en">Gugenheim J., Crovetto A., Petrucciani N. Neoadjuvant therapy for pancreatic cancer. Updates Surg. 2022; 74 (1): 35–42. https://doi.org/10.1007/s13304-021-01186-1</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Seufferlein T., Uhl W., Kornmann M. et al. Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX) – a randomized phase II trial of the AIO pancreatic cancer group. Ann. Oncol. 2023; 34 (1): 91–100. https://doi.org/10.1016/j.annonc.2022.09.161</mixed-citation><mixed-citation xml:lang="en">Seufferlein T., Uhl W., Kornmann M. et al. Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX) – a randomized phase II trial of the AIO pancreatic cancer group. Ann. Oncol. 2023; 34 (1): 91–100. https://doi.org/10.1016/j.annonc.2022.09.161</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ghaneh P., Palmer D., Cicconi S. et al. Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline resectable pancreatic cancer (ESPAC5): a four-arm, multicentre, randomised, phase 2 trial. Lancet Gastroenterol. Hepatol. 2023; 8 (2): 157–168. https://doi.org/10.1016/S2468-1253(22)00348-X</mixed-citation><mixed-citation xml:lang="en">Ghaneh P., Palmer D., Cicconi S. et al. Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline resectable pancreatic cancer (ESPAC5): a four-arm, multicentre, randomised, phase 2 trial. Lancet Gastroenterol. Hepatol. 2023; 8 (2): 157–168. https://doi.org/10.1016/S2468-1253(22)00348-X</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">NCCN Guidelines for Pancreatic Adenocarcinoma. V.1., 2023.</mixed-citation><mixed-citation xml:lang="en">NCCN Guidelines for Pancreatic Adenocarcinoma. V.1., 2023.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Lee E.S., Lee J.M. Imaging diagnosis of pancreatic cancer: a state-of-the-art review. Wld J. Gastroenterol. 2014; 20 (24): 7864–7877. https://doi.org/10.3748/wjg.v20.i24.7864</mixed-citation><mixed-citation xml:lang="en">Lee E.S., Lee J.M. Imaging diagnosis of pancreatic cancer: a state-of-the-art review. Wld J. Gastroenterol. 2014; 20 (24): 7864–7877. https://doi.org/10.3748/wjg.v20.i24.7864</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kim Y.K., Lee M.W., Lee W.J. et al. Diagnostic Accuracy and Sensitivity of Diffusion-Weighted and of Gadoxetic Acid-Enhanced 3-T MR Imaging Alone or in Combination in the Detection of Small Liver Metastasis (≤1.5 cm in Diameter). Invest. Radiol. 2012; 47 (3): 159–66. https://doi.org/10.1097/rli.0b013e31823a1495</mixed-citation><mixed-citation xml:lang="en">Kim Y.K., Lee M.W., Lee W.J. et al. Diagnostic Accuracy and Sensitivity of Diffusion-Weighted and of Gadoxetic Acid-Enhanced 3-T MR Imaging Alone or in Combination in the Detection of Small Liver Metastasis (≤1.5 cm in Diameter). Invest. Radiol. 2012; 47 (3): 159–66. https://doi.org/10.1097/rli.0b013e31823a1495</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Кармазановский Г.Г. Опухоли поджелудочной железы солидной структуры: стадирование и резектабельность, критерии оценки прогрессирования опухолевого процесса после хирургического лечения (лекция, часть 2). Медицинская визуализация. 2016; 5: 43–49.</mixed-citation><mixed-citation xml:lang="en">Karmazanovsky G.G. Solid Pancreatic Tumors: Staging and Resectability, Criteria for Evaluation of Tumor Progression after Surgical Treatment (Lecture, Part 2). Medical Visualization. 2016; 5: 43–49. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Шима В., Кауэлблингер К. Аденокарцинома поджелудочной железы: выявление, определение стадии и дифференциальная диагностика. Медицинская визуализация. 2015; 5: 52–72.</mixed-citation><mixed-citation xml:lang="en">Schima W., Koelblmger C. Pancreatic Adenocarcinoma: Detection, Staging and Differential Diagnosis. Medical Visualization. 2015; 5: 52–72. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ветшева Н.Н. Дооперационная диагностика солидных опухолей поджелудочной железы: обзор литературы. Медицинская визуализация. 2016; 5: 50–58.</mixed-citation><mixed-citation xml:lang="en">Vetsheva N.N. Preoperative Diagnosis of Solid Pancreatic Mass: Literature Review. Medical Visualization. 