<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1228</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1228</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЕРДЦЕ И СОСУДЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEART AND VESSELS</subject></subj-group></article-categories><title-group><article-title>Особенности эластических свойств дилатированной и аневризматически расширенной грудной аорты по данным ЭКГ-синхронизированной КТ-ангиографии</article-title><trans-title-group xml:lang="en"><trans-title>Elastic properties of aorta with respect to its dilatation vs aneurysm according to ECG-synchronized CT-angiography</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2799-3260</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сазонова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sazonova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сазонова Светлана Ивановна – доктор мед. наук, ведущий научный сотрудник отдела лучевой диагностики,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Svetlana I. Sazonova – Doct. of Sci. (Med.), leading researcher, radiology department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">sazonova_si@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5564-3802</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саушкин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Saushkin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саушкин Виктор Вячеславович – канд. мед. наук, старший научный сотрудник отдела лучевой диагностики,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Viktor V. Saushkin – Cand. of Sci. (Med.), senior researcher, radiology department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">saushkin.vv@outlook.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2201-350X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панфилов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Panfilov</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панфилов Дмитрий Сергеевич – доктор мед. наук, старший научный сотрудник отделения сердечно-сосудистой хирургии,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Dmitry S. Panfilov – Doct. of Sci. (Med.), senior researcher, Cardiovascular Surgery Department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">pand2006@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0193-9453</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Варламова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Varlamova</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Варламова Юлия Вячеславовна – канд. мед. наук, врач-радиолог отдела лучевой диагностики,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Yuliya V. Varlamova – Cand. of Sci. (Med.), Radiologist, radiology department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">jul13@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9887-8214</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шипулин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shipulin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шипулин Владимир Владимирович – канд. мед. наук, младший научный сотрудник отдела лучевой диагностики,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Vladimir V. Shipulin – Cand. of Sci. (Med.), junior researcher, radiology department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">shipartphoto@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7896-4446</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Базарбекова</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazarbekova</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Базарбекова Ботажан Аскарбековна – аспирант отделения сердечно-сосудистой хирургии,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Botazhan A. Bazarbekova – graduate student, Cardiovascular Surgery Department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">botazhan.bazarbekova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1513-8614</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Завадовский</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zavadovsky</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Завадовский Константин Валерьевич – доктор мед. наук, руководитель отдела лучевой диагностики,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Konstantin V. Zavadovsky – Doct. of Sci. (Med.), Head of the radiology department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">konstz@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0217-7737</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>Б. