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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1232</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1290</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Плеврит и перикардит как причина атипичной боли в грудной клетке у пациентов в раннем периоде после COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Pleurisy and pericarditis as a cause of atypical chest pain in patients with in early post-COVID-19 period</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7858-7820</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сукмарова</surname><given-names>З. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukmarova</surname><given-names>Z. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сукмарова Зульфия Наилевна – кандидат медицинских наук, научный сотрудник лаборатории системной красной волчанки </p><p>115522 Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>Zulfiya N. Sukmarova – Cand. of Sci. (Med.), Researcher of Laboratory of Systemic Lupus Erythematosus</p><p>34A, Kashirskoye shosse, Moscow 115522</p></bio><email xlink:type="simple">suzulfia@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5658-9190</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрагимова</surname><given-names>Ф. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibragimova</surname><given-names>F. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ибрагимова Фируза Мирдиевна – заведующая отделением УЗИ сосудов </p><p>Москва</p></bio><bio xml:lang="en"><p>Firuza M. Ibragimova – Head of the Vascular Ultrasound Department</p><p>8А, Bol. Olenya str., Moscow 107014</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2484-5249</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларина</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Larina</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ларина Ольга Михайловна – кандидат медицинских наук, заведующая отделением лучевой диагностики </p><p>Москва</p></bio><bio xml:lang="en"><p>Olga M. Larina – Cand. of Sci. (Med.), Head of the Department of Radiation Diagnostics </p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9014-9022</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Громов Александр Игоревич – доктор медицинских наук, профессор, профессор кафедры лучевой диагностики </p><p>Москва</p><p> </p></bio><bio xml:lang="en"><p>Alexander I. Gromov – Doct. of Sci. (Med.), Professor</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1598-8360</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Насонов Евгений Львович – академик РАН, доктор медицинских наук, научный руководитель</p><p>Москва</p></bio><bio xml:lang="en"><p>Evgeny L. Nasonov – Academician of the Russian Academy of Sciences, Doct. of Sci. (Med.), scientific director</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ “НИИ ревматологии им. В.А. Насоновой”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Центральный военный клинический госпиталь им. П.В. Мандрыка МО РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Military Clinical Hospital named by P.V. Mandryk Ministry of Defense of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ “НМИЦ отоларингологии ФМБА России”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific medical research center Otolaryngology of the Federal Medical and Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО “Московский государственный медико-стоматологический университет им. А.И. Евдокимова” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>30</day><month>11</month><year>2022</year></pub-date><volume>26</volume><issue>4</issue><fpage>11</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сукмарова З.Н., Ибрагимова Ф.М., Ларина О.М., Громов А.И., Насонов Е.Л., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Сукмарова З.Н., Ибрагимова Ф.М., Ларина О.М., Громов А.И., Насонов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Sukmarova Z.N., Ibragimova F.M., Larina O.M., Gromov A.I., Nasonov E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1290">https://medvis.rdsmedia.ru/jour/article/view/1290</self-uri><abstract><p>Во время пандемии на приеме кардиолога возросло количество пациентов с неангинальной болью в грудной клетке.</p><sec><title>Цель исследования</title><p>Цель исследования: оценить встречаемость признаков плеврита и перикардита после COVID-19 у некоморбидных пациентов с атипичной болью в грудной клетке и описать их характеристики по данным эхокардиографии и магнитно-резонансной томографии.