2016; 5: 50–58. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kamisawa T., Takuma K., Anjiki H. et al. Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion-weighted MRI. Am. J. Gastroenterol. 2010; 105 (8): 1870–1875. https://doi.org/10.1038/ajg.2010.87</mixed-citation><mixed-citation xml:lang="en">Kamisawa T., Takuma K., Anjiki H. et al. Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion-weighted MRI. Am. J. Gastroenterol. 2010; 105 (8): 1870–1875. https://doi.org/10.1038/ajg.2010.87</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Uzunoglu F.G., Welte M.-N., Gavazzi F. et al. Evaluation of the MDACC clinical classification system for pancreatic cancer patients in an European multicenter cohort. Eur. J. Surg. Oncol. 2019; 45 (5): 793–799. https://doi.org/10.1016/j.ejso.2018.12.012</mixed-citation><mixed-citation xml:lang="en">Uzunoglu F.G., Welte M.-N., Gavazzi F. et al. Evaluation of the MDACC clinical classification system for pancreatic cancer patients in an European multicenter cohort. Eur. J. Surg. Oncol. 2019; 45 (5): 793–799. https://doi.org/10.1016/j.ejso.2018.12.012</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Sohal D.P.S., Kennedy E.B., Cinar P. et al. Metastatic Pancreatic Cancer: ASCO Guideline Update. J. Clin. Oncol. 2020; 38 (27): 3217–3230. https://doi.org/10.1200/JCO.20.01364</mixed-citation><mixed-citation xml:lang="en">Sohal D.P.S., Kennedy E.B., Cinar P. et al. Metastatic Pancreatic Cancer: ASCO Guideline Update. J. Clin. Oncol. 2020; 38 (27): 3217–3230. https://doi.org/10.1200/JCO.20.01364</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Isaji S., Mizuno S., Windsor J.A. et al. International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017. Pancreatology. 2018; 18 (1): 2–11. https://doi.org/10.1016/j.pan.2017.11.011</mixed-citation><mixed-citation xml:lang="en">Isaji S., Mizuno S., Windsor J.A. et al. International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017. Pancreatology. 2018; 18 (1): 2–11. https://doi.org/10.1016/j.pan.2017.11.011</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Покатаев И.А., Гладков О.А., Загайнов В.Е., Кудашкин Н.Е., Кучин Д.М., Лядов В.К. и др. Практические рекомендации по лекарственному лечению рака поджелудочной железы. Злокачественные опухоли: Практические рекомендации RUSSCO #3s2, 2022; 12: 530–544. https://doi.org/10.18027/2224-5057-2022-12-3s2-530-544</mixed-citation><mixed-citation xml:lang="en">Pokataev I.A., Gladkov O.A., Zagainov V.E. et al. Practical recommendations for drug treatment of pancreatic cancer. Malignant tumors: Practical recommendations RUSSCO #3s2, 2022; 12: 530–544. https://doi.org/10.18027/2224-5057-2022-12-3s2-530-544 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Fujita T., Nakagohri T., Gotohda N. et al. Evaluation of the prognostic factors and significance of lymph node status in invasive ductal carcinoma of the body or tail of the pancreas. Pancreas. 2010; 39 (1): e48–54. https://doi.org/10.1097/MPA.0b013e3181bd5cfa</mixed-citation><mixed-citation xml:lang="en">Fujita T., Nakagohri T., Gotohda N. et al. Evaluation of the prognostic factors and significance of lymph node status in invasive ductal carcinoma of the body or tail of the pancreas. Pancreas. 2010; 39 (1): e48–54. https://doi.org/10.1097/MPA.0b013e3181bd5cfa</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Kanda M., Fujii T., Nagai S. et al. Pattern of lymph node metastasis spread in pancreatic cancer. Pancreas. 2011; 40: 951–955. https://doi.org/10.1097/MPA.0b013e3182148342</mixed-citation><mixed-citation xml:lang="en">Kanda M., Fujii T., Nagai S. et al. Pattern of lymph node metastasis spread in pancreatic cancer. Pancreas. 