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>B. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлов Борис Николаевич – доктор мед. наук, заведующий отделением сердечно-сосудистой хирургии,</p><p>634012 Томск, ул. Киевская, 111A</p></bio><bio xml:lang="en"><p>Boris N. Kozlov – Doct. of Sci. (Med.), senior researcher, Cardiovascular Surgery Department,</p><p>111A, Kievskaya str., Tomsk 634012</p></bio><email xlink:type="simple">bnkozlov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ кардиологии Томского Национального исследовательского медицинского центра РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Cardiology research Institute, Tomsk National medical research Center of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>13</day><month>06</month><year>2023</year></pub-date><volume>27</volume><issue>3</issue><fpage>53</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сазонова С.И., Саушкин В.В., Панфилов Д.С., Варламова Ю.В., Шипулин В.В., Базарбекова Б.А., Завадовский К.В., Козлов Б.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сазонова С.И., Саушкин В.В., Панфилов Д.С., Варламова Ю.В., Шипулин В.В., Базарбекова Б.А., Завадовский К.В., Козлов Б.Н.</copyright-holder><copyright-holder xml:lang="en">Sazonova S.I., Saushkin V.V., Panfilov D.S., Varlamova Y.V., Shipulin V.V., Bazarbekova B.A., Zavadovsky K.V., Kozlov B.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/1228">https://medvis.rdsmedia.ru/jour/article/view/1228</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: сопоставить показатели эластичности грудной аорты, определенные по данным ЭКГ-синхронизированной КТ-ангиографии, у пациентов с аневризмой и дилатацией восходящего отдела.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование было включено 20 пациентов c дилатацией восходящей аорты (40 мм ≤ максимальный диаметр аорты (Dmax) &lt; 50 мм) (подгруппа 1а), 30 больных с несиндромными аневризмами восходящей аорты (n = 30, Dmax ≥ 50 мм) (подгруппа 1б), а также 19 больных с нормальными размерами сосуда (Dmax &lt; 40 мм) в качестве контроля (группа 2). Всем пациентам была выполнена мультиспиральная компьютерно-томографическая ангиография аорты в ЭКГ-синхронизированном режиме (ЭКГсинхр.-КТ). На различных уровнях грудной аорты измеряли максимальный систолический и диастолический диаметр сосуда (Dmax) с последующим расчетом разницы между ними и индексов циркулярной деформации (CS), комплаенса, жесткости (Stiff), растяжимости стенки (для всех уровней), продольной деформации (LS).</p></sec><sec><title>Результаты</title><p>Результаты. По результатам анализа была выявлена умеренная отрицательная корреляционная взаимосвязь между возрастом пациентов и CS на всех уровнях грудной аорты (rmax = –0,33, rmin = –0,41). Подгруппы 1а и 1б по всем показателям значимо не различались. От группы контроля подгруппа 1а отличалась (p &lt; 0,05) по Stiff на уровне фиброзного кольца (ФК) аортального клапана (0,07 [–0,14; 0,15] vs –0,04 [–0,1; 0,06]), а также CS на уровне ФК и синусов Вальсальвы (СВ) (0,49 [–2,94; 3,36] vs –1,18 [–4,51; 3,87]), а подгруппа 1б – по CS на уровне СВ (3,73 [0,24; 6,56] vs 0,13 [–1,42; 3,04]) и проксималного отдела нисходящей аорты (дистальнее устья левой подключичной артерии) (5,48 [1,27; 8,40] vs 1,97 [–0,32; 6,08]), также по LS (5,96 [–8,98; 9,25] vs –2,58 [–7,75; 1,89]) на уровне дуги аорты.</p></sec><sec><title>Заключение</title><p>Заключение. По данным ЭКГсинхр. КТ-ангиографии показатели эластичности грудной аорты у пациентов с аневризмой и дилатацией восходящего отдела не различаются. По сравнению с группой контроля у больных с аневризмой восходящего отдела аорты отмечается увеличение пульсовой деформации в недилатированной зоне (дуге аорты).