<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1399</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1399</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРЮШНАЯ ПОЛОСТЬ И ЗАБРЮШИННОЕ ПРОСТРАНСТВО</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMEN AND RETROPERITONEAL</subject></subj-group></article-categories><title-group><article-title>Целиакия как редкий источник рецидивирующих тонкокишечных кровотечений. Обзор литературы и клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>Celiac disease as a rare source of recurrent small intestinal bleeding</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7431-4887</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кортиева</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kortieva</surname><given-names>Alena T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кортиева Алена Таймуразовна – врач-эндоскопист 1-й квалификационной категории ГБУЗ “Краевая клиническая больница №2”, Краснодар</p></bio><bio xml:lang="en"><p>Alena T. Kortieva – Endoscopy department doctor, Regional Clinical Hospital No 2, Krasnodar</p></bio><email xlink:type="simple">kat_endo@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7862-8613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крушельницкий</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Krushelnitskiy</surname><given-names>Vladimir S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крушельницкий Владимир Станиславович – канд. мед. наук, первый заместитель главного врача, врач-эндоскопист высшей категории ГБУЗ “Краевая клиническая больница №2”; ассистент кафедры хирургии №3 ФПК и ППС ФГБОУ ВО “Кубанский государственный медицинский университет” Минздрава России, Краснодар</p></bio><bio xml:lang="en"><p>Vladimir S. Krushelnitskiy – Cand. of Sci. (Med.), endoscopist, First Deputy Chief Physician of Regional Clinical Hospital No 2; Assistant at the Department of Surgery No. 3, Kuban State Medical University, Krasnodar</p></bio><email xlink:type="simple">kvs-endo@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7862-8613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Габриэль</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gabriel</surname><given-names>Sergei A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ГБУЗ “Краевая клиническая больница №2” Минздрава Краснодарского края; 350012 Краснодар, ул. Красных партизан, д. 6, корп. 2, Российская ФедерацияФГБОУ ВО “Кубанский государственный медицинский университет” Минздрава России; 350063 Краснодар, ул. им. М. Седина, д. 4, Российская Федерация</p></bio><bio xml:lang="en"><p>Sergei A. Gabriel – Doct. of Sci. (Med.), Professor, endoscopist, Chief Physician of Regional Clinical Hospital No 2; Professor of the Department of Surgery No. 3, Kuban State Medical University, Krasnodar</p></bio><email xlink:type="simple">gabriel-sa@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5594-5739</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дынько</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Dynko</surname><given-names>Viktor Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дынько Виктор Юрьевич – канд. мед. наук, заведующий отделением эндоскопии, врач-эндоскопист высшей категории  ГБУЗ “Краевая клиническая больница №2”; доцент кафедры хирургии №3 ФПК и ППС ФГБОУ ВО “Кубанский государственный медицинский университет” Минздрава России, Краснодар</p></bio><bio xml:lang="en"><p>Viktor Yu. Dynko – Cand. of Sci. (Med.), Head of endoscopy department, endoscopist, Regional Clinical Hospital No 2; Associate Professor, Department of Surgery No. 3, Kuban State Medical University, Krasnodar</p></bio><email xlink:type="simple">dynko.viktor@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8788-0749</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гучетль</surname><given-names>А. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Guchetl</surname><given-names>Aleksandr Yа.