2011; 40: 951–955. https://doi.org/10.1097/MPA.0b013e3182148342</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Sergeant G., Melloul E., Lesurtel M. et al. Extended lymphadenectomy in patients with pancreatic cancer is debatable. Wld J. Surg. 2013; 37 (8): 1782–1788. https://doi.org/10.1007/s00268-013-2064-z</mixed-citation><mixed-citation xml:lang="en">Sergeant G., Melloul E., Lesurtel M. et al. Extended lymphadenectomy in patients with pancreatic cancer is debatable. Wld J. Surg. 2013; 37 (8): 1782–1788. https://doi.org/10.1007/s00268-013-2064-z</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Zacharias T., Jaeck D., Oussoultzoglou E. et al. Impact of lymph node involvement on long-term survival after R0 pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas. J. Gastrointest. Surg. 2007; 11: 350–356. https://doi.org/10.1007/s11605-007-0113-3</mixed-citation><mixed-citation xml:lang="en">Zacharias T., Jaeck D., Oussoultzoglou E. et al. Impact of lymph node involvement on long-term survival after R0 pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas. J. Gastrointest. Surg. 2007; 11: 350–356. https://doi.org/10.1007/s11605-007-0113-3</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Henne-Bruns D., Vogel I., Lüttges J. et al. Surgery for ductal adenocarcinoma of the pancreatic head: staging, complications, and survival after regional versus extended lymphadenectomy. Wld J. Surg. 2000; 24 (5): 595–601; discussion 601–602. https://doi.org/10.1007/s002689910089</mixed-citation><mixed-citation xml:lang="en">Henne-Bruns D., Vogel I., Lüttges J. et al. Surgery for ductal adenocarcinoma of the pancreatic head: staging, complications, and survival after regional versus extended lymphadenectomy. Wld J. Surg. 2000; 24 (5): 595–601; discussion 601–602. https://doi.org/10.1007/s002689910089</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Murakami Y., Uemura K., Sudo T. et al. Prognostic factors after surgical resection for intrahepatic, hilar, and distal cholangiocarcinoma. Ann. Surg. Oncol. 2011; 18 (3): 651–658. https://doi.org/10.1245/s10434-010-1325-4</mixed-citation><mixed-citation xml:lang="en">Murakami Y., Uemura K., Sudo T. et al. Prognostic factors after surgical resection for intrahepatic, hilar, and distal cholangiocarcinoma. Ann. Surg. Oncol. 2011; 18 (3): 651–658. https://doi.org/10.1245/s10434-010-1325-4</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Henne-Bruns D., Vogel I., Lüttges J. et al. Ductal adenocarcinoma of the pancreas head: survival after regional versus extended lymphadenectomy. Hepatogastroenterology. 1998; 45 (21): 855–866. PMID: 9684147</mixed-citation><mixed-citation xml:lang="en">Henne-Bruns D., Vogel I., Lüttges J. et al. Ductal adenocarcinoma of the pancreas head: survival after regional versus extended lymphadenectomy. Hepatogastroenterology. 1998; 45 (21): 855–866. PMID: 9684147</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Masui T., Kubota T., Aoki K. et al. Long-term survival after resection of pancreatic ductal adenocarcinoma with para-aortic lymph node metastasis: case report. Wld J. Surg. Oncol. 2013; 11 (1): 195. https://doi.org/10.1186/1477-7819-11-195</mixed-citation><mixed-citation xml:lang="en">Masui T., Kubota T., Aoki K. et al. Long-term survival after resection of pancreatic ductal adenocarcinoma with para-aortic lymph node metastasis: case report. Wld J. Surg. Oncol. 2013; 11 (1): 195. https://doi.org/10.1186/1477-7819-11-195</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Kaťuchová J., Bober J., Kaťuch V., Radoňak J. Significance of lymph node micrometastasis in pancreatic cancer patients. Eur. Surg. Res. 2012; 48 (1): 10–15. https://doi.org/10.1159/000334171</mixed-citation><mixed-citation xml:lang="en">Kaťuchová J., Bober J., Kaťuch V., Radoňak J. Significance of lymph node micrometastasis in pancreatic cancer patients. Eur. Surg. Res. 2012; 48 (1): 10–15. https://doi.org/10.1159/000334171</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Ishikawa O., Ohhigashi H., Sasaki Y. et al. Practical usefulness of lymphatic and connective tissue clearance for the carcinoma of the pancreas head. Ann. Surg. 1988; 208 (2): 215–220. https://doi.org/10.1097/00000658-198808000-00014</mixed-citation><mixed-citation xml:lang="en">Ishikawa O., Ohhigashi H., Sasaki Y. et al. Practical usefulness of lymphatic and connective tissue clearance for the carcinoma of the pancreas head. Ann. Surg. 1988; 208 (2): 215–220. https://doi.org/10.1097/00000658-198808000-00014</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Nimura Y., Nagino M., Takao S. et al. Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas: Long-term results of a japanese multicenter randomized controlled trial. J. Hepatobiliary. Pancreat. Sci. 2012; 19: 230–241. https://doi.org/10.1007/s00534-011-0466-6</mixed-citation><mixed-citation xml:lang="en">Nimura Y., Nagino M., Takao S. et al. Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas: Long-term results of a japanese multicenter randomized controlled trial. J. Hepatobiliary. Pancreat. Sci. 2012; 19: 230–241. https://doi.org/10.1007/s00534-011-0466-6</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Doi R., Kami K., Ito D. et al. Prognostic implication of para-aortic lymph node metastasis in resectable pancreatic cancer. Wld J. Surg. 2007; 31 (1): 147–154. https://doi.org/10.1007/s00268-005-0730-5</mixed-citation><mixed-citation xml:lang="en">Doi R., Kami K., Ito D. et al. Prognostic implication of para-aortic lymph node metastasis in resectable pancreatic cancer. Wld J. Surg. 2007; 31 (1): 147–154. https://doi.org/10.1007/s00268-005-0730-5</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011; 14: 101–112. https://doi.org/10.1007/s10120-011-0041-5</mixed-citation><mixed-citation xml:lang="en">Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011; 14: 101–112. https://doi.org/10.1007/s10120-011-0041-5</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Базин И.С., Покатаев И.А., Попова А.С., Базина И.В., Чихарева Я.Е. Место химиотерапии в лечении локализованного рака поджелудочной железы. Злокачественные опухоли. 2016; 4 (спецвыпуск 1): 20–25. https://doi.org/10.18027/2224-5057-2016-4s1-20-25</mixed-citation><mixed-citation xml:lang="en">Bazin I.S., Pokataev I.A., Popova A.S. et al. The place of chemotherapy in the treatment of localized pancreatic cancer. Malignant tumors. 2016; 4 (special issue 1): 20–25. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Lambert A., Schwarz L., Ducreux M., Conroy T. Neoadjuvant Treatment Strategies in Resectable Pancreatic Cancer. Cancers (Basel). 2021; 13 (18): 4724. https://doi.org/10.3390/cancers13184724</mixed-citation><mixed-citation xml:lang="en">Lambert A., Schwarz L., Ducreux M., Conroy T. Neoadjuvant Treatment Strategies in Resectable Pancreatic Cancer. Cancers (Basel). 2021; 13 (18): 4724. https://doi.org/10.3390/cancers13184724</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Springfeld C., Ferrone C.R., Katz M.H.G. et al. Neoadjuvant therapy for pancreatic cancer. Nat. Rev. Clin. Oncol. 2023; 20 (5): 318–337. https://doi.org/10.1038/s41571-023-00746-1</mixed-citation><mixed-citation xml:lang="en">Springfeld C., Ferrone C.R., Katz M.H.G. et al. Neoadjuvant therapy for pancreatic cancer. Nat. Rev. Clin. Oncol. 2023; 20 (5): 318–337. https://doi.org/10.1038/s41571-023-00746-1</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Katz M.H., Fleming J.B., Bhosale P. et al. Response of borderline resectable pancreatic cancer to neoadjuvant therapy is not reflected by radiographic indicators. Cancer. 2012; 118 (23): 5749–5756. https://doi.org/10.1002/cncr.27636</mixed-citation><mixed-citation xml:lang="en">Katz M.H., Fleming J.B., Bhosale P. et al. Response of borderline resectable pancreatic cancer to neoadjuvant therapy is not reflected by radiographic indicators. Cancer. 2012; 118 (23): 5749–5756. https://doi.org/10.1002/cncr.27636</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Ferrone C.R., Marchegiani G., Hong T.S. et al. Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer. Ann. Surg. 2015; 261: 12–17. https://doi.org/10.1097/SLA.0000000000000867</mixed-citation><mixed-citation xml:lang="en">Ferrone C.R., Marchegiani G., Hong T.S. et al. Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer. Ann. Surg. 2015; 261: 12–17. https://doi.org/10.1097/SLA.0000000000000867</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Zins M., Matos C., Cassinotto C. Pancreatic Adenocarcinoma Staging in the Era of Preoperative Chemotherapy and Radiation Therapy. Radiology. 2018; 287 (2): 374–390. https://doi.org/10.1148/radiol.2018171670</mixed-citation><mixed-citation xml:lang="en">Zins M., Matos C., Cassinotto C. Pancreatic Adenocarcinoma Staging in the Era of Preoperative Chemotherapy and Radiation Therapy. Radiology. 2018; 287 (2): 374–390. https://doi.org/10.1148/radiol.2018171670</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Chen X., Oshima K., Schott D. et al. Assessment of treatment response during chemoradiation therapy for pancreatic cancer based on quantitative radiomic analysis of daily CTs: An exploratory study. PLoS One. 2017; 12 (6): e0178961. https://doi.org/10.1371/journal.pone.0178961</mixed-citation><mixed-citation xml:lang="en">Chen X., Oshima K., Schott D. et al. Assessment of treatment response during chemoradiation therapy for pancreatic cancer based on quantitative radiomic analysis of daily CTs: An exploratory study. PLoS One. 2017; 12 (6): e0178961. https://doi.org/10.1371/journal.pone.0178961</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Navez J., Bouchart C., Lorenzo D. et al. What Should Guide the Performance of Venous Resection During Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma with Venous Contact? Ann. Surg. Oncol. 2021; 28 (11): 6211–6222. https://doi.org/10.1245/s10434-020-09568-2.</mixed-citation><mixed-citation xml:lang="en">Navez J., Bouchart C., Lorenzo D. et al. What Should Guide the Performance of Venous Resection During Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma with Venous Contact? Ann. Surg. Oncol. 2021; 28 (11): 6211–6222. https://doi.org/10.1245/s10434-020-09568-2.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Barreto S.G., Loveday B., Windsor J.A., Pandanaboyana S. Detecting tumour response and predicting resectability after neoadjuvant therapy for borderline resectable and locally advanced pancreatic cancer. ANZ J. Surg. 2019; 89 (5): 481–487. https://doi.org/10.1111/ans.14764</mixed-citation><mixed-citation xml:lang="en">Barreto S.G., Loveday B., Windsor J.A., Pandanaboyana S. Detecting tumour response and predicting resectability after neoadjuvant therapy for borderline resectable and locally advanced pancreatic cancer. ANZ J. Surg. 2019; 89 (5): 481–487. https://doi.org/10.1111/ans.14764</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Yang R., Lu M., Qian X. et al. Diagnostic accuracy of EUS and CT of vascular invasion in pancreatic cancer: a systematic review. J. Cancer. Res. Clin. Oncol. 2014; 140 (12): 2077–2086. https://doi.org/10.1007/s00432-014-1728-x</mixed-citation><mixed-citation xml:lang="en">Yang R., Lu M., Qian X. et al. Diagnostic accuracy of EUS and CT of vascular invasion in pancreatic cancer: a systematic review. J. Cancer. Res. Clin. Oncol. 2014; 140 (12): 2077–2086. https://doi.org/10.1007/s00432-014-1728-x</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Zimmermann C., Distler M., Jentsch C. et al. Evaluation of response using FDG-PET/CT and diffusion weighted MRI after radiochemotherapy of pancreatic cancer: a non-randomized, monocentric phase II clinical trial-PaCa-DD-041 (Eudra-CT 2009-011968-11). Strahlenther. Onkol. 2021; 197 (1): 19–26. https://doi.org/10.1007/s00066-020-01654-4</mixed-citation><mixed-citation xml:lang="en">Zimmermann C., Distler M., Jentsch C. et al. Evaluation of response using FDG-PET/CT and diffusion weighted MRI after radiochemotherapy of pancreatic cancer: a non-randomized, monocentric phase II clinical trial-PaCa-DD-041 (Eudra-CT 2009-011968-11). Strahlenther. Onkol. 2021; 197 (1): 19–26. https://doi.org/10.1007/s00066-020-01654-4</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Nishiofuku H., Tanaka T., Marugami N. et al. Increased tumour ADC value during chemotherapy predicts improved survival in unresectable pancreatic cancer. Eur. Radiol. 