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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1275</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1275</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Возможности КТ в диагностике аспергиллеза легких у пациентов с COVID-19 (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of CT in the diagnosis of pulmonary aspergillosis in patients with COVID-19 (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7427-0810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Най</surname><given-names>Мьо Тун</given-names></name><name name-style="western" xml:lang="en"><surname>Nay</surname><given-names>Myo Tun</given-names></name></name-alternatives><bio xml:lang="ru"><p>Най Мьо Тун – аспирант кафедры лучевой диагностики и терапии</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Nay Myo Tun – graduate student of radiology department</p><p>house 1, Ostrovityanova str., Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0310-0889</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юдин</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Yudin</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юдин Андрей Леонидович – доктор мед. наук, профессор, заведующий кафедрой лучевой диагностики и терапии МБФ</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Andrey L. Yudin – Doct. of Sci. (Med.), Professor, Head of radiology department</p><p>house 1, Ostrovityanova str., Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9446-2163</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абович</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Abovich</surname><given-names>Y. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абович Юлия Александровна – канд. мед. наук, доцент кафедры лучевой диагностики и терапии МБФ</p><p>117997 Москва, ул. Островитянова, д. 1</p><p>Тел.: +7-916-118-73-28</p></bio><bio xml:lang="en"><p>Yulia A. Abovich – Cand. of Sci. (Med.), associate professor of radiology department</p><p>house 1, Ostrovityanova str., Moscow 117997</p><p>Phone: +7-916-118-73-28</p></bio><email xlink:type="simple">abovich@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО “Российский национальный исследовательский медицинский университет им. Н.И. Пирогова” Минздрава России</institution><country>Мьянма</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Myanmar</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>17</day><month>07</month><year>2023</year></pub-date><volume>27</volume><issue>4</issue><fpage>10</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Най М.Т., Юдин А.Л., Абович Ю.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Най М.Т., Юдин А.Л., Абович Ю.А.</copyright-holder><copyright-holder xml:lang="en">Nay M.T., Yudin A.L., Abovich Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1275">https://medvis.rdsmedia.ru/jour/article/view/1275</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: проанализировать последние исследования в области КТ-диагностики аспергиллеза легких у пациентов c COVID-19 по данным отечественной и зарубежной литературы.</p></sec><sec><title>Результаты</title><p>Результаты. Аспергиллез легких – одно из наиболее распространенных жизнеугрожающих грибковых заболеваний, которое вызывается вдыханием спор плесени Aspergillus и поражает все отделы дыхательной системы. В последние годы отмечено резкое увеличение случаев инвазивных микотических процессов. В период пандемии COVID-19, по данным ряда авторов, частота развития аспергиллеза легких достигала 34,4%, а летальность – 74%. Всемирная организация здравоохранения призывает “свести к минимуму несоразмерное использование кортикостероидов и антибиотиков для легких случаев и случаев средней тяжести”. Она пояснила, что кортикостероиды в тяжелых случаях действительно спасают жизнь, но их массовое применение может вызывать грибковые инфекции. Данное осложнение все чаще встречается у больных после кортикостероидной и антибактериальной терапии, с иммунодефицитными состояниями, а также проходивших лечение в отделениях интенсивной терапии. Пандемия COVID-19 создала дополнительные проблемы в диагностике, лечении и профилактике грибковых осложнений. Клинические и рентгенологические признаки грибковых инфекций во многом сходны с типичными легочными проявлениями COVID-19. Проведен сравнительный анализ КТ-признаков различных форм аспергиллеза легких до и во время пандемии COVID-19 по данным литературы. Выделены основные КТ-симптомы микотического поражения легких среди пациентов, перенесших COVID-19. В настоящее время компьютерная томография имеет решающее значение, в первую очередь, для выявления и мониторинга осложнений COVID-19, включая присоединение вторичной грибковой инфекции.</p></sec><sec><title>Заключение</title><p>Заключение. Для постановки заключения о микозе в ранние сроки требуется особая настороженность и высокая квалификация врача-рентгенолога, что, в свою очередь, будет способствовать своевременному назначению противогрибковой терапии, позволяющей снизить заболеваемость и смертность.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: to analyze the latest research in the field of CT diagnostics of pulmonary aspergillosis in patients with COVID-19 according to domestic and foreign literature.</p></sec><sec><title>Results</title><p>Results. Pulmonary aspergillosis is one of the most common life-threatening fungal diseases that is caused by inhalation of Aspergillus mold spores and affects all parts of the respiratory system. In recent years, there has been a sharp increase in cases of invasive mycotic processes. During the COVID-19 pandemic, according to a number of authors, the incidence of pulmonary aspergillosis reached 34.4%, and the mortality rate was 74%. The World Health Organization calls for “minimizing the disproportionate use of corticosteroids and antibiotics for mild and moderate cases”. She explained that corticosteroids in severe cases do save lives, but their massive use can cause fungal infections. This complication is increasingly common in patients after corticosteroid and antibiotic therapy, with immunodeficiency states, as well as those treated in intensive care units. The COVID-19 pandemic has created additional challenges in the diagnosis, treatment and prevention of fungal complications. The clinical and radiographic features of fungal infections are largely similar to typical pulmonary manifestations of COVID-19. A comparative analysis of CT signs of various forms of pulmonary aspergillosis before and during the COVID-19 pandemic was carried out according to the literature. The main CT symptoms of mycotic lung lesions among patients who have undergone COVID-19 have been identified. Currently, computed tomography is crucial, first of all, to detect and monitor complications of COVID-19, including the addition of a secondary fungal infection.</p></sec><sec><title>Conclusion</title><p>Conclusion. To make a conclusion about mycosis in the early stages, special vigilance and high qualification of the radiologist are required, which in turn will contribute to the timely appointment of antifungal therapy, which will reduce morbidity and mortality.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>аспергиллез легких</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd><kwd>КТ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary aspergillosis</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd><kwd>CT</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Harapan H., Itoh N., Yufika A. et al. Coronavirus disease 2019 (COVID-19): A literature review. J. Infect. 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