<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1323</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1323</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРЮШНАЯ ПОЛОСТЬ И ЗАБРЮШИННОЕ ПРОСТРАНСТВО</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMEN AND RETROPERITONEAL</subject></subj-group></article-categories><title-group><article-title>Лучевая диагностика в определении признаков возможного кровотечения из варикозно расширенных вен желудка (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostic imaging in determining the signs of possible bleeding from gastric varicose veins (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3218-8688</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ягубова</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yagubova</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ягубова Кира Владимировна – ассистент кафедры лучевой диагностики и терапии,</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Kira V. Yagubova – assistant of the radiology department,</p><p>house 1, Ostrivityanova str., Moscow 117997</p></bio><email xlink:type="simple">kira--95@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7284-4737</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юдин</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Yudin</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юдин Андрей Леонидович – доктор мед. наук, профессор, заведующий кафедрой лучевой диагностики и терапии,</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Andrey L. Yudin – Doct. of Sci. (Med.), professor, head of radiology department,</p><p>house 1, Ostrivityanova str., Moscow 117997</p></bio><email xlink:type="simple">prof_yudin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2203-989X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьева</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanas`eva</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Афанасьева Наталья Иосифовна – канд. мед. наук, доцент кафедры лучевой диагностики и терапии,</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Natalya I. Afanas`eva – Cand. of Sci. (Med.), associate professor, radiology department,</p><p>house 1, Ostrivityanova str., Moscow 117997</p></bio><email xlink:type="simple">x-rayrsmu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6020-9434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юматова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yumatova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юматова Елена Анатольевна – канд. мед. наук, доцент кафедры лучевой диагностики и терапии,</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Elena A. Yumatova – Cand. of Sci. (Med.), associate professor, radiology department, </p><p>house 1, Ostrivityanova str., Moscow 117997</p></bio><email xlink:type="simple">yumatova_ea@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>09</month><year>2023</year></pub-date><volume>28</volume><issue>1</issue><fpage>110</fpage><lpage>119</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ягубова К.В., Юдин А.Л., Афанасьева Н.И., Юматова Е.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ягубова К.В., Юдин А.Л., Афанасьева Н.И., Юматова Е.А.</copyright-holder><copyright-holder xml:lang="en">Yagubova K.V., Yudin A.L., Afanas`eva N.I., Yumatova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1323">https://medvis.rdsmedia.ru/jour/article/view/1323</self-uri><abstract><sec><title>Введение</title><p>Введение. Варикозное расширение вен желудка одна из частых причин желудочно-кишечных кровотечений у пациентов с портальной гипертензией. Кровотечение данной локализации имеет больший процент летального исхода и сложности в достижении гемостаза, чем кровотечение из варикозно расширенных вен пищевода. В данной статье рассмотрены этиология и основные аспекты патофизиологии портальной гипертензии, механизмы развития кровотечений, которые играют важную роль в профилактике осложнений. Достаточно подробно представлены венозный отток от желудка, варианты портосистемных коллатеральных анастомозов и типы варикозного расширения вен собственно желудка. Продемонстрированы преимущества и недостатки лучевых методов диагностики в оценке варикозно расширенных вен желудка и возможного прогнозирования риска кровотечения.