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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1276</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1276</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГОЛОВА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEAD</subject></subj-group></article-categories><title-group><article-title>Клиническое 9-месячное наблюдение орбитального венозного варикоза с внутрипросветным тромбом с использованием лучевых методов</article-title><trans-title-group xml:lang="en"><trans-title>Clinical case of 9-month observation of orbital venous varicose with intraluminal thrombus using radiologic methods</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1827-606X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенов</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenov</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенов Станислав Евгеньевич – доктор мед. наук, ведущий научный сотрудник лаборатории лучевых методов диагностики НИИ КПССЗ</p><p>тел. +7-923-515-69-21</p><p>650002 Кемерово, Сосновый бульвар, д. 6</p></bio><bio xml:lang="en"><p>Stanislav E. Semenov – Doct. of Sci. (Med.), PhD, Leading Researcher, Laboratory of Radiolocic Methods of Diagnostics</p><p>phone: +7-923-515-69-21</p><p>6, Sosnoviy Blvd., Kemerovo 650002</p></bio><email xlink:type="simple">dr_semenov_s@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7943-9937</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малков</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Malkov</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малков Иван Николаевич – клинический ординатор НИИ КПССЗ</p><p>650002 Кемерово, Сосновый бульвар, д. 6</p></bio><bio xml:lang="en"><p>Ivan N. Malkov – Ordinator</p><p>6, Sosnoviy Blvd., Kemerovo 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0485-4586</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шатохина</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatokhina</surname><given-names>M. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шатохина Мария Геннадьевна – канд. мед. наук, ассистент кафедры лучевой диагностики и медицинской визуализации с клиникой Института медицинского образования</p><p>197341 Санкт-Петербург, ул. Аккуратова, д. 2</p></bio><bio xml:lang="en"><p>Maria G. Shatokhina – Cand. of Sci. (Med.), Assistant of the Department of Radiology and Medical Imaging with the clinic of the Institute of Medical Education</p><p>2, Akkuratova str., Saint-Petersburg 197341</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2146-2242</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаранина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Garanina</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаранина Нина Альбертовна – врач-офтальмолог</p><p>650000 Кемерово, Октябрьский пр., 22</p></bio><bio xml:lang="en"><p>Nina A. Garanina – ophthalmologist</p><p>22, Oktyabrsky ave., Kemerovo 650000</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0846-4200</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Молдавская</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moldavskaya</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Молдавская Ирина Валерьевна – канд. мед. наук, руководитель регионального сосудистого центра, заведующая отделением неврологии</p><p>650002 Кемерово, Сосновый бульвар, д. 6</p></bio><bio xml:lang="en"><p>Irina V. Moldavskaya – Cand. of Sci. (Med.), Head of the Regional Vascular Center, Head of Neurology Department</p><p>6, Sosnoviy blvd., Kemerovo 650002</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7573-0636</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коков Александр Николаевич – канд. мед. наук, заведующий лабораторией лучевых методов диагностики НИИ КПССЗ</p><p>650002 Кемерово, Сосновый бульвар, д. 6</p></bio><bio xml:lang="en"><p>Alexander N. Kokov – Cand. of Sci. (Med.), Head of Laboratory of Radiolocic Methods of Diagnostics</p><p>6, Sosnoviy Blvd., Kemerovo 650002</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ “Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний” Министерства науки и высшего образования Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ “Национальный медицинский исследовательский центр им. В.А. Алмазова” Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГАУЗ “Кузбасская областная клиническая больница им. С.В. Беляева”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuzbass Regional Clinical Hospital named after S.V. Belyaev</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ “Кузбасский клинический кардиологический диспансер им. академика Л.С. Барбараша”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuzbass Cardiology Centre named after L.S. Barbarash</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>03</day><month>11</month><year>2023</year></pub-date><volume>28</volume><issue>1</issue><fpage>35</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенов С.