</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to compare the indicators of elasticity of the thoracic aorta, determined by ECG-Gated-CT angiography, in patients with ascending aortic aneurysm and dilatation.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 20 patients with dilatation of the ascending aorta (40 mm ≤ maximum aortic diameter (Dmax) &lt; 50 mm) (group 1a), 30 patients with non-syndromic aneurysms of the ascending aorta (n = 30, Dmax ≥ 50 mm) (group 1b), as well as 19 patients with normal aortic sizes (Dmax &lt; 40 mm) as controls (group 2). All patients underwent multispiral computed tomography angiography of the aorta in ECG-Gated mode (ECG-Gated -CT). Maximum systolic and diastolic aortic diameters (Dmax) were measured at different levels of the thoracic aorta, followed by calculation of the difference between them and calculation of the circular deformation (CS), compliance, stiffness (Stiff), wall distensibility, longitudinal deformation (LS).</p></sec><sec><title>Results</title><p>Results. Moderate negative correlation between the age of the patients and CS at all levels of the thoracic aorta (rmaximum = –0.33, rminimum = –0.41) was revealed. Groups 1a and 1b did not differ significantly in all parameters. Group 1a differed from the control group (p &lt; 0.05) in Stiff at the level of the aortic annulus (AA) (0.07 [–0.14; 0.15] vs –0.04 [–0.1; 0.06]), as well as CS at the level of AA and sinuses of Valsalva (SV ) (0.49 [–2.94; 3.36] vs –1.18 [–4.51; 3.87]), and group 1b – in CS at the level of SV (3.73 [0.24; 6.56] vs 0.13 [–1.42; 3.04]) and proximal part of the descending aorta (distal to the left subclavian artery) (5.48 [1.27; 8.40] vs 1.97 [–0.32; 6.08]), also in LS (5.96 [–8.98; 9.25] vs –2.58 [–7.75; 1.89]) at the level of the aortic arch.</p></sec><sec><title>Conclusion</title><p>Conclusion. According to ECG-Gated-CT angiography, the indicators of elasticity of the thoracic aorta in patients with ascending aortic aneurysm and dilatation did not differ. Compared with the control group, patients with aneurysm of the ascending aorta showed an increased pulse deformity of the non-dilated aortic arch.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>грудная аорта</kwd><kwd>аневризма</kwd><kwd>ЭКГ-синхронизированная КТ-ангиография</kwd><kwd>эластичность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thoracic aorta</kwd><kwd>aneurysm</kwd><kwd>ECG-Gated CT angiography</kwd><kwd>elasticity</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при поддержке гранта Российского научного фонда, № 21-15-00160, https://rscf.ru/project/21-15-00160/</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Isselbacher E.M. Thoracic and abdominal aortic aneurysms. Circulation. 2005; 111: 816–828. http://doi.org/10.1161/01.CIR.0000154569.08857.7A</mixed-citation><mixed-citation xml:lang="en">Isselbacher E.M. Thoracic and abdominal aortic aneurysms. Circulation. 2005; 111: 816–828. http://doi.org/10.1161/01.CIR.0000154569.08857.7A</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Davis F.M., Luo Y., Avril S. et al. Local mechanical properties of human ascending thoracic aneurysms. J. Mech. Behav. Biomed. Mater. 2016; 61: 235–249. http://doi.org/10.1016/j.jmbbm.2016.03.025</mixed-citation><mixed-citation xml:lang="en">Davis F.M., Luo Y., Avril S. et al. Local mechanical properties of human ascending thoracic aneurysms. J. Mech. Behav. Biomed. Mater. 2016; 61: 235–249. http://doi.org/10.1016/j.jmbbm.2016.03.025</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Emerel L., Thunes J., Kickliter T. et al. Predissection-derived geometric and distensibility indices reveal increased peak longitudinal stress and stiffness in patients sustaining acute type A aortic dissection: Implications for predicting dissection. J. Thorac. Cardiovasc. Surg. 2019; 158 (2): 355–363. http://doi.org/10.1016/j.jtcvs.2018.10.116</mixed-citation><mixed-citation xml:lang="en">Emerel L., Thunes J., Kickliter T. et al. Predissection-derived geometric and distensibility indices reveal increased peak longitudinal stress and stiffness in patients sustaining acute type A aortic dissection: Implications for predicting dissection. J. Thorac. Cardiovasc. Surg. 2019; 158 (2): 355–363. http://doi.org/10.1016/j.jtcvs.2018.10.116</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Isselbacher E.M., Cardenas C.L.L., Lindsay M.E. Hereditary influence in thoracic aortic aneurysm and dissection. Circulation. 