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. С февраля 2021 г. по январь 2022 г. в исследование проспективно последовательно включено 200 пациентов, амбулаторно обратившихся к кардиологу с дискомфортом в области сердца, впервые возникшим после перенесенной новой коронавирусной инфекции. Критерии включения: 18–50 лет, 5–12 нед после заражения SARS-CoV-2, неангинозный характер боли в грудной клетке. Критерии исключения: пневмония или признаки тромбоэмболии ветвей легочной артерии, коронарная болезнь сердца, застойная сердечная или почечная недостаточность, онкопатология, химиотерапия, лучевая терапия органов грудной клетки в анамнезе. Проводился опрос (да/нет) на наличие общего недомогания, ухудшения качества жизни, гипертермии, кашля. Ультразвуковое исследование перикарда и плевры на выявление выпота или поствоспалительных изменений выполнялось в соответствии с рекомендациями. При плохой ультразвуковой визуализации или отсутствии признаков поражения перикарда или плевры у пациентов с типичными симптомами проводилась магнитно-резонансная томография.</p></sec><sec><title>Результаты</title><p>Результаты. В исследование включено 82 женщины и 118 мужчин 39 (28–46) лет. С учетом клиники перикардит диагностирован у 152 (76%) пациентов, из них выпотной перикардит – у 119 (78%), миокардит – у 6 (3%) и миоперикардит – у 49 (25%) пациентов, плеврит выявлен у 22 (11%) пациентов, экссудативный плеврит – у 11 (5,5%) с преимущественным односторонним поражением прилежащей к сердцу медиастинально-диафрагмальной области. Гипертермия регистрировалась в 2,5% случаев, общее недомогание и снижение качества жизни отмечали 60 и 84% пациентов.</p></sec><sec><title>Выводы</title><p>Выводы. Воспаление серозных оболочек как причина атипичной боли в грудной клетке среди молодых некоморбидных пациентов в раннем периоде после COVID-19 выявлено у 87% пациентов. В ближайшие годы, вероятно, стоит проводить ультразвуковое исследование перикарда и плевры всем пациентам с болью в грудной клетке.</p></sec></abstract><trans-abstract xml:lang="en"><p>During the pandemic COVID-19, there has been an increase in the number of patients with non-anginal chest pain at cardiologist appointments.</p><sec><title>Objective</title><p>Objective. To assess the incidence of signs of pleurisy and pericarditis after COVID-19 in non-comorbid patients with atypical chest pain and describe their characteristics according to echocardiography and magnetic resonance imaging.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. From February 2021 to January 2022, 200 outpatients were prospectively enrolled in the study, all of them suffered from a discomfort in the heart region for the first time after SARS-CoV-2 infection. Inclusion criteria: 18–50 years old, 5–12 weeks after SARS-CoV-2 infection, non-anginal chest pain. Exclusion criteria: pneumonia or signs of pulmonary thromboembolism, coronary heart disease, congestive heart failure or kidney disease, clinical or laboratory signs of myocarditis, oncopathology, radiation or chemotherapy of the chest in past medical history. A survey was conducted (yes/no) for the presence of general malaise, quality of life deterioration, hyperthermia, cough. Ultrasound examination of the pericardium and pleura to detect effusion or postinflammatory changes was performed in accordance with the recommendations. Magnetic resonance imaging was performed if ultrasound imaging was poor or there was no evidence of pericardial or pleural involvement in patients with typical symptoms.</p></sec><sec><title>Results</title><p>Results. 82 women and 118 men were included. Median of age 39 [28–46] years old. Pericarditis was diagnosed in 152 (76%) patients, including effusive pericarditis in 119 (78%), myocarditis in 6 (3%) and myopericarditis</p><p>in 49 (25%) patients, pleurisy was detected in 22 (11%) patients, exudative pleurisy – in 11 (5.5%) patients with a predominant unilateral lesion of the mediastinal-diaphragmatic region adjacent to the heart. Hyperthermia was recorded in 2.5% of cases, general malaise – in 60% and a decrease in the quality of life – in 84%.</p></sec><sec><title>Conclusion</title><p>Conclusion. Serositis as a cause of atypical chest pain among young non-comorbid patients in early postCOVID was identified in 87% of patients. In the coming years, it is probably worthwhile to perform ultrasound of the pericardium and pleura in all patients with chest pain.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>перикардит</kwd><kwd>плеврит</kwd><kwd>серозит</kwd><kwd>эхокардиография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>pericarditis</kwd><kwd>pleurisy</kwd><kwd>serositis</kwd><kwd>echocardiography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов Е.Л. Коронавирусная болезнь 2019 (COVID-19): размышления ревматолога. Научно-практическая ревматология. 2020; 58 (2): 123–132. http://doi. org/10.14412/1995-4484-2020-123-132</mixed-citation><mixed-citation xml:lang="en">Nasonov E.L. Coronavirus disease 2019 (COVID-19): a rheumatologist’s thoughts. 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