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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1369</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1369</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЕРДЦЕ И СОСУДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEART AND VESSELS</subject></subj-group></article-categories><title-group><article-title>Комплексная ультразвуковая оценка состояния комплекса интима-медиа брахиоцефальных артерий у пациентов с метаболическим синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Comprehensive ultrasound assessment of the state complex intima-media brachiocephalic arteries in patients with metabolic syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-3986-6586</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вахитова</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Vakhitova</surname><given-names>Aliya R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вахитова Алия Рустемовна – врач ультразвуковой диагностики ГБУЗ “Городская поликлиника № 64, филиал № 2 ДЗ города Москвы”, Москва</p></bio><bio xml:lang="en"><p>Aliya R. Vakhitova – ultrasound specialist, City Polyclinic No. 64 branch No. 2, Moscow Department of Healthcare, Moscow. </p></bio><email xlink:type="simple">aliafat@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5387-4367</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бердалин</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Berdalin</surname><given-names>Alexander B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бердалин Александр Берикович – канд. мед. наук, старший научный сотрудник ФГБУ “Федеральный центр мозга и нейротехнологий” ФМБА России, Москва</p></bio><bio xml:lang="en"><p>Alexander B. Berdalin – Cand. of Sci. (Med.), Senior Research assistant, “Federal Center of Brain Research and Neurotechnologies” of the Federal Medical Biological Agency, Moscow</p></bio><email xlink:type="simple">berdalin@fccps.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9690-8325</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лелюк</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Lelyuk</surname><given-names>Vladimir G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лелюк Владимир Геннадьевич – доктор мед. наук, профессор, руководитель отдела клинической и экспериментальной физиологии кровообращения ФГБУ “Федеральный центр мозга и нейротехнологий” ФМБА России; руководитель МПМЦ “Сосудистая клиника на Патриарших” Москва</p></bio><bio xml:lang="en"><p>Vladimir G. Lelyuk – Doct. of Sci. (Med.), Professor, Head of department clinical and experimental physiology of circulatory system, ultrasound and functional diagnostics, Federal center of brain research and neurotechnologies” of the Federal Medical Biological Agency; Head of Vascular Clinic on the Patriarchs, Moscow</p></bio><email xlink:type="simple">v.g.lelyuk@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8428-8037</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лелюк</surname><given-names>С. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Lelyuk</surname><given-names>Svetlana E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лелюк Светлана Эдуардовна – доктор мед. наук, профессор, руководитель МПМЦ “Сосудистая клиника на Патриарших”; профессор кафедры ультразвуковой диагностики ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России, Москва</p></bio><bio xml:lang="en"><p>Svetlana E. Lelyuk – Doct. of Sci. (Med.), Professor, Head of Vascular Clinic on the Patriarchs; Professor of the Department of Ultrasound Diagnostics, Russian Medical Academy of Continuing Professional, Moscow</p></bio><email xlink:type="simple">selelyuk@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ “Городская поликлиника № 64, филиал № 2 ДЗ города Москвы”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Polyclinic No. 64, branch No. 2 of the Moscow Department of Healthcare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ “Федеральный центр мозга и нейротехнологий” ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency (FMBA of Russia)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ “Федеральный центр мозга и нейротехнологий” ФМБА России; МПМЦ “Сосудистая клиника на Патриарших”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency (FMBA of Russia); Vascular Clinic on the Patriarchs</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ДПО “Российская медицинская академия непрерывного профессионального образования” Минздрава России; МПМЦ “Сосудистая клиника на Патриарших”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation; Vascular Clinic on the Patriarchs</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2024</year></pub-date><volume>28</volume><issue>2</issue><fpage>32</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Вахитова А.