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гучетль Александр Якубович – канд. мед. наук, руководитель центра эндоскопических методов диагностики и лечения, врач-эндоскопист высшей категории ГБУЗ “Краевая клиническая больница №2”; доцент кафедры Хирургии №3 ФПК и ППС ФГБОУ ВО “Кубанский государственный медицинский университет” Минздрава России, Краснодар</p></bio><bio xml:lang="en"><p>Aleksandr Yа. Guchetl – Cand. of Sci. (Med.), Head of center for endoscopic diagnostic and treatment methods, Regional Clinical Hospital No 2; Associate Professor, Department of Surgery No. 3, Kuban State Medical University, Krasnodar</p></bio><email xlink:type="simple">guchetl@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ “Краевая клиническая больница №2” Минздрава Краснодарского края; 350012 Краснодар, ул. Красных партизан, д. 6, корп. 2, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Institution “Regional Clinical Hospital No 2”; 6-2, Krasnykh Partizan str., Krasnodar 350012, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ “Краевая клиническая больница №2” Минздрава Краснодарского края; 350012 Краснодар, ул. Красных партизан, д. 6, корп. 2, Российская Федерация&#13;
ФГБОУ ВО “Кубанский государственный медицинский университет” Минздрава России; 350063 Краснодар, ул. им. М. Седина, д. 4, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Institution “Regional Clinical Hospital No 2”; 6-2, Krasnykh Partizan str., Krasnodar 350012, Russian Federation&#13;
Kuban State Medical University; 4, M. Sedina str., Krasnodar 350063, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>26</day><month>12</month><year>2023</year></pub-date><volume>28</volume><issue>2</issue><fpage>80</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кортиева А.Т., Крушельницкий В.С., Габриэль С.А., Дынько В.Ю., Гучетль А.Я., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Кортиева А.Т., Крушельницкий В.С., Габриэль С.А., Дынько В.Ю., Гучетль А.Я.</copyright-holder><copyright-holder xml:lang="en">Kortieva A.T., Krushelnitskiy V.S., Gabriel S.A., Dynko V.Y., Guchetl A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1399">https://medvis.rdsmedia.ru/jour/article/view/1399</self-uri><abstract><p>Цель исследования: изучение эффективности эндоскопических вмешательств при осложненной целиакии.Материал и методы. Проведен электронный поиск литературы с использованием баз данных PubMed, Medline, Cochrane Library. Описано клиническое наблюдение пациента с тонкокишечным кровотечением и целиакией. Результаты. В данный обзор литературы включены клинические наблюдения, ретроспективные исследования и обзоры литературы. Представлено клиническое наблюдение пациента, отмечавшего в течение 2 лет периодические выделения крови из анального канала. По данным эзофагогастродуоденоскопии выявлен эрозивный гастрит, осложненный кровотечением (источник не выявлен) с подозрением на целиакию. По данным гистологического заключения целиакия исключена. При госпитализации решено выполнить капсульную эндоскопию с баллонно-ассистированной энтероскопией и последующим взятием биопсии. По данным комплексного эндоскопического исследования тонкой кишки выявлены разнокалиберные дефекты слизистой оболочки с признаками продолжающегося кровотечения. Выполнено эндоскопическое клипирование выявленных дефектов и взята биопсия. По результатам гистологического исследования диагностирована целиакия, осложненная тонкокишечным кровотечением. Заключение. Применение эндоскопических терапевтических методик позволяет избежать хирургических вмешательств, а также сохраняет качество жизни пациента.