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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvis-12</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОСТИ И СУСТАВЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BONES AND JOINTS</subject></subj-group></article-categories><title-group><article-title>Изменение площади поперечного сечения срединного нерва на различных стадиях синдрома запястного канала</article-title><trans-title-group xml:lang="en"><trans-title>Cross Sectional Area Change Of The Median Nerve at Different Stages of Carpal Tunnel Syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малецкий</surname><given-names>Эдуард Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Maletskiy</surname><given-names>Eduard Yuryevich</given-names></name></name-alternatives><email xlink:type="simple">edikm@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александров</surname><given-names>Николай Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Alexandrov</surname><given-names>Nikolay Yuryevich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ицкович</surname><given-names>Ирина Эммануиловна</given-names></name><name name-style="western" xml:lang="en"><surname>Itskovich</surname><given-names>Irina Emmanuilovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобзин</surname><given-names>Сергей Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Lobzin</surname><given-names>Sergey Vladimirovich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вильяр</surname><given-names>Флорес Флор</given-names></name><name name-style="western" xml:lang="en"><surname>Villar</surname><given-names>Flores Flor</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-West State Medical University named I.I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2014</year></pub-date><volume>0</volume><issue>1</issue><fpage>102</fpage><lpage>109</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малецкий Э.Ю., Александров Н.Ю., Ицкович И.Э., Лобзин С.В., Вильяр Ф.Ф., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Малецкий Э.Ю., Александров Н.Ю., Ицкович И.Э., Лобзин С.В., Вильяр Ф.Ф.</copyright-holder><copyright-holder xml:lang="en">Maletskiy E.Y., Alexandrov N.Y., Itskovich I.E., Lobzin S.V., Villar F.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.rdsmedia.ru/jour/article/view/12">https://medvis.rdsmedia.ru/jour/article/view/12</self-uri><abstract><p>Цель: оценить изменение площади поперечного сечения (ППС) срединного нерва на разных стадиях синдрома запястного канала (СЗК). Материал и методы. В исследование вошло 62 пациента, которых разделили на 2 группы. В основной группе исследовали 85 срединных нервов у 48 (77%) человек (преобладали женщины - 36 (75%)) в возрасте от 21 года до 86 лет (средний возраст 56,7 ± 3,99 года) с клинической картиной СЗК. В качестве контроля исследовали 23 срединных нерва у 14 (23%) здоровых пациентов (преобладали женщины - 10 (71%)) в возрасте от 21 года до 53 лет (средний возраст 35,07 ± 6,22 года). Степень поражения нерва определяли с помощью электрофизиологического исследования (Nicolet Viking Select). По показателям невральной проводимости выделили различные стадии повреждения срединного нерва: легкая - 17 (20%), средняя - 44 (52%), выраженная - 20 (24%), резко выраженная - 4 (5%). У обследуемых контрольной группы (n = 23) показатели проводимости были нормальными. ППС измеряли с помощью УЗИ (GE Logiq 9) на предплечье (S1), перед входом в запястный канал (S2), в канале запястья (S3), на выходе из запястного канала (S4). Площадь сечения ветвей срединного нерва измеряли на ладони (S5). Результаты. На всех стадиях невропатии установлена высокая прямая корреляционная зависимость между степенью нарушения проведения и ППС нерва, наиболее сильно выраженная в сегментах S2 и S4 (r +0,69, +0,58; р &lt; 0,05). На стадиях с сохраненной сенсорной проводимостью (легкая и средняя степени) и у здоровых пациентов выявлена очень высокая обратная корреляционная зависимость между ППС и скоростью сенсорного проведения в соответствующем сегменте нерва (r = -0,79; р &lt; 0,05). Выводы. На всех стадиях СЗК увеличение ППС хорошо соотносится со степенью поражения нерва, определяемой электрофизиологическими методами. На стадиях с сохраненной сенсорной проводимостью и у здоровых пациентов увеличение ППС сопровождается снижением скорости сенсорного проведения в сегменте нерва.</p></abstract><trans-abstract xml:lang="en"><p>Objectives. Assessment of changes of cross-sectional area (CSA) on different segments of median nerve at different stages of carpal tunnel syndrome (CTS). Methods and materials. The study included 62 patients divided into two groups. In the basic group examined 48 (77%) patients (dominated by women - 36 (75%)), aged 21-86 years (mean age - 56,7 ± 3,99) with clinical picture of CTS and 85 median nerves were studied. 14 (23%) healthy individuals (dominated by women - 10 (71%)), aged 21-53 years (mean - 35,07 ± 6,22) with 23 median nerves studied served as a control. The degree of neuropathy was established by electrophysiological study (Nicolet Viking Select). According to nerve conduction data the different degree of median nerve injury were established: mild -17 (20%), moderate - 44 (52%), severe - 20 (24%), extreme - 4 (5%). CSA was measured by ultrasonography (10-14 MHz linear-array probe, GE Logiq 9) on antebrachi-um (S1), before the nerve entrance to carpal tunnel (S2), on the level of carpal tunnel (S3) just distal to carpal tunnel (S4), cumulative area of distal median nerve branches (S5). Results. We have found the best correlation between severity of neuropathy and CSA, measured at S2 and S4 on all stages of neuropathy (r +0,69, +0,58; р &lt; 0,05). At stages mild to moderate (with preserved sensory conduction) negative correlation between CSA and sensory nerve conduction velocity on the wrist (r = -0,79; р &lt; 0,05) was found. Conclusion. Increase in CSA of median nerve well correlates with the degree of nerve injury at all stages of CTS. CSA measured at S2 and S4 seems to have better correlation with severity of median nerve neuropathy in CTS in compare with CSA measured on other segments. In patients with preserved sensory conduction increase in CSA accompanied by a decrease in conduction velocity in a segment of the nerve.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>невропатия</kwd><kwd>синдром запястного (карпального) канала</kwd><kwd>УЗИ периферических нервов</kwd><kwd>площадь поперечного сечения нерва</kwd><kwd>электронейромиография</kwd><kwd>скорость проведения по нерву</kwd><kwd>neuropathy</kwd><kwd>carpal tunnel syndrome</kwd><kwd>high resolution sonography of peripheral nerves</kwd><kwd>nerve cross-sectional area</kwd><kwd>nerve conduction study</kwd><kwd>nerve conduction velocity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Atroshi I., Gummesson C., Johnsson R. et al. Prevalence of carpal tunnel syndrome in a general population. 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