2016; 133 (24): 2516–2528. http://doi.org/10.1161/CIRCULATIONAHA.116.009762</mixed-citation><mixed-citation xml:lang="en">Isselbacher E.M., Cardenas C.L.L., Lindsay M.E. Hereditary influence in thoracic aortic aneurysm and dissection. Circulation. 2016; 133 (24): 2516–2528. http://doi.org/10.1161/CIRCULATIONAHA.116.009762</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ilyushenkova J.N., Panfilov D.S., Saushkin V.V., Sonduev E.L., Kozlov B.N., Sazonova S.I. Scintigraphic imaging of inflammation in the aortic wall using 99m Tc-pyrophosphate. Sovremennye tehnologii v medicine = Modern Technologies in Medicine. 2021; 13 (6): 65–71. https://doi.org/10.17691/stm2021.13.6.07 (In Russian)</mixed-citation><mixed-citation xml:lang="en">Ilyushenkova J.N., Panfilov D.S., Saushkin V.V., Sonduev E.L., Kozlov B.N., Sazonova S.I. Scintigraphic imaging of inflammation in the aortic wall using 99m Tc-pyrophosphate. Sovremennye tehnologii v medicine = Modern Technologies in Medicine. 2021; 13 (6): 65–71. https://doi.org/10.17691/stm2021.13.6.07 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hiratzka L.F., Bakris G.L., Beckman J.A. et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation. 2014; 35 (41): 2873–2926. http://doi.org/10.1161/CIR.0b013e3181d4739e</mixed-citation><mixed-citation xml:lang="en">Hiratzka L.F., Bakris G.L., Beckman J.A. et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation. 2014; 35 (41): 2873–2926. http://doi.org/10.1161/CIR.0b013e3181d4739e</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Abugov S.A., Averina T.B., Akchurin R.S., Alekyan B.G., Arakelyan V.S., Vachev A.N., Gordeev M.L. et al. Clinical guidelines. guidelines for the diagnosis and treatment of aortic diseases (2017). The Russian Journal of Cardiology &amp; Cardiovascular Surgery. 2018: 11 (1): 7–67. (In Russian)</mixed-citation><mixed-citation xml:lang="en">Abugov S.A., Averina T.B., Akchurin R.S., Alekyan B.G., Arakelyan V.S., Vachev A.N., Gordeev M.L. et al. Clinical guidelines. guidelines for the diagnosis and treatment of aortic diseases (2017). The Russian Journal of Cardiology &amp; Cardiovascular Surgery. 2018: 11 (1): 7–67. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Adriaans B.P., Wildberger J.E., Westenberg J.J.M. et al. Predictive imaging for thoracic aortic dissection and rupture: moving beyond diameters. Eur. Radiol. 2019; 29 (12): 6396–6404. http://doi.org/10.1007/s00330-019-06320-7</mixed-citation><mixed-citation xml:lang="en">Adriaans B.P., Wildberger J.E., Westenberg J.J.M. et al. Predictive imaging for thoracic aortic dissection and rupture: moving beyond diameters. Eur. Radiol. 2019; 29 (12): 6396–6404. http://doi.org/10.1007/s00330-019-06320-7</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Koechlin L., Macius E., Kaufmann J. et al. Aortic root and ascending aorta dimensions in acute aortic dissection. Perfusion. 2020; 35 (2): 131–137. http://doi.org/10.1177/0267659119858848</mixed-citation><mixed-citation xml:lang="en">Koechlin L., Macius E., Kaufmann J. et al. Aortic root and ascending aorta dimensions in acute aortic dissection. Perfusion. 2020; 35 (2): 131–137. http://doi.org/10.1177/0267659119858848</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Iddawela S., Ravendren A., Harky A. Bio-chemomechanics of the thoracic aorta. Vasc. Biol. 2021; 12; 3 (1): 25–33. http://doi.org/10.1530/VB-20-0015. eCollection 2021.</mixed-citation><mixed-citation xml:lang="en">Iddawela S., Ravendren A., Harky A. Bio-chemomechanics of the thoracic aorta. Vasc. Biol. 2021; 12; 3 (1): 25–33. http://doi.org/10.1530/VB-20-0015. eCollection 2021.