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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1448</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1448</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЕРДЦЕ И СОСУДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEART AND VESSELS</subject></subj-group></article-categories><title-group><article-title>Оценка интракардиальной гемодинамики у детей до 1 года с дефектом межпредсердной перегородки</article-title><trans-title-group xml:lang="en"><trans-title>Evaluation of intracardial hemodynamics in children under 1 year of age with atrial septal defect</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0513-9012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соколов Александр Анатольевич – доктор мед. наук, профессор, заведующий лабораторией ультразвуковых и функциональных методов исследования НИИ кардиологии Томского национального исследовательского медицинского центра РАН, Томск</p></bio><bio xml:lang="en"><p>Alexander A. Sokolov – Doct. of Sci. (Med.), Professor, Head of the Department of Functional and Laboratory Diagnostics, Cardiology research Institute, Tomsk National medical research Center of the Russian Academy of Sciences, Tomsk</p></bio><email xlink:type="simple">falco16@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4023-455X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егунов</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Egunov</surname><given-names>О. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Егунов Олег Анатольевич – канд. мед. наук, врач сердечно-сосудистый хирург, научный сотрудник отделения сердечно-сосудистой хирургии НИИ кардиологии Томского национального исследовательского медицинского центра РАН, Томск</p></bio><bio xml:lang="en"><p>Оleg A. Egunov – Cand. of Sci. (Med.), cardiovascular surgeon, researcher, Department of Cardiovascular Surgery, Cardiology research Institute, Tomsk National medical research Center of the Russian Academy of Sciences, Tomsk</p></bio><email xlink:type="simple">egunov_oleg@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6531-7223</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сморгон</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smorgon</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сморгон Андрей Владимирович – младший научный сотрудник, сотрудник лаборатории ультразвуковых и функциональных методов исследований НИИ кардиологии Томского национального исследовательского медицинского центра РАН, Томск</p></bio><bio xml:lang="en"><p>Andrey V. Smorgon – Junior Researcher, employee of the laboratory of ultrasound and functional research methods, Cardiology research Institute, Tomsk National medical research Center of the Russian Academy of Sciences, Tomsk</p></bio><email xlink:type="simple">sav.ssmu@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0493-4762</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кожанов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozhanov</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кожанов Роман Сергеевич – врач сердечно-сосудистый хирург, аспирант отделения сердечно-сосудистой хирургии НИИ кардиологии Томского национального исследовательского медицинского центра РАН, Томск</p></bio><bio xml:lang="en"><p>Roman S. Kozhanov – postgraduate student of the Department of Cardiovascular Surgery, cardiovascular surgeon, Cardiology research Institute, Tomsk National medical research Center of the Russian Academy of Sciences, Tomsk</p></bio><email xlink:type="simple">romankozhanoff@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ кардиологии Томского национального исследовательского медицинского центра РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Cardiology research Institute, Tomsk National medical research Center of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>23</day><month>07</month><year>2024</year></pub-date><volume>28</volume><issue>3</issue><fpage>99</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Соколов А.А., Егунов О.А., Сморгон А.В., Кожанов Р.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Соколов А.А., Егунов О.А., Сморгон А.В., Кожанов Р.С.</copyright-holder><copyright-holder xml:lang="en">Sokolov A.A., Egunov О.A., Smorgon A.V., Kozhanov R.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1448">https://medvis.rdsmedia.ru/jour/article/view/1448</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: оценить внутрисердечную гемодинамику и определить необходимость ранней коррекции дефекта межпредсердной перегородки (ДМПП) у детей первого года жизни.  </p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование были включены пациенты, наблюдавшиеся с 2010 по 2021 г. 1-я группа была сформирована из детей в возрасте младше 12 мес с диагнозом ДМПП и наблюдавшихся следующие 4 года до его интервенционного или хирургического устранения. Во 2-ю группу (контроля) вошли здоровые дети соответствующего возраста. Всем пациентам выполнялось эхокардиографическое исследование с оценкой основных показателей гемодинамики и интракардиальных структур.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В 1-ю группу включено 887 детей с ДМПП, в группу контроля вошло 887 здоровых детей. Возраст пациентов, включенных в исследование, составлял 6 ± 2,6 мес для 1-й группы и 6 ± 2,5 мес для 2-й. Было обнаружено, что у детей, имеющих ДМПП, первым проявлением гемодинамических сдвигов была дилатация правого желудочка, а затем дилатация правого предсердия, что сопровождалось повышением давления в малом круге кровообращения и дефицитом массы тела. У 11% пациентов происходило спонтанное закрытие ДМПП в течение первого года жизни. Почти 20% пациентов младше 6 мес имели клинико-гемодинамические показания к хирургическому лечению ДМПП.</p></sec><sec><title>Выводы</title><p>Выводы. Показания к закрытию ДМПП у детей до года необходимо определять с учетом клинических, анатомических и гемодинамических показателей.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: evaluation of the intracardiac hemodynamics and determination indications for early correction of the atrial septal defect in children before 1 year age.</p></sec><sec><title>Methods</title><p>Methods. The study included patients observed from 2010 to 2021. The first group was formed from children under the age of 12 months with ASD and were observed for the next 4 years until its interventional or surgical elimination. The second group included healthy children of the appropriate age. All patients underwent an echocardiographic (ECHO) study with assessment of the main parameters of hemodynamics and intracardial structures.</p></sec><sec><title>Results</title><p>Results. The first group included 887 children with ASD, the control group included 887 healthy children. The age of the patients included in the study was 6 ± 2.6 months. for group I and 6 ± 2.5 months. for the second one. It was found that in young children with ASD, the first manifestation of hemodynamic changes was dilatation of the right ventricle, then the right atrium and finally dilatation of the pulmonary trunk, which was accompanied by an increase in pressure in the pulmonary circulation and weight loss. In 11% of patients, spontaneous closure of the ASD occurs within the first year of life. Almost 20% of patients are younger than 6 months. have clinical and hemodynamic indications for surgical treatment of ASD.</p></sec><sec><title>Conclusions</title><p>Conclusions. Indications for the atrial septal defect closure should be determined taking into account clinical, anatomical and hemodynamic parameters.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>врожденные пороки сердца</kwd><kwd>дефект межпредсердной перегородки</kwd><kwd>хирургическое лечение межпредсердной перегородки</kwd><kwd>гемодинамика дефекта межпредсердной перегородки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>congenital heart defects</kwd><kwd>atrial septal defect</kwd><kwd>surgical treatment of the atrial septal defect</kwd><kwd>hemodynamics of the atrial septal defect</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бокерия Л.А., Ким А.И., Зеленикин М.М. и др. Дефект межпредсердной перегородки. Клинические рекомендации. 2023. 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