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: проанализировать данные зарубежной и отечественной литературы о варикозно расширенных венах желудка, выявить критерии, определяющие риски кровотечения по данным методов лучевой диагностики.</p></sec><sec><title>Результаты</title><p>Результаты. Анализ зарубежной и отечественной литературы показал, что проблема диагностики и лечения варикозно расширенных вен желудка крайне актуальна и требует специального рассмотрения всевозможных ее аспектов. Существует множество методов диагностики с определенными преимуществами и недостатками. Но, на наш взгляд, возможности неинвазивных методов, особенно компьютерной томографии, в диагностике варикозно расширенных вен желудка и прогноза развития кровотечения из них недооценены и требуют дальнейшего изучения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Annotation</title><p>Annotation. Gastric varicose veins are one of the common causes of gastrointestinal bleeding in patients with portal hypertension. Bleeding of this localization has a greater percentage of death and difficulty in achieving hemostasis than bleeding from esophageal varices. This paper discusses the etiology and main aspects of the pathophysiology of portal hypertension, the mechanisms of bleeding, which play an important role in the prevention of complications prevention. The venous outflow from the stomach, variants of porto-systemic collateral anastomoses and types of varicose veins of the stomach itself are presented in sufficient detail. The advantages and disadvantages of diagnostic imaging in the assessment of gastric varicose veins and the possible prediction of the risk of bleeding are demonstrated.</p></sec><sec><title>Aim</title><p>Aim: to analyze the data of foreign and domestic literature on varicose veins of the stomach, to identify criteria that determine the risks of bleeding according to the methods of diagnostic imaging.</p></sec><sec><title>Results</title><p>Results. Analysis of foreign and domestic literature showed that the problem of diagnosing gastric varicose veins is extremely relevant and requires special consideration of all its various aspects. There are many diagnostic methods with certain advantages and disadvantages. But, in our opinion, the possibilities of non-invasive methods, especially computed tomography, in the diagnosis of varicose veins of the stomach and the prognosis of bleeding from them are underestimated and require further study.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>портальная гипертензия</kwd><kwd>варикозное расширение вен желудка</kwd><kwd>желудочно-кишечное кровотечение</kwd><kwd>лучевая диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>portal hypertension</kwd><kwd>gastric varicose veins</kwd><kwd>gastrointestinal bleeding</kwd><kwd>diagnostic imaging</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ивашкин В.Т., Маевская М.В., Жаркова М.С., Жигалова С.Б., Киценко Е.А., Манукьян Г.В., Трухманов А.С., Маев И.В., Тихонов И.Н., Деева Т.А. Клинические рекомендации Российского общества по изучению печени и Российской гастроэнтерологической ассоциации по диагностике и лечению фиброза и цирроза печени и их осложнений. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2021; 31 (6): 56–102. https://doi.org/10.22416/1382-4376-2021-31-6-56-102</mixed-citation><mixed-citation xml:lang="en">Ivashkin V.T., Maevskaya M.V., Zharkova M.S. et al. Clinical Recommendations of the Russian Scientific Liver Society and Russian Gastroenterological Association on Diagnosis and Treatment of Liver Fibrosis, Cirrhosis and Their Complications. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2021; 31 (6): 56–102. https://doi.org/10.22416/1382-4376-2021-31-6-56-102 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кляритская И.Л., Мошко Ю.А., Волков А.В., Максимова Е.В., Шелихова Е.О., Работягова Ю.С., Семенихина Е.В. Современные методы диагностики и лечения варикозных вен пищевода и желудка. Крымский терапевтический журнал. 2020; 1: 5–16.</mixed-citation><mixed-citation xml:lang="en">Kliaritskaia I.L., Moshko Y.A., Volkov A.V. et al. Modern methods for the diagnosis and management of esophagus and stomach varicose veins. Crimean Journal of Internal Diseases. 2020; 1: 5–16. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Marek T.A. Gastrointestinal bleeding. Endoscopy. 2001; 33 (11): 920–929. https://doi.org/10.1055/s-2001-17914</mixed-citation><mixed-citation xml:lang="en">Marek T.A. Gastrointestinal bleeding. Endoscopy. 2001; 33 (11): 920–929. https://doi.org/10.1055/s-2001-17914</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Garcia-Tsao G., Abraldes J.G., Berzigotti A., Bosch J. Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases. Hepatology. 2017: 65 (1): 310–335. https://doi.org/10.1002/hep.28906</mixed-citation><mixed-citation xml:lang="en">Garcia-Tsao G., Abraldes J.G., Berzigotti A., Bosch J. Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases. Hepatology. 2017: 65 (1): 310–335. https://doi.org/10.1002/hep.28906</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Christodoulou D., Tsianos E.V., Kortan P., Marcon N. Gastric and ectopic varices newer endoscopic options. Ann. Gastroentеrоl. 2007; 20 (2): 95–109. https://doi.org/10.1155/2007/407075</mixed-citation><mixed-citation xml:lang="en">Christodoulou D., Tsianos E.V., Kortan P., Marcon N. Gastric and ectopic varices newer endoscopic options. Ann. Gastroentеrоl. 2007; 20 (2): 95–109. https://doi.org/10.1155/2007/407075</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Жигалова С.Б., Манукьян Г.В., Шерцингер А.Г., Фандеев Е.Е., Семенова Т.С., Коршунов И.Б., Мартиросян Р.А. Прогностические критерии кровотечений из варикозно расширенных вен пищевода и желудка у больных портальной гипертензией. Анналы хирургической гепатологии. 2018; 23 (4): 76–85. https://doi.org/10.16931/1995-5464.2018476-85</mixed-citation><mixed-citation xml:lang="en">Zhigalova S.B., Manukiyan G.V., Shertsinger A.G. et al. Prognostic criteria of variceal bleeding in patients with portal hypertension. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2018; 23 (4): 76–85. https://doi.org/10.16931/1995-5464.2018476-85 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch J., Abraldes J.G., Berzigotti A., Garcia-Pagan J.C. Portal hypertension and gastrointestinal bleeding. Semin. Liver Dis. 2008; 28: 3–25. https://doi.org/10.1055/s-2008-1040318</mixed-citation><mixed-citation xml:lang="en">Bosch J., Abraldes J.G., Berzigotti A., Garcia-Pagan J.C. Portal hypertension and gastrointestinal bleeding. Semin. Liver Dis. 2008; 28: 3–25. https://doi.org/10.1055/s-2008-1040318</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chiva L.M., Magrina J. Abdominal and Pelvic Anatomy. 2018; 3–49. https://doi.org/10.1016/B978-0-323-42878-1.00002-X</mixed-citation><mixed-citation xml:lang="en">Chiva L.M., Magrina J. Abdominal and Pelvic Anatomy. 2018; 3–49. https://doi.org/10.1016/B978-0-323-42878-1.00002-X</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mihai F., Bar C., Savin M.L. et al. CT appearance of collateral pathways in portal hypertension. ECR 2011. C-0972. https://dx.doi.org/10.1594/ecr2011/C-0972</mixed-citation><mixed-citation xml:lang="en">Mihai F., Bar C., Savin M.L. et al. CT appearance of collateral pathways in portal hypertension. ECR 2011. C-0972. https://dx.doi.org/10.1594/ecr2011/C-0972</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Sarin S.K., Lahoti D., Saxena S.P. et al. Prevalence, classification and natural history of gastric varices: a longterm follow-up study in 568 portal hypertension patients. Hepatology. 