</p></abstract><trans-abstract xml:lang="en"><p>Aim: study of the effectiveness of endoscopic interventions in complicated celiac disease.Material and methods. An electronic literature search was performed using databases: PubMed, Medline, Cochrane Library. A clinical case of a patient with small intestinal bleeding and celiac disease is described.Results. This literature review includes case reports, retrospective studies, and literature reviews. Presented is a clinical case of a patient who noted periodic discharge of blood from the anal canal for 2 years. According to esophagogastroduodenoscopy, erosive gastritis was detected, complicated by bleeding (the source was not identified) with suspected celiac disease. According to the histological conclusion, celiac disease is excluded. During hospitalization, it was decided to perform capsule endoscopy with balloon-assisted enteroscopy followed by a biopsy. According to the data of a comprehensive endoscopic examination of the small intestine, various defects of the mucous membrane with signs of ongoing bleeding were revealed. Endoscopic clipping of the identified defects was performed and a biopsy was taken. According to the results of histological examination, celiac disease complicated by small intestinal bleeding was diagnosed.Conclusions. The use of endoscopic therapeutic techniques avoids surgical interventions, and preserves the quality of life of the patient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>целиакия</kwd><kwd>капсульная эндоскопия</kwd><kwd>тонкокишечные кровотечения</kwd><kwd>баллонно-ассистированная энтероскопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>celiac disease</kwd><kwd>capsular endoscopy</kwd><kwd>small intestine bleeding</kwd><kwd>balloon-assisted enteroscopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aziz I., Sanders D. S. Are we diagnosing too many people with coeliac disease? Proc. Nutr. Soc. 2012; 71 (4): 538–544. http://doi.org/10.1017/S0029665112000262</mixed-citation><mixed-citation xml:lang="en">Aziz I., Sanders D. S. Are we diagnosing too many people with coeliac disease? Proc. Nutr. Soc. 2012; 71 (4): 538–544. http://doi.org/10.1017/S0029665112000262</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Stevens F.M., McCarthy C.F. The endoscopic demonstration of coeliac disease. Endoscopy. 1976; 8 (4): 177–180. http://doi.org/10.1055/s-0028-1098406</mixed-citation><mixed-citation xml:lang="en">Stevens F.M., McCarthy C.F. The endoscopic demonstration of coeliac disease. Endoscopy. 1976; 8 (4): 177–180. http://doi.org/10.1055/s-0028-1098406</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Isakova I.A. Celiac and glutensensetive diseases. Crimean Therapeutic Journal. 2006; 2: 83–89. URL: https://cyberleninka.ru/article/n/tseliakiya-i-glyutenchuvstvitelnye-zabolevaniya (In Russian)</mixed-citation><mixed-citation xml:lang="en">Isakova I.A. Celiac and glutensensetive diseases. Crimean Therapeutic Journal. 2006; 2: 83–89. URL: https://cyberleninka.ru/article/n/tseliakiya-i-glyutenchuvstvitelnye-zabolevaniya (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chen Y., Aguirre A.D., Hsiung P.L. et al. Ultrahigh resolution optical coherence tomography of Barrett’s esophagus: preliminary descriptive clinical study correlating images with histology. Endoscopy. 2007; 39: 599-605. http://doi.org/10.1055/ s-2007-966648</mixed-citation><mixed-citation xml:lang="en">Chen Y., Aguirre A.D., Hsiung P.L. et al. Ultrahigh resolution optical coherence tomography of Barrett’s esophagus: preliminary descriptive clinical study correlating images with histology. Endoscopy. 2007; 39: 599-605. http://doi.org/10.1055/ s-2007-966648</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Oreshko L.S., Bakulin I.G., Avalueva E.B. et al. Modern understanding of adult celiac disease. Experimental and Clinical Gastroenterology. 2021; 4: 84-95. https://doi.org/10.31146/1682-8658-ecg-188-4-84-95 (In Russian)</mixed-citation><mixed-citation xml:lang="en">Oreshko L.S., Bakulin I.G., Avalueva E.B. et al. Modern understanding of adult celiac disease. Experimental and Clinical Gastroenterology. 2021; 4: 84-95. https://doi.org/10.31146/1682-8658-ecg-188-4-84-95 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Spada C., Riccioni M.E., Urgesi R., Costamagna G. Capsule endoscopy in celiac disease. Wld J. Gastroenterol. 