Р., Бердалин А.Б., Лелюк В.Г., Лелюк С.Э., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Вахитова А.Р., Бердалин А.Б., Лелюк В.Г., Лелюк С.Э.</copyright-holder><copyright-holder xml:lang="en">Vakhitova A.R., Berdalin A.B., Lelyuk V.G., Lelyuk S.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1369">https://medvis.rdsmedia.ru/jour/article/view/1369</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: комплексная ультразвуковая оценка состояния комплекса интима-медиа (КИМ) брахиоцефальных артерий у пациентов с метаболическим синдромом (МС).  </p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследовано 82 пациента, из них 62 пациента с МС и 20 практически здоровых лиц. Всем пациентам проводился биохимический анализ крови, УЗДС экстракраниальных отделов брахиоцефальных артерий с оценкой качественных и количественных характеристик КИМ бифуркации плечеголовного ствола (ПГС), общих сонных (ОСА) и позвоночных артерий (ПА).</p></sec><sec><title>Результаты</title><p>Результаты. У 100% пациентов с МС зафиксированы изменения эхоструктуры КИМ в виде патологической слоистости, у 9 (14,5%) пациентов – в виде гиперэхогенных включений. Толщина КИМ в бифуркации ПГС и ОСА у пациентов с МС статистически достоверно превышает аналогичный показатель у практически здоровых лиц и демонстрирует прямую корреляционную зависимость от компонентов МС. Модифицированный индекс Карнегана у пациентов с МС статистически значимо превышает аналогичный показатель у практически здоровых лиц и демонстрирует прямую корреляционную зависимость с толщиной КИМ, оцененной в разных сегментах брахиоцефальных артерий (ПГС k 0,356, правая ОСА k 0,718, левая ОСА k 0,846, в бифуркации ОСА справа k 0,431, слева k 0,519).</p></sec><sec><title>Заключение</title><p>Заключение. Комплексная ультразвуковая оценка состояния КИМ брахиоцефальных артерий у пациентов с МС позволяет получить комплекс качественных и количественных признаков, характерных для метаболической ангиопатии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. Comprehensive ultrasound assessment of the state complex intima-media (CIM) of brachiocephalic arteries in patients with metabolic syndrome (MS). </p></sec><sec><title>Materials and methods</title><p>Materials and methods. 82 patients were examined, including 62 patients with MS and 20 practically healthy individuals. All patients underwent biochemical blood analysis, ultrasound of the extracranial sections of the brachiocephalic arteries with an assessment of the qualitative and quantitative characteristics of CIM bifurcation of the brachiocephalic trunk (BCT), common carotid arteries (CCA) and vertebral arteries (VA).</p></sec><sec><title>Results</title><p>Results. 100% of patients with MS, changes in the echostructure of CIM were recorded in the form of pathological layering, 9 (14.5%) patients – in the form of hyperechogenic inclusions. Thickness of CIM in the bifurcation of BCT and CCA in patients with MS statistically significantly exceeds the same indicator in practically healthy persons and demonstrates direct correlation between the components of MS. The modified Carnegan index patients with MS is statistically significantly higher than the same indicator in practically healthy individuals and demonstrates direct correlation with the thickness of CIM estimated in different segments of the brachiocephalic arteries (BCT k 0.356, RCCA k 0.718, LCCA k 0.846, in the bifurcation of CCA on the right k 0.431, on the left k 0.519).</p></sec><sec><title>Conclusion</title><p>Conclusion. Comprehensive ultrasound assessment of the state brachiocephalic arteries in patients with MS allows us to obtain complex of qualitative and quantitative signs characteristic of metabolic angiopathy.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>метаболическая ангиопатия</kwd><kwd>патологическая слоистость</kwd><kwd>гиперэхогенные включения</kwd><kwd>толщина комплекса интима-медиа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic syndrome</kwd><kwd>metabolic angiopathy</kwd><kwd>pathological layering</kwd><kwd>hyperechoic inclusions</kwd><kwd>thickness of the complex intima-media</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мычка В.Б., Верткин А.Л., Вардаев Л.И., Дружилов М.А., Ипаткин Р.В., Калинкин А.Л., Кузнецова И.В., Кузнецова Т.Ю. 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