1992; 16 (6): 1343–1349. https://doi.org/10.1002/hep.1840160607</mixed-citation><mixed-citation xml:lang="en">Sarin S.K., Lahoti D., Saxena S.P. et al. Prevalence, classification and natural history of gastric varices: a longterm follow-up study in 568 portal hypertension patients. Hepatology. 1992; 16 (6): 1343–1349. https://doi.org/10.1002/hep.1840160607</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Vine L., Subhani M., Acevedo J. Update on management of gastric varices. Wld J. Hepatol. 2019; 11: 250–260. https://doi.org/10.4254/wjh.v11.i3.250</mixed-citation><mixed-citation xml:lang="en">Vine L., Subhani M., Acevedo J. Update on management of gastric varices. Wld J. Hepatol. 2019; 11: 250–260. https://doi.org/10.4254/wjh.v11.i3.250</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Groszmann R.J., Bosch J., Grace N.D. et al. Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology. 1990; 99 (5): 1401–1407. https://doi.org/10.1016/0016-5085(90)91168-6</mixed-citation><mixed-citation xml:lang="en">Groszmann R.J., Bosch J., Grace N.D. et al. Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology. 1990; 99 (5): 1401–1407. https://doi.org/10.1016/0016-5085(90)91168-6</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Simonetto D.A., Liu M., Kamath P.S. Portal Hypertension and Related Complications: Diagnosis and Management. Mayo Clin. Proc. 2019; 94 (4): 714–726. https://doi.org/10.1016/j.mayocp.2018.12.020</mixed-citation><mixed-citation xml:lang="en">Simonetto D.A., Liu M., Kamath P.S. Portal Hypertension and Related Complications: Diagnosis and Management. Mayo Clin. Proc. 2019; 94 (4): 714–726. https://doi.org/10.1016/j.mayocp.2018.12.020</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Манукьян Г.B., Шерцингер А.Г., Жигалова С.Б., Семенова Т.С., Мартиросян Р.А. Первичная профилактика кровотечений из варикозно расширенных вен пищевода и желудка у больных портальной гипертензией (обзор литературы). Анналы хирургической гепатологии. 2016; 21 (2): 93–104. https://doi.org/10.16931/1995-5464.2016-2-93-104</mixed-citation><mixed-citation xml:lang="en">Manukyan G.V., Shertsinger A.G., Zhigalova S.V. et al. Primary prevention of bleeding from esophageal and gastric varices in patients with portal hypertension. Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 2016; 21 (2): 93–104. https://doi.org/10.16931/1995-5464.2016293-104 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Гарбузенко Д.В. Лечебная тактика при кровотечениях из варикозно расширенных вен желудка. Анналы хирургической гепатологии. 2007; 12 (1): 96–103.</mixed-citation><mixed-citation xml:lang="en">Garbuzenko D.V. The treatment tactics in the bleeding gastric varices. Annaly khirurgicheskoy gepatologii = Annals of HPB surgery. 2007; 12 (1): 96–103. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hapke R.Z.A., Benner K.G., Rosen H.R., Flora K.D. Prevention of first variceal hemorrhage – a survey of community practice patterns [Abstract]. Hepatology. 1997; 26 (Pt 1): A30.</mixed-citation><mixed-citation xml:lang="en">Hapke R.Z.A., Benner K.G., Rosen H.R., Flora K.D. Prevention of first variceal hemorrhage – a survey of community practice patterns [Abstract]. Hepatology. 1997; 26 (Pt 1): A30.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Maurice J.B., Brodkin E., Arnold F. et al. Validation of the Baveno VI criteria to identify low risk cirrhotic patients not requiring endoscopic surveillance for varices. J. Hepatol. 2016; 65 (5): 899–905. https://doi.org/10.1016/j.jhep.2016.06.021</mixed-citation><mixed-citation xml:lang="en">Maurice J.B., Brodkin E., Arnold F. et al. Validation of the Baveno VI criteria to identify low risk cirrhotic patients not requiring endoscopic surveillance for varices. J. Hepatol. 