2016; 26 (6): 1835–1842. https://doi.org/10.1007/s00330-015-3999-2</mixed-citation><mixed-citation xml:lang="en">Nishiofuku H., Tanaka T., Marugami N. et al. Increased tumour ADC value during chemotherapy predicts improved survival in unresectable pancreatic cancer. Eur. Radiol. 2016; 26 (6): 1835–1842. https://doi.org/10.1007/s00330-015-3999-2</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Cozzi L., Comito T., Fogliata A. et al. Computed tomography based radiomic signature as predictive of survival and local control after stereotactic body radiation therapy in pancreatic carcinoma. PLoS One. 2019; 14 (1): e0210758. https://doi.org/10.1371/journal.pone.0210758</mixed-citation><mixed-citation xml:lang="en">Cozzi L., Comito T., Fogliata A. et al. Computed tomography based radiomic signature as predictive of survival and local control after stereotactic body radiation therapy in pancreatic carcinoma. PLoS One. 2019; 14 (1): e0210758. https://doi.org/10.1371/journal.pone.0210758</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Nasief H., Hall W., Zheng C. et al. Improving Treatment Response Prediction for Chemoradiation Therapy of Pancreatic Cancer Using a Combination of Delta-Radiomics and the Clinical Biomarker CA19-9. Front. Oncol. 2020; 9: 1464. https://doi.org/10.3389/fonc.2019.01464</mixed-citation><mixed-citation xml:lang="en">Nasief H., Hall W., Zheng C. et al. Improving Treatment Response Prediction for Chemoradiation Therapy of Pancreatic Cancer Using a Combination of Delta-Radiomics and the Clinical Biomarker CA19-9. Front. Oncol. 2020; 9: 1464. https://doi.org/10.3389/fonc.2019.01464</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Ciaravino V., Cardobi N., De Robertis R. et al. CT Texture Analysis of Ductal Adenocarcinoma Downstaged After Chemotherapy. Anticancer Res. 2018; 38 (8): 4889–4895. https://doi.org/10.21873/anticanres.12803</mixed-citation><mixed-citation xml:lang="en">Ciaravino V., Cardobi N., De Robertis R. et al. CT Texture Analysis of Ductal Adenocarcinoma Downstaged After Chemotherapy. Anticancer Res. 2018; 38 (8): 4889–4895. https://doi.org/10.21873/anticanres.12803</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Chen F., Zhou Y., Qi X. et al. CT texture analysis for the presurgical prediction of superior mesenteric-portal vein invasion in pancreatic ductal adenocarcinoma: comparison with CT imaging features. Clin. Radiol. 2021; 76 (5): 358–366. https://doi.org/10.1016/j.crad.2021.01.003</mixed-citation><mixed-citation xml:lang="en">Chen F., Zhou Y., Qi X. et al. CT texture analysis for the presurgical prediction of superior mesenteric-portal vein invasion in pancreatic ductal adenocarcinoma: comparison with CT imaging features. Clin. Radiol. 2021; 76 (5): 358–366. https://doi.org/10.1016/j.crad.2021.01.003</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Rigiroli F., Hoye J., Lerebours R. et al. CT Radiomic Features of Superior Mesenteric Artery Involvement in Pancreatic Ductal Adenocarcinoma: A Pilot Study. Radiology. 2021; 301 (3): 610–622. https://doi.org/10.1148/radiol.2021210699</mixed-citation><mixed-citation xml:lang="en">Rigiroli F., Hoye J., Lerebours R. et al. CT Radiomic Features of Superior Mesenteric Artery Involvement in Pancreatic Ductal Adenocarcinoma: A Pilot Study. Radiology. 2021; 301 (3): 610–622. https://doi.org/10.1148/radiol.2021210699</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Bian Y., Jiang H., Ma C. et al. Performance of CT-based radiomics in diagnosis of superior mesenteric vein resection margin in patients with pancreatic head cancer. Abdom. Radiol. (NY). 2020; 45 (3): 759–773. https://doi.org/10.1007/s00261-019-02401-9</mixed-citation><mixed-citation xml:lang="en">Bian Y., Jiang H., Ma C. et al. Performance of CT-based radiomics in diagnosis of superior mesenteric vein resection margin in patients with pancreatic head cancer. Abdom. Radiol. (NY). 2020; 45 (3): 759–773. https://doi.org/10.1007/s00261-019-02401-9</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