Е., Малков И.Н., Шатохина М.Г., Гаранина Н.А., Молдавская И.В., Коков А.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Семенов С.Е., Малков И.Н., Шатохина М.Г., Гаранина Н.А., Молдавская И.В., Коков А.Н.</copyright-holder><copyright-holder xml:lang="en">Semenov S.E., Malkov I.N., Shatokhina M.G., Garanina N.A., Moldavskaya I.V., Kokov A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1276">https://medvis.rdsmedia.ru/jour/article/view/1276</self-uri><abstract><p>Представлен редкий клинический случай тромбоза варикозно расширенной верхней глазничной вены в сочетании с унилатеральной венозной аномалией развития подкорковой области головного мозга с успешной антитромботической терапией. Варикозное расширение верхней глазничной вены встречается редко (2% от всех образований орбиты), является предрасполагающим фактором тромбоза вены.</p><sec><title>Материал и методы</title><p>Материал и методы. Пациентка 41 года с верифицированным тромбозом одностороннего орбитального венозного варикоза наблюдалась в течение 9 мес. Первично выполнены МСКТ головного мозга и МСКТ-ангиография, затем динамическое наблюдение осуществлялось выполнением МРТ головного мозга и МР-венографии, в заключение выполнено УЗИ орбиты.</p><p>Описание клинического наблюдения. Клиническая картина состояла из небольшого непульсирующего одностороннего экзофтальма, легкого птоза, периорбитального отека мягких тканей, подконъюнктивального кровоизлияния, параорбитальной гематомы, венозной дисфункции на глазном дне. При МСКТ и МСКТ-ангиографии обнаружен тромб внутри мешка орбитального венозного варикоза. Заболевание, вероятно, носило вторичный характер, учитывая, что сочеталось с венозной ангиомой подкорковой области с той же стороны. В течение 9 мес наблюдения для контроля эффективности терапии трижды выполнялась МРТ до и после контрастного усиления, которая показала постепенное уменьшение экзофтальма, размеров тромба и мешка варикоцеле, что сопровождалось постепенным улучшением клинической картины до субъективного выздоровления.</p></sec><sec><title>Заключение</title><p>Заключение. МРТ явилась столь же хорошим методом визуализации, как и МСКТ, и, на наш взгляд, более предпочтительным из-за отсутствия лучевой нагрузки и необходимости применения йодистого контрастного средства.</p></sec></abstract><trans-abstract xml:lang="en"><p>A rare clinical case of thrombosis of varicose superior ophthalmic vein in combination with a unilateral venous anomaly of the subcortical region of the brain with successful antithrombotic therapy is presented. Varicose veins of the superior ophthalmic vein are rare (2% of all orbital formations) and are a risk factor for thrombosis.</p><sec><title>Material and methods</title><p>Material and methods. A 41-year-old patient with verified thrombosis of unilateral orbital venous varicose veins was observed for 9 months. Initially, MSCT of the brain and MSCT angiography were performed, then dynamic monitoring was carried out by performing MRI of the brain and MR venography, and finally an ultrasound examination of the orbit was performed.</p><p>Description of a clinical case. The clinical presentation consisted of a slight non-pulsatile unilateral exophthalmos, mild ptosis, periorbital soft tissue edema, subconjunctival hemorrhage, paraorbital hematoma, and venous dysfunction in the fundus. MSCT and MSCT angiography revealed a thrombus inside the sac of orbital venous varicose veins. The disease was probably secondary in nature, given that it was combined with venous angioma of the subcortical region on the same side. During 9 months of observation, to monitor the effectiveness of therapy, MRI was performed three times before and after contrast enhancement, which showed a gradual decrease in exophthalmos, the size of the thrombus and the varicocele sac, which was accompanied by a gradual improvement in the clinical picture until subjective recovery.</p></sec><sec><title>Conclusion</title><p>Conclusion. MRI was as good an imaging modality as MSCT, and, in our opinion, more preferable due to the absence of radiation exposure and the need for iodine contrast agent.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>тромбоз</kwd><kwd>орбитальный венозный варикоз</kwd><kwd>венозная ангиома</kwd><kwd>МСКТ</kwd><kwd>МРТ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thrombosis</kwd><kwd>orbital venous varicose</kwd><kwd>venous angioma</kwd><kwd>MSCT</kwd><kwd>MRI</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chen L., Guo U.S., Grutman G. et al. Superior Ophthalmic Vein Thrombosis Induced by Orbital Cellulitis: An Ophthalmic Emergency. Cureus. 2021; 13 (10): e19038. http://doi.org/10.7759/cureus.19038</mixed-citation><mixed-citation xml:lang="en">Chen L., Guo U.S., Grutman G. et al. 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