2016; 65 (5): 899–905. https://doi.org/10.1016/j.jhep.2016.06.021</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Sandrin L., Fourquet B., Hasquenoph J.M. et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med. Biol. 2003; 29: 1705– 1713. https://doi.org/10.1016/j.ultrasmedbio.2003.07.001</mixed-citation><mixed-citation xml:lang="en">Sandrin L., Fourquet B., Hasquenoph J.M. et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med. Biol. 2003; 29: 1705– 1713. https://doi.org/10.1016/j.ultrasmedbio.2003.07.001</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Turco L., Garcia-Tsao G. Portal Hypertension: Pathogenesis and Diagnosis. Clin. Liver Dis. 2019; 23 (4): 573– 587. https://doi.org/10.1016/j.cld.2019.07.007</mixed-citation><mixed-citation xml:lang="en">Turco L., Garcia-Tsao G. Portal Hypertension: Pathogenesis and Diagnosis. Clin. Liver Dis. 2019; 23 (4): 573– 587. https://doi.org/10.1016/j.cld.2019.07.007</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Robinson K.A., Middleton W.D., Al-Sukaiti R. et al. Doppler sonography of portal hypertension. Ultrasound Q. 2009; 25 (1): 3–13. https://doi.org/10.1097/RUQ.0b013e31819c8685</mixed-citation><mixed-citation xml:lang="en">Robinson K.A., Middleton W.D., Al-Sukaiti R. et al. Doppler sonography of portal hypertension. Ultrasound Q. 2009; 25 (1): 3–13. https://doi.org/10.1097/RUQ.0b013e31819c8685</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Гуревич А.И., Зубарева Е.А., Богуславская М.А., Титова Е.А., Вокуева Т. И., Кочетова Е. А. Методические рекомендации. Ультразвуковые методы исследования в педиатрии (методика проведения и возрастные нормы). 2020.</mixed-citation><mixed-citation xml:lang="en">Gurevich A.I., Zubareva E.A., Boguslavskaya M.A. et al. Methodological recommendations. Ultrasound research methods in pediatrics (methodology and age standards). 2020 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Boregowda U., Umapathy C., Halim N. et al. Update on the management of gastrointestinal varices. Wld J. Gastrointest. Pharmacol. Ther. 2019; 10 (1): 1–21. https://doi.org/10.4292/wjgpt.v10.i1.1</mixed-citation><mixed-citation xml:lang="en">Boregowda U., Umapathy C., Halim N. et al. Update on the management of gastrointestinal varices. Wld J. Gastrointest. Pharmacol. Ther. 2019; 10 (1): 1–21. https://doi.org/10.4292/wjgpt.v10.i1.1</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Matsuo M., Kanematsu M., Kim T. et al. Esophageal varices: diagnosis with gadolinium-enhanced MR imaging of the liver for patients with chronic liver damage. Am. J. Roentgenol. 2003; 180 (2): 461–466. https://doi.org/10.2214/ajr.180.2.1800461</mixed-citation><mixed-citation xml:lang="en">Matsuo M., Kanematsu M., Kim T. et al. Esophageal varices: diagnosis with gadolinium-enhanced MR imaging of the liver for patients with chronic liver damage. Am. J. Roentgenol. 2003; 180 (2): 461–466. https://doi.org/10.2214/ajr.180.2.1800461</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Мигунова Е.В., Хубутия М.Ш., Кудряшова Н.Е., Синякова О.Г., Бердников Г.А, Рей С.И., Новрузбеков М.С., Олисов О.Д. Возможности радионуклидной диагностики при диффузных заболеваниях печени и портальной гипертензии. Трансплантология. 2019; 11 (3): 188–200. https://doi.org/10.23873/2074-0506-2019-11-3-188-200</mixed-citation><mixed-citation xml:lang="en">Migunova E.V., Khubutiya M.S., Kudryashova N.E. et al. The potential of radionuclide diagnostic imaging in diffuse liver disease and portal hypertension. Transplantologiya. The Russian Journal of Transplantation. 