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Pasta S., Agnese V., Giuseppe M.D. et al. In Vivo Strain Analysis of Dilated Ascending Thoracic Aorta by ECG-Gated CT Angiographic Imaging. Ann. Biomed. Eng. 2017; 45 (12): 2911–2920. http://doi.org/10.1007/s10439-017-1915-4</mixed-citation><mixed-citation xml:lang="en">Pasta S., Agnese V., Giuseppe M.D. et al. In Vivo Strain Analysis of Dilated Ascending Thoracic Aorta by ECG-Gated CT Angiographic Imaging. Ann. Biomed. Eng. 2017; 45 (12): 2911–2920. http://doi.org/10.1007/s10439-017-1915-4</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Skripnik A.Yu., Fokin V.A., Mironchuk R.R., Uspenskiy V.E., Irtyuga O.B., Kushnareva E.A., Rud S.D., Lepekhina A.S., Moiseeva O.M., Trufanov G.E. Assessment of the elastic properties of the ascending aorta using electro cardiographic synchronized computed tomography angiography with advanced data processing. Russian Journal of Cardiology. 2019; 12: 48–54. https://doi.org/10.15829/1560-4071-2019-12-48-54 (In Russian)</mixed-citation><mixed-citation xml:lang="en">Skripnik A.Yu., Fokin V.A., Mironchuk R.R., Uspenskiy V.E., Irtyuga O.B., Kushnareva E.A., Rud S.D., Lepekhina A.S., Moiseeva O.M., Trufanov G.E. Assessment of the elastic properties of the ascending aorta using electro cardiographic synchronized computed tomography angiography with advanced data processing. Russian Journal of Cardiology. 2019; 12: 48–54. https://doi.org/10.15829/1560-4071-2019-12-48-54 (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Morrison T.M., Choi G., Zarins C.K., Taylor C.A. Circumferential and longitudinal cyclic strain of the human thoracic aorta: Age-related changes. J. Vasc. Surg. 2009; 49 (4): 1029–1036. http://doi.org/10.1016/j.jvs.2008.11.056</mixed-citation><mixed-citation xml:lang="en">Morrison T.M., Choi G., Zarins C.K., Taylor C.A. Circumferential and longitudinal cyclic strain of the human thoracic aorta: Age-related changes. J. Vasc. Surg. 2009; 49 (4): 1029–1036. http://doi.org/10.1016/j.jvs.2008.11.056</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Vatner S.F., Zhang J, Vyzas C. et al. Vascular Stiffness in Aging and Disease. Front. Physiol. 2021; 12: 762437. http://doi.org/10.3389/fphys.2021.762437</mixed-citation><mixed-citation xml:lang="en">Vatner S.F., Zhang J, Vyzas C. et al. Vascular Stiffness in Aging and Disease. Front. Physiol. 2021; 12: 762437. http://doi.org/10.3389/fphys.2021.762437</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zubair M.M., de Beaufort H.W.L., Belvroy V.M. et al. Impact of Cardiac Cycle on Thoracic Aortic Geometry – Morphometric Analysis of Ecg Gated Computed Tomography. Ann. Vasc. Surg. 2020; 65: 174–182. http://doi.org/10.1016/j.avsg.2019.10.072</mixed-citation><mixed-citation xml:lang="en">Zubair M.M., de Beaufort H.W.L., Belvroy V.M. et al. Impact of Cardiac Cycle on Thoracic Aortic Geometry – Morphometric Analysis of Ecg Gated Computed Tomography. Ann. Vasc. Surg. 2020; 65: 174–182. http://doi.org/10.1016/j.avsg.2019.10.072</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">de Beaufort H.W., Nauta F.J., Conti M. et al. Extensibility and Distensibility of the Thoracic Aorta in Patients with Aneurysm. Eur. J. Vasc. Endovasc. Surg. 2017; 53 (2): 199–205. http://doi.org/10.1016/j.ejvs.2016.11.018</mixed-citation><mixed-citation xml:lang="en">de Beaufort H.W., Nauta F.J., Conti M. et al. Extensibility and Distensibility of the Thoracic Aorta in Patients with Aneurysm. Eur. J. Vasc. Endovasc. Surg. 2017; 53 (2): 199–205. http://doi.org/10.1016/j.ejvs.2016.11.018</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Mitéran J., Bouchot O., Cochet A., Lalande A. Automatic determination of aortic compliance based on MRI and adapted curvilinear detector. Biomed. Signal Process Control. 2018; 40: 295–311. http://doi.org/10.1016/j.bspc.2017.09.002</mixed-citation><mixed-citation xml:lang="en">Mitéran J., Bouchot O., Cochet A., Lalande A. Automatic determination of aortic compliance based on MRI and adapted curvilinear detector. Biomed. Signal Process Control. 2018; 40: 295–311. http://doi.org/10.1016/j.bspc.2017.09.002</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