2008; 14 (26): 4146–4151. https://doi.org/10.3748/wjg.14.4146</mixed-citation><mixed-citation xml:lang="en">Spada C., Riccioni M.E., Urgesi R., Costamagna G. Capsule endoscopy in celiac disease. Wld J. Gastroenterol. 2008; 14 (26): 4146–4151. https://doi.org/10.3748/wjg.14.4146</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gwiggner M., Patel P. An unusual case of obscure gastrointestinal bleeding in a patient with coeliac disease. Case reports in gastrointestinal medicine. 2011; 634684. https://doi.org/10.1155/2011/634684</mixed-citation><mixed-citation xml:lang="en">Gwiggner M., Patel P. An unusual case of obscure gastrointestinal bleeding in a patient with coeliac disease. Case reports in gastrointestinal medicine. 2011; 634684. https://doi.org/10.1155/2011/634684</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kimchi N.A., Broide E., Zehavi S. et al. Capsule endoscopy diagnosis of celiac disease and ileal tumors in a patient with melena of obscure origin. Isr. Med. Assoc. J. 2005; 7: 412–413.</mixed-citation><mixed-citation xml:lang="en">Kimchi N.A., Broide E., Zehavi S. et al. Capsule endoscopy diagnosis of celiac disease and ileal tumors in a patient with melena of obscure origin. Isr. Med. Assoc. J. 2005; 7: 412–413.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Dima A., Jurcut C., Manolache A. et al. Hemorrhagic Events in Adult Celiac Disease Patients. Case Report and Review of the Literature. J. Gastrointest. Liver Dis.(JGLD). 2018; 27(1): 93–99. https://doi.org/10.15403/jgld.2014.1121.271.cld</mixed-citation><mixed-citation xml:lang="en">Dima A., Jurcut C., Manolache A. et al. Hemorrhagic Events in Adult Celiac Disease Patients. Case Report and Review of the Literature. J. Gastrointest. Liver Dis.(JGLD). 2018; 27(1): 93–99. https://doi.org/10.15403/jgld.2014.1121.271.cld</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Packová B., Kunovský L., Eid M. et al. Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature. Adenokarcinom tenkého střeva diagnostikovaný pomocí video kapslové endoskopie u pacientky s celiakií: kazuistika a přehled literatury. Vnitr. Lek. 2020; 66 (7): 39–42. PMID: 33380133</mixed-citation><mixed-citation xml:lang="en">Packová B., Kunovský L., Eid M. et al. Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature. Adenokarcinom tenkého střeva diagnostikovaný pomocí video kapslové endoskopie u pacientky s celiakií: kazuistika a přehled literatury. Vnitr. Lek. 2020; 66 (7): 39–42. PMID: 33380133</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Mant M.J., Bain V.G., Maguire C.G. et al. Prevalence of occult gastrointestinal bleeding in celiac disease. Clin. Gastroenterol. Hepatol. 2006; 4 (4): 451–454. https://doi.org/10.1016/j.cgh.2005.12.010</mixed-citation><mixed-citation xml:lang="en">Mant M.J., Bain V.G., Maguire C.G. et al. Prevalence of occult gastrointestinal bleeding in celiac disease. Clin. Gastroenterol. Hepatol. 2006; 4 (4): 451–454. https://doi.org/10.1016/j.cgh.2005.12.010</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Pasha S.F., Hara A.K., Leighton J.A. Diagnostic evaluation and management of obscure gastrointestinal bleeding: a changing paradigm. Gastroenterol. Hepatol. (NY). 2009; 5 (12): 839–850. PMID: 20567529</mixed-citation><mixed-citation xml:lang="en">Pasha S.F., Hara A.K., Leighton J.A. Diagnostic evaluation and management of obscure gastrointestinal bleeding: a changing paradigm. Gastroenterol. Hepatol. (NY). 2009; 5 (12): 839–850. PMID: 20567529</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Hosoe N., Takabayashi K., Ogata H., Kanai T. Capsule endoscopy for small-intestinal disorders: Current status. Digestive Endoscopy. 2019; 31 (5): 498–507. https://doi.org/10.1111/den.13346</mixed-citation><mixed-citation xml:lang="en">Hosoe N., Takabayashi K., Ogata H., Kanai T. Capsule endoscopy for small-intestinal disorders: Current status. Digestive Endoscopy. 2019; 31 (5): 498–507. https://doi.org/10.1111/den.13346</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