2019; 11 (3): 188–200. https://doi.org/10.23873/2074-0506-2019-11-3-188-200</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Blakemore A.H., Lord J.W. The technic of using vitallium tubes in establishing portacaval shunts for portal hypertension. Ann. Surg. 1945; 122 (4): 476–489. https://doi.org/10.1097/00000658-194510000-00002</mixed-citation><mixed-citation xml:lang="en">Blakemore A.H., Lord J.W. The technic of using vitallium tubes in establishing portacaval shunts for portal hypertension. Ann. Surg. 1945; 122 (4): 476–489. https://doi.org/10.1097/00000658-194510000-00002</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Rosemurgy A.S., Serafini F.M., Zweibel B.R. et al. Transjugular intrahepatic portosystemic shunt vs. smalldiameter prosthetic H-graft portacaval shunt: extended follow-up of an expanded randomized prospective trial. J. Gastrointest. Surg. 2000; 4 (6): 589–597. https://doi.org/10.1016/s1091-255x(00)80107-9</mixed-citation><mixed-citation xml:lang="en">Rosemurgy A.S., Serafini F.M., Zweibel B.R. et al. Transjugular intrahepatic portosystemic shunt vs. smalldiameter prosthetic H-graft portacaval shunt: extended follow-up of an expanded randomized prospective trial. J. Gastrointest. Surg. 2000; 4 (6): 589–597. https://doi.org/10.1016/s1091-255x(00)80107-9</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Butler H., Alfidi R.J. Variceal bleeding and computed tomography. J. Comput. Tomogr. 1983; 7 (2): 175–178. https://doi.org/10.1016/0149-936x(83)90041-3</mixed-citation><mixed-citation xml:lang="en">Butler H., Alfidi R.J. Variceal bleeding and computed tomography. J. Comput. Tomogr. 1983; 7 (2): 175–178. https://doi.org/10.1016/0149-936x(83)90041-3</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Perri R.E., Chiorean M.V., Fidler J.L. et al. A prospective evaluation of computerized tomographic (CT) scanning as a screening modality for esophageal varices. Hepatology. 2008; 47 (5): 1587–1594. https://doi.org/10.1002/hep.22219</mixed-citation><mixed-citation xml:lang="en">Perri R.E., Chiorean M.V., Fidler J.L. et al. A prospective evaluation of computerized tomographic (CT) scanning as a screening modality for esophageal varices. Hepatology. 2008; 47 (5): 1587–1594. https://doi.org/10.1002/hep.22219</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Agarwal A., Jain M. Multidetector CT portal venography in evaluation of portosystemic collateral vessels. J. Med. Imaging Radiat. Oncol. 2008; 52 (1): 4–9. https://doi.org/10.1111/j.1440-1673.2007.01903.x</mixed-citation><mixed-citation xml:lang="en">Agarwal A., Jain M. Multidetector CT portal venography in evaluation of portosystemic collateral vessels. J. Med. Imaging Radiat. Oncol. 2008; 52 (1): 4–9. https://doi.org/10.1111/j.1440-1673.2007.01903.x</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bandali M.F., Mirakhur A., Lee E.W. et al. Portal hypertension: Imaging of portosystemic collateral pathways and associated image-guided therapy. Wld J. Gastroenterol. 2017; 23 (10): 1735–1746. https://doi.org/10.3748/wjg.v23.i10.1735</mixed-citation><mixed-citation xml:lang="en">Bandali M.F., Mirakhur A., Lee E.W. et al. Portal hypertension: Imaging of portosystemic collateral pathways and associated image-guided therapy. Wld J. Gastroenterol. 2017; 23 (10): 1735–1746. https://doi.org/10.3748/wjg.v23.i10.1735</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">El-Assaly H., Metwally L., Azzam H. et al. A comparative study of multi-detector CT portography versus endoscopy in evaluation of gastro-esophageal varices in portal hypertension patients. Egypt. J. Radiol. Nucl. Med. 2020; 51 (1): 1–10 https://doi.org/10.1186/s43055-019-0117-5</mixed-citation><mixed-citation xml:lang="en">El-Assaly H., Metwally L., Azzam H. et al. A comparative study of multi-detector CT portography versus endoscopy in evaluation of gastro-esophageal varices in portal hypertension patients. Egypt. J. Radiol. Nucl. Med. 2020; 51 (1): 1–10 https://doi.org/10.1186/s43055-019-0117-5</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Willmann J.K., Weishaupt D., Böhm T. et al. Detection of submucosal gastric fundal varices with multi-detector row CT angiography. Gut. 2003; 52 (6): 886–892. https://doi.org/10.1136/gut.52.6.886</mixed-citation><mixed-citation xml:lang="en">Willmann J.K., Weishaupt D., Böhm T. et al. Detection of submucosal gastric fundal varices with multi-detector row CT angiography. Gut. 2003; 52 (6): 886–892. https://doi.org/10.1136/gut.52.6.886</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Yudin A.L., Yumatova E.A., Yagubova K.V., Nakhaeva G.A. MSCT in Determining the Signs of Possible Bleeding from Gastric Varices. Acta Sci. Gastrointest. Disorders. 2022; 5 (11): 35–40. https://doi.org/10.31080/asgis.2022.05.0496</mixed-citation><mixed-citation xml:lang="en">Yudin A.L., Yumatova E.A., Yagubova K.V., Nakhaeva G.A. MSCT in Determining the Signs of Possible Bleeding from Gastric Varices. Acta Sci. Gastrointest. Disorders. 2022; 5 (11): 35–40. https://doi.org/10.31080/asgis.2022.05.0496</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Hirsch S., Guo J., Reiter R. et al. Towards compressionsensitive magnetic resonance elastography of the liver: sensitivity of harmonic volumetric strain to portal hypertension. J. Magn. Reson. Imaging. 2014; 39 (2): 298–306. https://doi.org/10.1002/jmri.24165</mixed-citation><mixed-citation xml:lang="en">Hirsch S., Guo J., Reiter R. et al. Towards compressionsensitive magnetic resonance elastography of the liver: sensitivity of harmonic volumetric strain to portal hypertension. J. Magn. Reson. Imaging. 2014; 39 (2): 298–306. https://doi.org/10.1002/jmri.24165</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Sandrin L., Fourquet B., Hasquenoph J.M. et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med. Biol. 2003; 29: 1705–1713. https://doi.org/10.1016/j.ultrasmedbio.2003. 07.001</mixed-citation><mixed-citation xml:lang="en">Sandrin L., Fourquet B., Hasquenoph J.M. et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med. Biol. 2003; 29: 1705–1713. https://doi.org/10.1016/j.ultrasmedbio.2003. 07.001</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Robic M.A., Procopet B., Métivier S. et al. Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease: a prospective study. J. Hepatol. 2011; 55 (5): 1017–1024. https://doi.org/10.1016/j.jhep.2011.01.051</mixed-citation><mixed-citation xml:lang="en">Robic M.A., Procopet B., Métivier S. et al. Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease: a prospective study. J. Hepatol. 2011; 55 (5): 1017–1024. https://doi.org/10.1016/j.jhep.2011.01.051</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Şirli R., Sporea I., Bota S., Raţiu I. Liver elastography for the diagnosis of portal hypertension in patients with liver cirrhosis. Med. Ultrason. 2012; 14 (3): 225–230.</mixed-citation><mixed-citation xml:lang="en">Şirli R., Sporea I., Bota S., Raţiu I. Liver elastography for the diagnosis of portal hypertension in patients with liver cirrhosis. Med. Ultrason. 2012; 14 (3): 225–230.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Castera L., Pinzani M., Bosch J. Non invasive evaluation of portal hypertension using transient elastography. J. Hepatol. 2012; 56 (3): 696–703. https://doi.org/10.1016/j.jhep.2011.07.005</mixed-citation><mixed-citation xml:lang="en">Castera L., Pinzani M., Bosch J. Non invasive evaluation of portal hypertension using transient elastography. J. Hepatol. 2012; 56 (3): 696–703. https://doi.org/10.1016/j.jhep.2011.07.005</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Gerstenmaier J.F., Gibson R.N. Ultrasound in chronic liver disease. Insights Imaging. 2014; 5 (4): 441–455. https://doi.org/10.1007/s13244-014-0336-2</mixed-citation><mixed-citation xml:lang="en">Gerstenmaier J.F., Gibson R.N. Ultrasound in chronic liver disease. Insights Imaging. 2014; 5 (4): 441–455. https://doi.org/10.1007/s13244-014-0336-2</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Han J.-Y., Cho J.H., Kwon H.J., Nam K.J. Predicting portal hypertension as assessed by acoustic radiation force impulse: correlations with the Doppler ultrasound. Br. J. Radiol. 2012; 85 (1016): 404–409. https://doi.org/10.1259/bjr/74648924</mixed-citation><mixed-citation xml:lang="en">Han J.-Y., Cho J.H., Kwon H.J., Nam K.J. Predicting portal hypertension as assessed by acoustic radiation force impulse: correlations with the Doppler ultrasound. Br. J. Radiol. 2012; 85 (1016): 404–409. https://doi.org/10.1259/bjr/74648924</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Hirsch S., Guo J., Reiter R. et al. MR elastography of the liver and the spleen using a piezoelectric driver, singleshot wave-field acquisition, and multifrequency dual parameter reconstruction. Magn. Reson. Med. 2014; 71 (1): 267–77. https://doi.org/10.1002/mrm.24674</mixed-citation><mixed-citation xml:lang="en">Hirsch S., Guo J., Reiter R. et al. MR elastography of the liver and the spleen using a piezoelectric driver, singleshot wave-field acquisition, and multifrequency dual parameter reconstruction. Magn. Reson. Med. 2014; 71 (1): 267–77. https://doi.org/10.1002/mrm.24674</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Ronot M., Lambert S., Elkrief L. et al. Assessment of portal hypertension and high-risk oesophageal varices with liver and spleen three-dimensional multifrequency MR elastography in liver cirrhosis. Eur. Radiol. 2014; 24 (6): 1394–1402. https://doi.org/10.1007/s00330-014-3124-y</mixed-citation><mixed-citation xml:lang="en">Ronot M., Lambert S., Elkrief L. et al. Assessment of portal hypertension and high-risk oesophageal varices with liver and spleen three-dimensional multifrequency MR elastography in liver cirrhosis. Eur. Radiol. 2014; 24 (6): 1394–1402. https://doi.org/10.1007/s00330-014-3124-y</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Shin S.U., Lee J.-M., Yu M.H. et al. Prediction of esophageal varices in patients with cirrhosis: usefulness of three-dimensional MR elastography with echoplanar imaging technique. Radiology. 2014; 272 (1): 143–153. https://doi.org/10.1148/radiol.14130916</mixed-citation><mixed-citation xml:lang="en">Shin S.U., Lee J.-M., Yu M.H. et al. Prediction of esophageal varices in patients with cirrhosis: usefulness of three-dimensional MR elastography with echoplanar imaging technique. Radiology. 2014; 272 (1): 143–153. https://doi.org/10.1148/radiol.14130916</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Vizzutti F., Arena U., Romanelli R.G. et al. Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis. Hepatology. 2007; 45 (5): 1290–1297. https://doi.org/10.1002/hep.21665</mixed-citation><mixed-citation xml:lang="en">Vizzutti F., Arena U., Romanelli R.G. et al. Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis. Hepatology. 2007; 45 (5): 1290–1297. https://doi.org/10.1002/hep.21665</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Stefanescu H., Radu C., Procopet B. et al. Noninvasiveménage à troisfor the prediction of high-risk varices: stepwise algorithm using lok score, liver and spleen stiffness. Liver International. 2014; 35 (2): 317–325. https://doi.org/10.1111/liv.12687</mixed-citation><mixed-citation xml:lang="en">Stefanescu H., Radu C., Procopet B. et al. Noninvasiveménage à troisfor the prediction of high-risk varices: stepwise algorithm using lok score, liver and spleen stiffness. Liver International. 2014; 35 (2): 317–325. https://doi.org/10.1111/liv.12687</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Kim J.-H., Nam S.-J. Capsule Endoscopy for Gastric Evaluation. Diagnostics. 2021; 11: 1792. https://doi.org/10.3390/diagnostics11101792</mixed-citation><mixed-citation xml:lang="en">Kim J.-H., Nam S.-J. Capsule Endoscopy for Gastric Evaluation. Diagnostics. 2021; 11: 1792. https://doi.org/10.3390/diagnostics11101792</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
